Rho家族GTP酶2抗体

英文名称    RND2/Rho7    

中文名称    Rho家族GTP酶2抗体    

别    名    ARHN; Rho 7; Rho family GTPase 2; Rho N; Rho related GTP-binding protein RhoN; Rho-related GTP-binding protein Rho7; Rho-related GTP-binding protein RhoN; Rho7; RhoN; Rnd 2; Rnd2; RND2_HUMAN.    

Rho家族GTP酶2抗体        

说 明 书    0.2ml      

研究领域    神经生物学  信号转导  G蛋白偶联受体  G蛋白信号      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    25kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RND2 (1-80aa)    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

Rho家族GTP酶2抗体 产品介绍    background:
The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A and Ral B, exhibit approximately 50% amino acid homology to Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7 and 8) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy-terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.

Function:
May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily.

Subunit:
Interacts with the Rho-GAP domain of RACGAP1. Interacts with UBXD5. 

Subcellular Location:
Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Lipid-anchor; Cytoplasmic side (Potential). Note=Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome.

Tissue Specificity:
Highly expressed in testis.

Similarity:
Belongs to the small GTPase superfamily. Rho family.

Database links:
UniProtKB/Swiss-Prot: P52198.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

Rho家族GTP酶2抗体 

hz-0951P LH(Luteinizing Hormone)  促黄体生成素抗原

hz-0952P LH(Luteinizing Hormone)  人促黄体生成素(多肽)

hz-0984P LH/CG Receptor(Luteinizing Hormone/Choriogonadotropin Receptor)  人促黄体生成素受体抗原

hz-1054P L-HDC (L-Histidine decarboxylase)  L-组氨酸脱羧酶抗原

hz-1058P LIF peptide  白血病抑制因子抗原

hz-1458P LIFR/CD118 peptide  白血病抑制因子受体抗原

hz-1177P Lingo-1  Nogo受体作用蛋白抗原

hz-2035P LIS1(Lissencephaly-1 protein)  无脑回的致病基因LIS1抗原

hz-0824P LFABP/FABP-1(Liver Fatty acid binding protein)  肝脏型脂肪酸结合蛋白抗原

hz-0897P LFABP/FABP-2(Liver Fatty acid binding protein)  肝脏型脂肪酸结合蛋白抗原

hz-0821P LN (laminin)  层粘连蛋白(多肽抗原)

hz-1526P Laminin Beta1 peptide  层粘连蛋白β1抗原

hz-1839P lamin A  核纤层蛋白A抗原

hz-2044P LOX-1/OLR1  凝集素样氧化型低密度脂蛋白受体

hz-0976P LPLUNC1  人鼻咽癌癌基因多肽抗原

hz-1311P LYVE-1(lymphalic vessel endotheilial hyaluronan receptor 1)  淋巴管内皮透明质酸受体抗原

hz-0439P ACE( ACE, testis-specific isoform precursor)  血管紧张素转换酶(抗原)

hz-2217P Integrin alpha E2 peptide  整合素alpha E2抗原

hz-1014P Mac-1 (Mac-1/CR3/CD11b+CD18)  巨噬细胞表面分子抗原

hz-0924P Mafa(avian)(V-maf musculoaponeurotic fibrosarcoma oncogene homolog A)  v-maf 肌腱膜纤维肉瘤癌基因同源物A抗原

hz-0817P MAGE-1  黑色素瘤相关

hz-1041P MAPKK1 (MAP kinase kinase 1)  丝裂原活化蛋白激酶激酶1抗原

hz-1425P ASK1/MAPKKK5  细胞凋亡信号调节激酶1/丝裂原活化蛋白激酶激酶激酶5抗原

hz-0792P Maspin (mammary serine protease inhibitor)  抑癌基因抗原

hz-0531P Matriptase  蛋白裂解酶（一种新的癌基因）抗原

hz-0808P HCMV UL49(Human Cytomegalovirus UL49 Gene)  人巨细胞病毒UL49抗原

hz-1419P MC-1R (melanocortin-1-receptor)  黑皮质素-1受体抗原

hz-1352P Mcl-1(myeloid cell leukhzia 1) peptide  髓样细胞白血病-1抗原

hz-1043P MDM2 (urine double minute 2)  双微体2癌基因抗原

hz-1468P MDR1(multidrug resistance 1)  多药耐药蛋白抗原

hz-1400P MEF2(myocyte enhancer-binding factor 2)  肌细胞增强因子2抗原

hz-0557P Mfn1 (Mitofusin1)  线粒体融合蛋白1

hz-1328P MT(metallothionein)  金属硫蛋白抗原