RNA聚合酶III抗体

英文名称    RNA polymerase III    

中文名称    RNA聚合酶III抗体    

别    名    B related factor 1; B-related factor 1; BRF; BRF-1; brf1; brfu; General transcription factor IIIB, 90kD subunit; GTF3B; hBRF; hTFIIIB90; RNA polymerase III; subunit 2; TAF3B2; TAF3C; TATA box-binding protein-associated factor; TF3B_HUMAN; TFIIIB90; Transcription factor IIIB 90 kDa subunit; Transcription initiation factor IIIB.    

RNA聚合酶III抗体       

说 明 书    0.2ml      

研究领域    细胞生物  染色质和核信号  信号转导  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    74kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from Human BRF1/RNA polymerase III    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

RNA聚合酶III抗体  产品介绍    background:
responsible for the synthesis of a different class of RNA. RNA polymerase I (Pol I) transcribes the rRNA (ribosomal RNA) genes for the precursor of the 28S, 18S, and 5.8S molecules of the ribosome. RNA polymerase II transcribes protein-encoding genes into mRNA (messenger RNA) and snRNA (small nuclear RNA) genes into snRNAs that influence the processing of other classes of RNA. RNA polymerase III (Pol III) transcribes the 5S rRNA genes and all of the tRNA (transfer RNA) genes. Each class of RNA polymerase is assembled from 9 to 15 different polypeptides. The RPB6 and RPB8 subunits are shared by all 3 RNA polymerases.

Function:
General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the TFIIB family.
Contains 1 TFIIB-type zinc finger.

Gene ID:
2972

Database links:

Entrez Gene: 2972 Human

Entrez Gene: 299347 Rat

Omim: 604902 Human

SwissProt: Q92994 Human

Unigene: 424484 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

RNA聚合酶III抗体  

hz-0362P Protein A  蛋白A

hz-0883P GST-Tag protein  重组谷胱甘肽-转移酶

hzsl-hz8280 Cholesterol  胆固醇

hz-0104P Beta-Amyloid(1-16)  β淀粉样肽1-16（多肽蛋白）

hz-0871P Beta-Amyloid (31-35)  β淀粉样肽31-35（多肽蛋白）

hz-0105P Beta-Amyloid(1-28)  β淀粉样肽1-28（多肽蛋白）

hz-0106P Beta-Amyloid(1-40)  β淀粉样肽（1-40）（多肽蛋白）

Y-0113 A Beta1-40 (mutation type, MT) peptide  突变型β淀粉样肽1-40

Y-0114 A Beta1-40 (H-3-me6;H-3-me13;H-3-me14; Beta-Amyloid 1-40)  β淀粉样肽1-40（结构改造）

Y-0120 A Beta29-40( Beta-Amyloid 29-40)  β淀粉样肽29-40(野生型)

Y-0121 A Beta29-42( Beta-Amyloid 29-42)  β淀粉样肽29-42(野生型)

hz-0107P Beta-Amyloid (1-42)  β淀粉样肽（1-42）

Y-0044 Amyloid Beta 25-35( Beta-Amyloid 25-35)  β淀粉样肽25-35（多肽）

hz-0076P Beta-Amyloid 1-42 CT  β淀粉样肽 1-42 (C端多肽)

hz-0057P Amylin  糖尿病相关肽（胰岛淀粉样肽）

hz-0112P APP695-770 (Amyloid protein precursor)  淀粉样肽前体蛋白（多肽抗原）

hz-0499P Neuroprotective peptide/Gly-HN(Nuclear-encoded Humanin [HN(N)] Gly14)  神经保护肽

Y-0158 Amylin(1-37) amide  糖尿病相关肽/胰岛淀粉样肽

hz-1053P CCP peptide (cyclic citrullinated peptide,CCP)   瓜氨酸环肽

hz-0616P CCP peptide (cyclic citrullinated peptide,CCP)  瓜氨酸环肽

hz-4536P Streptococcus suis 2 (Cell protein)  2型猪链球菌菌体蛋白

hz-0038P GLP-1(Glucagon-like peptide-1)(7-36)peptide  胰高血糖素样肽-1（多肽）

hz-0995P ADM (Adrenomedullin)ProAM-N20 Rat, human, mo, pig, dog, bov  肾上腺髓质素蛋白(N端20肽)

hz-1158P AGEs  晚期糖基化终末产物AGEs

hz-1158Phz AGEs control article(advanced glycosylation end products control article)  晚期糖基化终末产物蛋白对照品

hz-0954P ET-1(Endothelin-1)  内皮素-1（蛋白多肽 活性蛋白）

Y-0108 GRGDS peptide  粘附多肽GRGDS

hz-0601P PACAP(1-38 Peptide)  腺苷酸环化酶激活肽 1-38（全蛋白）

hz-0380P MBP(Myelin Basic Protein, MBP 68-86)  髓鞘碱性蛋白(多肽抗原)

hz-2046P Bursin  囊素三肽/三肽囊素/鸡法氏囊三肽

hz-0383P NPY ( Neuropeptide Y)1-36  神经肽 Y（1-36多肽）

Y-0067 Leupeptin   亮抑酶肽

hz-0011P GRP( Gastrin Releasing Peptide )  促胃泌素释放肽（抗原）

P0006 BSA(标准)  牛血清白蛋白（标准）