RNA结合蛋白片段Y染色体家族蛋白2抗体

英文名称    RBMY1F    

中文名称    RNA结合蛋白片段Y染色体家族蛋白2抗体    

别    名    YRRM2; RNA binding motif protein, Y chromosome, family 1 member F/J; RNA binding motif protein, Y linked, family 1, member F; Y chromosome RNA recognition motif 2; YRRM2; RBY1F_HUMAN.    

RNA结合蛋白片段Y染色体家族蛋白2抗体       

说 明 书    0.2ml      

研究领域    细胞生物  发育生物学  干细胞  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    56kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from Human RBMY1F    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

RNA结合蛋白片段Y染色体家族蛋白2抗体 产品介绍    background:
The RBM (RNA-binding motif) gene family encodes proteins with an RNA binding motif. RBMY (RBM, Y chromosome) encodes a germ-cell specific nuclear protein involved in spermatogenesis. The RBM gene family, including RBMY1A, RBMY1B, RBMY1D, RBMY1E, RBMY1F, RBMY1H and RBMY1J, is comprised of at least 30 genes and pseudogenes, found on both arms of the Y chromosome. RBM X, an ancestral X chromosome homolog of the RBMY gene, encodes hnRNP G, which is widely expressed, whereas the RBMY gene evolved a male-specific function in spermatogenesis. Micro-deletions of the AZFb region of the Y chromosome, which contains a number of RBMY genes, usually result in severe consequences for spermatogenesis. RBM expression is localized to the nuclei of germ cells and RBM interacts with Tra2beta. Tra2beta is a ubiquitous activator of pre-mRNA splicing, but is most highly expressed in testis, suggesting a role for RBM in Tra2beta-dependent splicing in spermatocytes. The human RBMX gene maps to chromosome Xq26 and the RBMY gene family is found on all mammalian Y chomosomes.

Function:
RBMY1F is an RNA binding protein which may be involved in spermatogenesis. It is required for sperm development, possibly by participating in pre mRNA splicing in the testis. The RBMY1 proteins are encoded by strongly repeated regions of the Y chromosome, mostly within the AZFb region. The exact number of functional copies is unclear and may vary between individuals, and some of them may represent pseudogenes. The proteins are very similar, and most experimental data does not discriminate between the different members. 

Subunit:
Interacts with splicing factor proteins SFRS3/SRP20, TRA2B/SFRS10, KHDRBS1/SAM68 and KHDRBS3. 

Subcellular Location:
Nuclear

Tissue Specificity:
Testis-specific. 

Similarity:
Contains 1 RRM (RNA recognition motif) domain. 

Database links:
UniProtKB/Swiss-Prot: Q15415.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

RNA结合蛋白片段Y染色体家族蛋白2抗体 

hz-0358D-AF647 Donkey Anti-Guinea pig IgG/Alexa Fluor 647  Alexa Fluor 647标记的驴抗豚鼠IgG

hz-0358D-PE-hzy5.5 Donkey Anti-Guinea pig IgG/PE-Cy5.5  PE-Cy5.5标记的驴抗豚鼠IgG

hz-0358D-PE-hzy7 Donkey Anti-Guinea pig IgG/PE-Cy7  PE-Cy7标记的驴抗豚鼠IgG

hz-0358D-FIThz Donkey Anti-Guinea pig IgG/FITC  FITC标记的驴抗豚鼠IgG

hz-0358D-RBIThz Donkey Anti-Guinea pig IgG/RBITC  罗丹明标记的驴抗豚鼠IgG

hzm-0297M-RBIThz Mouse Anti-human IgG(3D3)/RBITC  罗丹明标记的鼠抗人IgG单克隆抗体

hzm-0297M-FIThz Mouse Anti-human IgG(3D3)/FITC  FITC标记的鼠抗人IgG单克隆抗体

hzm-0297M-Gold Mouse Anti-human IgG(3D3)/Gold  胶体金标记的鼠抗人IgG单克隆抗体

hzm-0297M-hzy3 Mouse Anti-human IgG(3D3)/Cy3  Cy3标记的鼠抗人IgG单克隆抗体

hzm-0297M-hzy5 Mouse Anti-human IgG(3D3)/Cy5  Cy5标记的鼠抗人IgG单克隆抗体

hzm-0297M-hzy5.5 Mouse Anti-human IgG(3D3)/Cy5.5  Cy5.5标记的鼠抗人IgG单克隆抗体

hzm-0297M-hzy7 Mouse Anti-human IgG(3D3)/Cy7  Cy7标记的鼠抗人IgG单克隆抗体

hzm-0297M-PE Mouse Anti-human IgG(3D3)/PE  PE标记的鼠抗人IgG单克隆抗体

hzm-0297M-PE-hzy3 Mouse Anti-human IgG(3D3)/PE-Cy3  PE-Cy3标记的鼠抗人IgG单克隆抗体

hzm-0297M-PE-hzY5 Mouse Anti-human IgG(3D3)/PE-CY5  PE-CY5标记的鼠抗人IgG单克隆抗体

hzm-0297M-APhz Mouse Anti-human IgG(3D3)/APC  APC标记的鼠抗人IgG单克隆抗体

hzm-0297M-AF350 Mouse Anti-human IgG(3D3)/Alexa Fluor 350  Alexa Fluor 350标记的鼠抗人IgG单克隆抗体

hzm-0297M-AF488 Mouse Anti-human IgG(3D3)/Alexa Fluor 488  Alexa Fluor 488标记的鼠抗人IgG单克隆抗体

hzm-0297M-AF555 Mouse Anti-human IgG(3D3)/Alexa Fluor 555  Alexa Fluor 555标记的鼠抗人IgG单克隆抗体

hzm-0297M-AF647 Mouse Anti-human IgG(3D3)/Alexa Fluor 647  Alexa Fluor 647标记的鼠抗人IgG单克隆抗体

hzm-0297M-PE-hzy5.5 Mouse Anti-human IgG(3D3)/PE-Cy5.5  PE-Cy5.5标记的鼠抗人IgG单克隆抗体

hzm-0297M-PE-hzy7 Mouse Anti-human IgG(3D3)/PE-Cy7  PE-Cy7标记的鼠抗人IgG单克隆抗体

hzm-0297M-HRP Mouse Anti-human IgG(3D3)/HRP  辣根过氧化物酶标记的鼠抗人IgG单克隆抗体

hzm-0297M-AP Mouse Anti-human IgG(3D3)/AP  碱性磷酸酶（AP）标记的鼠抗人IgG单克隆抗体

hzm-0297M-Bio Mouse Anti-human IgG(3D3)/Bio  生物素标记的鼠抗人IgG单克隆抗体

五、蛋白质与多肽

编  号 名  称

hz-0292P BSA (bovine serum albumin)  牛血清白蛋白（第五组分）

hz-0225P KLH (keyhole limpet hhzocyanin)  血蓝蛋白

hz-0283P OVA (ovalbumin)  鸡卵白蛋白

hz-0291P THY (thyroglobulin,TG)  甲状腺球蛋白

hz-0945P HSA/human Serum albumin  人血清白蛋白

hz-1240P Hu Fibrinogen  人纤维蛋白原

hz-0437P Streptavidin, SA  链霉亲和素

PH-2 Protein G/FITC  FITC标记蛋白-G