RNA结合蛋白片段Y染色体家族蛋白1抗体

英文名称    RBMY1A1    

中文名称    RNA结合蛋白片段Y染色体家族蛋白1抗体    

别    名    hRBMY; MGC181956; RBM1; RBM2; RBMY; RNA binding motif protein 1; RNA binding motif protein 2; RNA binding motif protein Y chromosome family 1 member A1; RNA binding motif protein Y chromosome family 1 member A1/C; RNA binding motif protein Y chromosome family 1 member; RNA binding motif protein Y linked family 1 member A1; Y chromosome RNA recognition motif 1; YRRM1; YRRM2; RBY1A_HUMAN.    

RNA结合蛋白片段Y染色体家族蛋白1抗体 

说 明 书    

研究领域    发育生物学  干细胞  结合蛋白  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Cow, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    56kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from Human RBMY1A1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

RNA结合蛋白片段Y染色体家族蛋白1抗体产品介绍    background:
The RBM (RNA-binding motif) gene family encodes proteins with an RNA binding motif. RBMY (RBM, Y chromosome) encodes a germ-cell specific nuclear protein involved in spermatogenesis. The RBM gene family, including RBMY1A, RBMY1B, RBMY1D, RBMY1E, RBMY1F, RBMY1H and RBMY1J, is comprised of at least 30 genes and pseudogenes, found on both arms of the Y chromosome. RBM X, an ancestral X chromosome homolog of the RBMY gene, encodes hnRNP G, which is widely expressed, whereas the RBMY gene evolved a male-specific function in spermatogenesis. Micro-deletions of the AZFb region of the Y chromosome, which contains a number of RBMY genes, usually result in severe consequences for spermatogenesis. RBM expression is localized to the nuclei of germ cells and RBM interacts with Tra2beta. Tra2beta is a ubiquitous activator of pre-mRNA splicing, but is most highly expressed in testis, suggesting a role for RBM in Tra2beta-dependent splicing in spermatocytes. The human RBMX gene maps to chromosome Xq26 and the RBMY gene family is found on all mammalian Y chomosomes. 

Function:
RBMY1A1 is an RNA-binding protein which may be involved in spermatogenesis. It is required for sperm development, possibly by participating in pre-mRNA splicing in the testis. 

Subunit:
Interacts with splicing factor proteins SFRS3/SRP20, TRA2B/SFRS10, KHDRBS1/SAM68 and KHDRBS3. 

Subcellular Location:
Nuclear

Tissue Specificity:
Testis-specific. 

Similarity:
Contains 1 RRM (RNA recognition motif) domain. 

Database links:
UniProtKB/Swiss-Prot: P0DJD3.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

RNA结合蛋白片段Y染色体家族蛋白1抗体

hz-0294D-Gold Donkey Anti-Goat IgG/Gold  胶体金标记的驴抗羊IgG

hz-0294D-FIThz Donkey Anti-Goat IgG/FITC  FITC标记的驴抗羊IgG

hz-0294D-AP Donkey Anti-Goat IgG/AP  碱性磷酸酶（AP）标记的驴抗羊IgG

hz-0294D-AF555 Donkey Anti-Goat IgG/Alexa Fluor 555  Alexa Fluor 555标记的驴抗羊IgG

hz-0294D-AF647 Donkey Anti-Goat IgG/Alexa Fluor 647  Alexa Fluor 647标记的驴抗羊IgG

hz-0294D-PE-hzy5.5 Donkey Anti-Goat IgG/PE-Cy5.5  PE-Cy5.5标记的驴抗羊IgG

hz-0294D-PE-hzy7 Donkey Anti-Goat IgG/PE-Cy7  PE-Cy7标记的驴抗羊IgG

hz-0294D-HRP Donkey Anti-Goat IgG/HRP  辣根过氧化物酶标记的驴抗羊IgG

hz-0294D-hzy3 Donkey Anti-Goat IgG/Cy3  Cy3标记的驴抗羊IgG

hz-0294D-hzy5 Donkey Anti-Goat IgG/Cy5  Cy5标记的驴抗羊IgG

hz-0294D-hzy5.5 Donkey Anti-Goat IgG/Cy5.5  Cy5.5标记的驴抗羊IgG

hz-0294D-hzy7 Donkey Anti-Goat IgG/Cy7  Cy7标记的驴抗羊IgG

hz-0294D-PE Donkey Anti-Goat IgG/PE  PE标记的驴抗羊IgG

hz-0294D-PE-hzy3 Donkey Anti-Goat IgG/PE-Cy3  PE-Cy3标记的驴抗羊IgG

hz-0294D-PE-hzY5 Donkey Anti-Goat IgG/PE-CY5  PE-CY5标记的驴抗羊IgG

hz-0294D-APhz Donkey Anti-Goat IgG/APC  APC标记的驴抗羊IgG

hz-0294D-AF350 Donkey Anti-Goat IgG/Alexa Fluor 350  Alexa Fluor 350标记的驴抗羊IgG

hz-0294D-AF488 Donkey Anti-Goat IgG/Alexa Fluor 488  Alexa Fluor 488标记的驴抗羊IgG

hz-0294D-RBIThz Donkey Anti-Goat IgG/RBITC  罗丹明标记的驴抗羊IgG

hz-0294D-Bio Donkey Anti-Goat IgG/Bio  生物素标记的驴抗羊IgG

hz-0358D-Gold Donkey Anti-Guinea pig IgG/Gold  胶体金标记的驴抗豚鼠IgG

hz-0358D-HRP Donkey Anti-Guinea pig IgG/HRP  辣根过氧化物酶标记的驴抗豚鼠IgG

hz-0358D-Bio Donkey Anti-Guinea pig IgG/Bio  生物素标记的驴抗豚鼠IgG

hz-0358D-AP Donkey Anti-Guinea pig IgG/AP  碱性磷酸酶（AP）标记的驴抗豚鼠IgG

hz-0358D-hzy3 Donkey Anti-Guinea pig IgG/Cy3  Cy3标记的驴抗豚鼠IgG

hz-0358D-hzy5 Donkey Anti-Guinea pig IgG/Cy5  Cy5标记的驴抗豚鼠IgG

hz-0358D-hzy5.5 Donkey Anti-Guinea pig IgG/Cy5.5  Cy5.5标记的驴抗豚鼠IgG

hz-0358D-hzy7 Donkey Anti-Guinea pig IgG/Cy7  Cy7标记的驴抗豚鼠IgG

hz-0358D-PE Donkey Anti-Guinea pig IgG/PE  PE标记的驴抗豚鼠IgG

hz-0358D-PE-hzy3 Donkey Anti-Guinea pig IgG/PE-Cy3  PE-Cy3标记的驴抗豚鼠IgG

hz-0358D-PE-hzY5 Donkey Anti-Guinea pig IgG/PE-CY5  PE-CY5标记的驴抗豚鼠IgG

hz-0358D-APhz Donkey Anti-Guinea pig IgG/APC  APC标记的驴抗豚鼠IgG

hz-0358D-AF350 Donkey Anti-Guinea pig IgG/Alexa Fluor 350  Alexa Fluor 350标记的驴抗豚鼠IgG

hz-0358D-AF488 Donkey Anti-Guinea pig IgG/Alexa Fluor 488  Alexa Fluor 488标记的驴抗豚鼠IgG

hz-0358D-AF555 Donkey Anti-Guinea pig IgG/Alexa Fluor 555  Alexa Fluor 555标记的驴抗豚鼠IgG