受体活性修饰蛋白2抗体

英文名称    RAMP2    

中文名称    受体活性修饰蛋白2抗体    

别    名    Calcitonin receptor like receptor activity modifying protein 2; CRLR activity modifying protein 2; OTTMUSP00000002615; OTTMUSP00000037624; Receptor (calcitonin) activity modifying protein 2; Receptor activity modifying protein 2; Receptor activity modifying protein 2 isoform; RP23-281C18.6; RAMP2_HUMAN.    

受体活性修饰蛋白2抗体         

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞生物  信号转导  生长因子和激素  细胞膜受体  G蛋白偶联受体  G蛋白信号  细胞膜蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    15kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RAMP2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

受体活性修饰蛋白2抗体 产品介绍    background:
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.

Function:
RAMP2 (Receptor activity-modifying protein 2) transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. RAMP2 acts as a receptor for adrenomedullin (AM) together with CALCRL. Co-expression of Receptor activity-modifying protein 2 (RAMP2) with the calcitonin-receptor-like-receptor (CRLR) results in the production of a functional adrenomedullin (ADM) receptor. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. RAMP2 is a heterodimer of CALCRL and RAMP2. RAMP2 is strongly expressed in lung, breast, immune system and fetal tissues. RAMP2 belongs to the RAMP family.

Subunit:
Heterodimer of CALCRL and RAMP2

Subcellular Location:
Cell Membrane; Single-pass type I membrane protein

Tissue Specificity:
Strongly expressed in lung, breast, immune system and fetal tissues.

Similarity:
Belongs to the RAMP family. 

Database links:
UniProtKB/Swiss-Prot: O60895.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

受体活性修饰蛋白2抗体 

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hz-0336R-AF647 Rabbit Anti-MK IgM/Alexa Fluor 647  Alexa Fluor 647标记的兔抗猴IgM

hz-0336R-PE-hzy5.5 Rabbit Anti-MK IgM/PE-Cy5.5  PE-Cy5.5标记的兔抗猴IgM

hz-0336R-PE-hzy7 Rabbit Anti-MK IgM/PE-Cy7  PE-Cy7标记的兔抗猴IgM

hz-0336R-Bio Rabbit Anti-Monkey IgM/Bio  生物素标记的兔抗猴IgM

hz-0336R-AP Rabbit Anti-Monkey IgM/AP  碱性磷酸酶（AP）标记的兔抗猴IgM

hz-0336R-Gold Rabbit Anti-Monkey IgM/Gold  胶体金标记的兔抗猴IgM

hz-0336R-HRP Rabbit Anti-Monkey IgM/HRP  辣根过氧化物酶标记的兔抗猴IgM

hz-0336R-PE-hzy3 Rabbit Anti-Monkey IgM/PE-Cy3  PE-Cy3标记的兔抗猴IgM

hz-0336R-PE-hzY5 Rabbit Anti-Monkey IgM/PE-CY5  PE-CY5标记的兔抗猴IgM

hz-0336R-FIThz Rabbit Anti-Monkey IgM/FITC  FITC标记的兔抗猴IgM

hz-0336R-RBIThz Rabbit Anti-Monkey IgM/RBITC  罗丹明标记的兔抗猴IgM

hz-0296R-RBIThz Rabbit Anti-mouse IgG/RBITC  罗丹明标记的兔抗小鼠IgG

hz-0296R-FIThz Rabbit Anti-mouse IgG/FITC  FITC标记的兔抗小鼠IgG

hz-0296R-Gold Rabbit Anti-mouse IgG/Gold  胶体金标记的兔抗小鼠IgG

hz-0296R-HRP Rabbit Anti-mouse IgG/HRP  辣根过氧化物酶标记的兔抗小鼠IgG

hz-0296R-AP Rabbit Anti-mouse IgG/AP  碱性磷酸酶（AP）标记的兔抗小鼠IgG

hz-0296R-Bio Rabbit Anti-mouse IgG/Bio  生物素标记的兔抗小鼠IgG

hz-0296R-hzy3 Rabbit Anti-mouse IgG/Cy3  Cy3标记的兔抗小鼠IgG

hz-0296R-hzy5.5 Rabbit Anti-mouse IgG/Cy5.5  Cy5.5标记的兔抗小鼠IgG

hz-0296R-hzy7 Rabbit Anti-mouse IgG/Cy7  Cy7标记的兔抗小鼠IgG

hz-0296R-PE Rabbit Anti-mouse IgG/PE  PE标记的兔抗小鼠IgG

hz-0296R-PE-hzy3 Rabbit Anti-mouse IgG/PE-Cy3  PE-Cy3标记的兔抗小鼠IgG

hz-0296R-PE-hzY5 Rabbit Anti-mouse IgG/PE-CY5  PE-CY5标记的兔抗小鼠IgG

hz-0296R-APhz Rabbit Anti-mouse IgG/APC  APC标记的兔抗小鼠IgG

hz-0296R-AF350 Rabbit Anti-mouse IgG/Alexa Fluor 350  Alexa Fluor 350标记的兔抗小鼠IgG

hz-0296R-AF488 Rabbit Anti-mouse IgG/Alexa Fluor 488  Alexa Fluor 488标记的兔抗小鼠IgG

hz-0296R-AF555 Rabbit Anti-mouse IgG/Alexa Fluor 555  Alexa Fluor 555标记的兔抗小鼠IgG

hz-0296R-AF647 Rabbit Anti-mouse IgG/Alexa Fluor 647  Alexa Fluor 647标记的兔抗小鼠IgG

hz-0296R-PE-hzy5.5 Rabbit Anti-mouse IgG/PE-Cy5.5  PE-Cy5.5标记的兔抗小鼠IgG

hz-0296R-PE-hzy7 Rabbit Anti-mouse IgG/PE-Cy7  PE-Cy7标记的兔抗小鼠IgG

hz-0368R-Bio Rabbit Anti-mouse IgM/Bio  生物素标记的兔抗小鼠IgM

hz-0368R-HRP Rabbit Anti-mouse IgM/HRP  辣根过氧化物酶标记的兔抗小鼠IgM

hz-0368R-Gold Rabbit Anti-mouse IgM/Gold  胶体金标记的兔抗小鼠IgM

hz-0368R-AP Rabbit Anti-mouse IgM/AP  碱性磷酸酶（AP）标记的兔抗小鼠IgM

hz-0368R-hzy5 Rabbit Anti-mouse IgM/Cy5  Cy5标记的兔抗小鼠IgM

hz-0368R-hzy5.5 Rabbit Anti-mouse IgM/Cy5.5  Cy5.5标记的兔抗小鼠IgM

hz-0368R-hzy7 Rabbit Anti-mouse IgM/Cy7  Cy7标记的兔抗小鼠IgM