英文名称 RPS7
中文名称 核糖体蛋白S7抗体
别 名 40S ribosomal protein S7; DBA8; Ribosomal protein S7; RPS 7; rps7; RS7_HUMAN; S7.
核糖体蛋白S7抗体
说 明 书 0.2ml
研究领域 细胞生物 免疫学 信号转导 转录调节因子 激酶和磷酸酶 表观遗传学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
细胞定位 细胞核 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human RPS7
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
核糖体蛋白S7抗体产品介绍 background:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Function:
Required for rRNA maturation.
DISEASE:
Defects in RPS7 are the cause of Diamond-Blackfan anemia type 8 (DBA8) [MIM:612563]. DBA8 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
Similarity:
Belongs to the ribosomal protein S7e family.
Database links:
Entrez Gene: 505507 Cow
Entrez Gene: 6201 Human
Entrez Gene: 20115 Mouse
Entrez Gene: 29258 Rat
Entrez Gene: 393725 Zebrafish
Omim: 603658 Human
SwissProt: A6H769 Cow
SwissProt: P62081 Human
SwissProt: P62082 Mouse
SwissProt: P62083 Rat
SwissProt: P62084 Zebrafish
Unigene: 7187 Cow
Unigene: 534346 Human
Unigene: 546287 Human
Unigene: 646582 Human
Unigene: 279839 Mouse
Unigene: 371579 Mouse
Unigene: 107039 Rat
Unigene: 224475 Rat
Unigene: 28230 Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核糖体蛋白S7抗体
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