核糖体蛋白S7抗体

英文名称    RPS7    

中文名称    核糖体蛋白S7抗体    

别    名    40S ribosomal protein S7; DBA8; Ribosomal protein S7; RPS 7; rps7; RS7_HUMAN; S7.    

核糖体蛋白S7抗体       

说 明 书    0.2ml      

研究领域    细胞生物  免疫学  信号转导  转录调节因子  激酶和磷酸酶  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    22kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RPS7    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

核糖体蛋白S7抗体产品介绍    background:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Function:
Required for rRNA maturation.

DISEASE:
Defects in RPS7 are the cause of Diamond-Blackfan anemia type 8 (DBA8) [MIM:612563]. DBA8 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.

Similarity:
Belongs to the ribosomal protein S7e family.

Database links:

Entrez Gene: 505507 Cow

Entrez Gene: 6201 Human

Entrez Gene: 20115 Mouse

Entrez Gene: 29258 Rat

Entrez Gene: 393725 Zebrafish

Omim: 603658 Human

SwissProt: A6H769 Cow

SwissProt: P62081 Human

SwissProt: P62082 Mouse

SwissProt: P62083 Rat

SwissProt: P62084 Zebrafish

Unigene: 7187 Cow

Unigene: 534346 Human

Unigene: 546287 Human

Unigene: 646582 Human

Unigene: 279839 Mouse

Unigene: 371579 Mouse

Unigene: 107039 Rat

Unigene: 224475 Rat

Unigene: 28230 Zebrafish

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

核糖体蛋白S7抗体

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