丝氨酸/精氨酸相关蛋白53抗体

英文名称    RSRC1/SRrp53    

中文名称    丝氨酸/精氨酸相关蛋白53抗体    

别    名    1200013F24Rik; Arginine/serine rich coiled coil 1; Arginine/serine-rich coiled-coil protein 1; BM 011; MGC103357; MGC12197; OTTHUMP00000213444; OTTHUMP00000213446; OTTHUMP00000213451; RGD1304968; Rsrc1; RSRC1_HUMAN; Serine/Arginine-related protein 53; SFRS21; Splicing factor arginine/serine rich 21; SRrp53.    

丝氨酸/精氨酸相关蛋白53抗体        

说 明 书    0.2ml      

研究领域    细胞生物  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Cat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    38kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RSRC1/SRrp53    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

丝氨酸/精氨酸相关蛋白53抗体产品介绍    background:
This gene encodes a member of the serine and arginine rich-related protein family. The encoded protein is involved in both constitutive and alternative mRNA splicing. This gene may be associated with schizophrenia. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]

Function:
Plays a role in pre-mRNA splicing. Involved in both constitutive and alternative pre-mRNA splicing. May have a role in the recognition of the 3' splice site during the second step of splicing.

Subcellular Location:
Nucleus. Nucleus speckle. Cytoplasm. Shuttles between the nucleus and cytoplasm.

Post-translational modifications:
Phosphorylated.

Database links:

Entrez Gene: 51319 Human

Entrez Gene: 66880 Mouse

Entrez Gene: 361956 Rat

Omim: 613352 Human

SwissProt: Q96IZ7 Human

SwissProt: Q9DBU6 Mouse

SwissProt: Q5PPJ2 Rat

Unigene: 591283 Human

Unigene: 316418 Mouse

Unigene: 73117 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

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