肺表面活性蛋白D抗体

英文名称    SFTPD    

中文名称    肺表面活性蛋白D抗体    

别    名    SFTPD surfactant protein D; pulmonary surfactant-associated glycoprotein D; COLEC 7; COLEC7; Collectin7; PSP D; PSPD; Pulmonary surfactant apoprotein; Pulmonary surfactant associated protein D; SFTP 4; SFTP4; SFTPD; SP D; Surfactant associated protein pulmonary 4; Surfactant pulmonary associated protein D; SFTPD_HUMAN; Pulmonary surfactant-associated protein D; PSP-D; SP-D; Collectin-7; Lung surfactant protein D.    

肺表面活性蛋白D抗体       

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  免疫学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    41kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human SP-D    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

肺表面活性蛋白D抗体产品介绍    background:
Surfactant protein D contributes to the lung's defense against inhaled microorganisms. It's a calcium ion dependent carbohydrate binding protein and is structurally similar to other C type mammalian lectins, such as conglutinin and SPA. It has a molecular size of approximately 37-43kDa in its reduced state, 620kDa in non dissociating conditions. Surfactant protein D enhances the production of oxygen radicals by rat alveolar macrophages and regulates some actions of SPA, which is the most abundant surfactant protein. Surfactant protein D is synthesized and secreted by alveolar epithelial type II cells.

Function:
Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

Subunit:
Oligomeric complex of 4 set of homotrimers.

Subcellular Location:
Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film.

Post-translational modifications:
The N-terminus is blocked. 
Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.

Similarity:
Belongs to the SFTPD family. 
Contains 1 C-type lectin domain. 
Contains 1 collagen-like domain.

Gene ID:
6441

Database links:

Entrez Gene: 6441 Human

Entrez Gene: 20390 Mouse

Entrez Gene: 25350 Rat

Omim: 178635 Human

SwissProt: P35247 Human

SwissProt: P50404 Mouse

SwissProt: P35248 Rat

Unigene: 253495 Human

Unigene: 1321 Mouse

Unigene: 11348 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

肺表面活性蛋白D抗体

hz-0326M-FIThz Mouse Anti-Bov IgG/FITC  FITC标记的小鼠抗牛IgG

hz-0326M-hzy5 Mouse Anti-Bov IgG/Cy5  Cy5标记的小鼠抗牛IgG

hz-0326M-hzy5.5 Mouse Anti-Bov IgG/Cy5.5  Cy5.5标记的小鼠抗牛IgG

hz-0326M-hzy7 Mouse Anti-Bov IgG/Cy7  Cy7标记的小鼠抗牛IgG

hz-0326M-PE Mouse Anti-Bov IgG/PE  PE标记的小鼠抗牛IgG

hz-0326M-PE-hzy3 Mouse Anti-Bov IgG/PE-Cy3  PE-Cy3标记的小鼠抗牛IgG

hz-0326M-PE-hzY5 Mouse Anti-Bov IgG/PE-CY5  PE-CY5标记的小鼠抗牛IgG

hz-0326M-APhz Mouse Anti-Bov IgG/APC  APC标记的小鼠抗牛IgG

hz-0326M-AF350 Mouse Anti-Bov IgG/Alexa Fluor 350  Alexa Fluor 350标记的小鼠抗牛IgG

hz-0326M-AF488 Mouse Anti-Bov IgG/Alexa Fluor 488  Alexa Fluor 488标记的小鼠抗牛IgG

hz-0326M-AF555 Mouse Anti-Bov IgG/Alexa Fluor 555  Alexa Fluor 555标记的小鼠抗牛IgG

hz-0326M-AF647 Mouse Anti-Bov IgG/Alexa Fluor 647  Alexa Fluor 647标记的小鼠抗牛IgG

hz-0326M-PE-hzy5.5 Mouse Anti-Bov IgG/PE-Cy5.5  PE-Cy5.5标记的小鼠抗牛IgG

hz-0358M-hzy3 Mouse Anti-Guinea pig IgG/Cy3  Cy3标记的小鼠抗豚鼠IgG

hz-0358M-hzy5 Mouse Anti-Guinea pig IgG/Cy5  Cy5标记的小鼠抗豚鼠IgG

hz-0358M-hzy5.5 Mouse Anti-Guinea pig IgG/Cy5.5  Cy5.5标记的小鼠抗豚鼠IgG

hz-0358M-hzy7 Mouse Anti-Guinea pig IgG/Cy7  Cy7标记的小鼠抗豚鼠IgG

hz-0358M-PE Mouse Anti-Guinea pig IgG/PE  PE标记的小鼠抗豚鼠IgG

hz-0358M-PE-hzy3 Mouse Anti-Guinea pig IgG/PE-Cy3  PE-Cy3标记的小鼠抗豚鼠IgG

hz-0358M-PE-hzY5 Mouse Anti-Guinea pig IgG/PE-CY5  PE-CY5标记的小鼠抗豚鼠IgG

hz-0358M-FIThz Mouse Anti-Guinea pig IgG/FITC  FITC标记的小鼠抗豚鼠IgG

hz-0358M-RBIThz Mouse Anti-Guinea pig IgG/RBITC  罗丹明标记的小鼠抗豚鼠IgG

hz-0358M-AP Mouse Anti-Guinea pig IgG/AP  碱性磷酸酶（AP）标记的小鼠抗豚鼠IgG

hz-0358M-Bio Mouse Anti-Guinea pig IgG/Bio  生物素标记的小鼠抗豚鼠IgG

hz-0358M-Gold Mouse Anti-Guinea pig IgG/Gold  胶体金标记的小鼠抗豚鼠IgG

hz-0358M-HRP Mouse Anti-Guinea pig IgG/HRP  辣根过氧化物酶标记的小鼠抗豚鼠IgG

hz-0358M-APhz Mouse Anti-Guinea pig IgG/APC  APC标记的小鼠抗豚鼠IgG

hz-0358M-AF350 Mouse Anti-Guinea pig IgG/Alexa Fluor 350  Alexa Fluor 350标记的小鼠抗豚鼠IgG

hz-0358M-AF488 Mouse Anti-Guinea pig IgG/Alexa Fluor 488  Alexa Fluor 488标记的小鼠抗豚鼠IgG

hz-0358M-AF555 Mouse Anti-Guinea pig IgG/Alexa Fluor 555  Alexa Fluor 555标记的小鼠抗豚鼠IgG

hz-0358M-AF647 Mouse Anti-Guinea pig IgG/Alexa Fluor 647  Alexa Fluor 647标记的小鼠抗豚鼠IgG

hz-0358M-PE-hzy5.5 Mouse Anti-Guinea pig IgG/PE-Cy5.5  PE-Cy5.5标记的小鼠抗豚鼠IgG

hz-0358M-PE-hzy7 Mouse Anti-Guinea pig IgG/PE-Cy7  PE-Cy7标记的小鼠抗豚鼠IgG

hz-0312R-hzy3 Rabbit Anti-Avidin/Cy3  Cy3标记的兔抗亲和素

hz-0312R-hzy5 Rabbit Anti-Avidin/Cy5  Cy5标记的兔抗亲和素

hz-0312R-hzy5.5 Rabbit Anti-Avidin/Cy5.5  Cy5.5标记的兔抗亲和素

hz-0312R-Bio Rabbit Anti-Avidin/Bio  生物素标记的兔抗亲和素

hz-0312R-AP Rabbit Anti-Avidin/AP  碱性磷酸酶（AP）标记的兔抗亲和素

hz-0312R-HRP Rabbit Anti-Avidin/HRP  辣根过氧化物酶标记的兔抗亲和素

hz-0312R-hzy7 Rabbit Anti-Avidin/Cy7  Cy7标记的兔抗亲和素

hz-0312R-PE Rabbit Anti-Avidin/PE  PE标记的兔抗亲和素

hz-0312R-PE-hzy3 Rabbit Anti-Avidin/PE-Cy3  PE-Cy3标记的兔抗亲和素

hz-0312R-RBIThz Rabbit Anti-Avidin/RBITC  罗丹明标记的兔抗亲和素

hz-0312R-Gold Rabbit Anti-Avidin/Gold  胶体金标记的兔抗亲和素

hz-0312R-FIThz Rabbit Anti-Avidin/FITC  FITC标记的兔抗亲和素