钙结合样蛋白/神经内分泌肿瘤标记物抗体

英文名称    SCGN    

中文名称    钙结合样蛋白/神经内分泌肿瘤标记物抗体    

别    名    Calbindin like; CALBL; DJ501N12.8; Scgn; SECRET; Secretagogin; Secretagogin EF hand calcium binding protein; SEGN; SEGN_HUMAN; Setagin.    

钙结合样蛋白/神经内分泌肿瘤标记物抗体        

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞生物  神经生物学  肿瘤细胞生物标志物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    32kDa    

细胞定位    细胞浆 细胞膜 分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Secretagogin (221-276aa)    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

钙结合样蛋白/神经内分泌肿瘤标记物抗体产品介绍    background:
The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation. [provided by RefSeq, Jul 2008]

Subcellular Location:
Cytoplasm. Secreted. Cytoplasmic vesicle > secretory vesicle membrane. Predominantly cytoplasmic. A small proportion is associated with secretory granules and membrane fractions (By similarity). Detectable in human serum after ischemic neuronal damage.

Tissue Specificity:
Expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression is restricted to distinct subtypes of neurons with highest expression in the molecular layer of the cerebellum (stellate and basket cells), in the anterior part of the pituitary gland, in the thalamus, in the hypothalamus and in a subgroup of neocortical neurons.

Similarity:
Contains 6 EF-hand domains.

Gene ID:
10590

Database links:

Entrez Gene: 10590 Human

Entrez Gene: 306942 Rat

Omim: 609202 Human

SwissProt: O76038 Human

SwissProt: Q6R556 Rat

Unigene: 116428 Human

Unigene: 53156 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

钙结合样蛋白/神经内分泌肿瘤标记物抗体

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hz-5322R phospho-EGFR (Ser1142)  磷酸化表皮生长因子受体抗体

hz-5333R phospho-EGFR (Ser967)  磷酸化表皮生长因子受体抗体

hz-2010R EGF  表皮生长因子抗体（大鼠）

hz-1755R EGFL7  类表皮生长因子域7抗体

hz-5877R MUC13  粘蛋白13抗体

hz-0405R EGFR  表皮生长因子受体抗体

hz-5878R MUC15  粘蛋白15抗体

hz-2503R EF1a  翻译延伸因子EF-1a抗体

hz-2558R EGFRvIII  表皮生长因子受体III型突变体抗体

hz-1076R Egr1  早期生长应答蛋白1抗体

hz-5879R MUC7  粘蛋白7抗体

hz-5880R CDCP1/CD318  CD318抗体

hz-4103R EIF4B  真核翻译起始因子4B抗体

hz-5345R phospho-EIF4B (Ser422)  磷酸化真核翻译起始因子4B抗体

hz-5346R phospho-EIF4B (Ser540)  磷酸化真核翻译起始因子4B抗体

hz-3613R eIF2 alpha  真核启动因子2α抗体(eIFα2)

hz-3488R Phospho-eIF2 alpha (Ser51)  磷酸化真核启动因子2α抗体

hz-3621R eIF4E  真核翻译起始因子4E抗体

hz-2446R phospho-eIF4E(Ser209)  磷酸化真核翻译起始因子4E抗体

hz-3840R eIF3A  真核翻译起始因子3A抗体

hz-3841R eIF3F  真核翻译起始因子3F抗体

hz-4003R phospho-eIF4G(ser1108)  磷酸化真核翻译起始因子4G抗体

hz-3843R eIF4G  真核翻译起始因子4G抗体

hz-5347R phospho-EIF4G1(Ser1238)  磷酸化真核翻译起始因子4G抗体

hz-3842R eIF3H  真核翻译起始因子3H抗体

hz-1398R ELK1  细胞转录因子ELK1抗体

hz-3175R Phospho-ELk1(Ser383)  磷酸化细胞转录因子ELK1抗体

hz-5335R Phospho-ELk1 (Ser389)  磷酸化细胞转录因子ELK1抗体

hz-5336R Phospho-ELk1(Thr417)  磷酸化细胞转录因子ELK1抗体

hz-3844R eIF6/ITGB4BP  β4整合素结合蛋白抗体

hz-4115R ITGB4  整合素β4抗体

hz-5455R phospho-ITGB4(Tyr1494)  磷酸化整合素β4抗体

hz-5456R phospho-ITGB4(Tyr1526)  磷酸化整合素β4抗体

hz-1756R Elastin  弹性蛋白α抗体

hz-2651R ELAVL1/HuR  ELAVL1抗体

hz-0558R hzp1/MUC1  表皮膜蛋白1抗体

hz-5881R COL20A1  胶原样蛋白抗体

hz-1331R sFRP-4  子宫内膜抗体

hz-0547R Endostatin/COL18A1  内皮抑素/内皮他丁抗体

hz-2800R Endo G  核酸内切酶G抗体