肿瘤细胞转移抑制蛋白抗体

英文名称    SCAI    

中文名称    肿瘤细胞转移抑制蛋白抗体    

别    名    C9orf126; FLJ11758; FLJ36664; MGC120525; MGC120526; MGC120528; NET40; Protein SCAI; SCAI; SCAI_HUMAN; Suppressor of cancer cell invasion; Suppressor of cancer cell invasion protein.    

肿瘤细胞转移抑制蛋白抗体       

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞生物  信号转导  细胞类型标志物  G蛋白信号      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    70kDa    

细胞定位    细胞核 细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human SCAI    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

肿瘤细胞转移抑制蛋白抗体产品介绍    background:
This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]

Function:
Tumor suppressor which functions to suppress MKL1-induced SRF transcriptional activity. May function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1.

Subunit:
Interacts with DIAPH1 (By similarity). Forms a nuclear ternary complex with MKL1 and SRF.

Subcellular Location:
Membrane. Nucleus. Cytoplasm. Nuclear localization is required for inhibition of MKL1.

Similarity:
Belongs to the SCAI family.

Gene ID:
286205

Database links:

Entrez Gene: 286205 Human

Entrez Gene: 320271 Mouse

Entrez Gene: 690538 Rat

SwissProt: Q8N9R8 Human

SwissProt: Q8C8N2 Mouse

Unigene: 59504 Human

Unigene: 204836 Mouse

Unigene: 206053 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

肿瘤细胞转移抑制蛋白抗体

hz-9023R IQCK  IQCK蛋白抗体

hz-9024R IQCF1  IQCF1蛋白抗体

hz-9025R ISLR2  ISLR2蛋白抗体

hz-9026R HPRT  次黄嘌呤磷酸核糖基转移酶1抗体

hz-9027R SPTLC2  丝氨酸棕榈酰转移酶2抗体

hz-9028R AKAP2  蛋白激酶A2抗体

hz-9029R PAPSS1  腺苷酸硫酸激酶1抗体

hz-9030R PAPSS2  腺苷酸硫酸激酶2抗体

hz-9031R PAS1C1  核纤层蛋白A相关结构蛋白1抗体

hz-9032R PBLD/MAWBP  MAWD结合蛋白抗体

hz-9033R PCID1  PCID1蛋白抗体

hz-9034R PCID2  PCID2蛋白抗体

hz-9035R PDXK  吡哆醛激酶抗体

hz-9036R PDZK1  PDZ结构域PDZK1蛋白抗体

hz-9037R PDZK3  前列腺癌激活蛋白抗体

hz-9038R PDZK4  PDZ结构域PDZK4蛋白抗体

hz-9039R PDZD5A/FRMPD2L2  PDZ结构域PDZK5A蛋白抗体

hz-9041R PDZD6  PDZ结构域PDZK6蛋白抗体

hz-9042R PDZD7  PDZ结构域PDZK7蛋白抗体

hz-9043R PDZD8  PDZ结构域PDZK8蛋白抗体

hz-9044R TRPM7  瞬时受体电位离子通道蛋白7抗体（M亚家族）

hz-9045R TRPM8  “冷”蛋白TRPM8抗体

hz-9046R TRPM3  瞬时受体电位离子通道蛋白3抗体（M亚家族）

hz-9047R TRPM5  瞬时受体电位离子通道蛋白5抗体（M亚家族）

hz-9048R TRPM6  瞬时受体电位离子通道蛋白6抗体（M亚家族）

hz-9049R TRPM1  瞬时受体电位离子通道蛋白1抗体（M亚家族）

hz-9051R TRPM4  瞬时受体电位离子通道蛋白4抗体（M亚家族）

hz-9052R DIS3L  有丝分裂控制样蛋白DIS3L抗体

hz-9053R DIS3L2  有丝分裂控制蛋白样DIS3L2抗体

hz-9054R DOM3Z  DOM3Z蛋白抗体

hz-9055R DR1 protein  转录下调蛋白1抗体

hz-9056R Dermokine beta  Dermokine β蛋白抗体

hz-9057R DPCR1  DPCR1蛋白抗体

hz-9058R DHFR  二氢叶酸还原酶抗体