信号肽复合物亚基2抗体

英文名称    SPCS2    

中文名称    信号肽复合物亚基2抗体    

别    名    Microsomal signal peptidase 25 kDa subunit; Signal peptidase complex subunit 2; Signal peptidase complex subunit 2 homolog (S. cerevisiae); SPase 25 kDa subunit; SPCS2; SPCS2_HUMAN.    

信号肽复合物亚基2抗体        

说 明 书    0.2ml      

研究领域    细胞生物  免疫学  信号转导      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    25kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human SPCS2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

信号肽复合物亚基2抗体产品介绍    background:
SPCS2 is a 226 amino acid multi-pass membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER), and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS2 removes signal peptides from nascent proteins as they are translocated into the lumen of the ER. The gene encoding SPCS2 is located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Function:
Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.

Subcellular Location:
Microsome membrane. Endoplasmic reticulum membrane.

Similarity:
Belongs to the SPCS2 family.

Database links:

Entrez Gene: 9789 Human

Entrez Gene: 66624 Mouse

Entrez Gene: 293142 Rat

SwissProt: Q15005 Human

SwissProt: Q9CYN2 Mouse

Unigene: 282700 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

信号肽复合物亚基2抗体

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hz-1064R KLF4  肠道内富含的Kruppel样因子/上皮锌指蛋白4抗体

hz-2385R KLF5/UKHC  驱动蛋白KIF5B抗体

hz-2303R phospho-KLF5(Ser311)  磷酸化肠道内富含的Kruppel样因子5抗体

hz-2019R phospho-KLF5(Ser272)  磷酸化KLF5抗体

hz-2020R phospho-KLF5(Ser275)  磷酸化KLF5抗体

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hz-3649R KLF8/KLF3  KLF样转录因子8抗体

hz-3644R KLF9/BTEB1  转录因子KLF9抗体

hz-1577R KLF13/RFLAT-1  肠道内富含的Kruppel样因子13

hz-0225R KLH  血蓝蛋白抗体

hz-0225M KLH  血蓝蛋白抗体

hz-1963R KLK1  激肽释放酶1抗体

hz-5868R KLK2  激肽释放酶2抗体

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hz-3624R Delta Opioid Receptor  D型阿片受体抗体

hz-3712R Phospho-delta Opioid Receptor (Ser363)  磷酸化D型阿片受体抗体

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