细胞粘合素抗体(C端)腱糖蛋白-C(固生蛋白)抗体

英文名称    Tenascin C    

中文名称    细胞粘合素抗体(C端)腱糖蛋白-C(固生蛋白)抗体    

别    名    150 225; Cytotactin; Glioma associated extracellular matrix antigen; Glioma-associated-extracellular matrix antigen; GMEM; GP 150 225; GP 150-225; GP; Hexabrachion; HXB; JI; MGC167029; Miotendinous antigen; Myotendinous antigen; Neuronectin; TENA_HUMAN; Tenascin; Tenascin-C; Tenascin-C isoform 14/AD1/16; TenascinC; TN; TN C; TN-C; TNC.    

细胞粘合素抗体(C端)腱糖蛋白-C(固生蛋白)抗体     

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  免疫学  神经生物学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    230kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Tenascin C    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

细胞粘合素抗体(C端)腱糖蛋白-C(固生蛋白)抗体 产品介绍    background:
This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration. [provided by RefSeq, Jul 2011]

Function:
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.

Subunit:
Homohexamer; disulfide-linked. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4.

Subcellular Location:
Secreted, extracellular space, extracellular matrix.

Similarity:
Belongs to the tenascin family. 
Contains 15 EGF-like domains. 
Contains 1 fibrinogen C-terminal domain. 
Contains 15 fibronectin type-III domains. 

Gene ID:
3371

Database links:

Entrez Gene: 3371 Human

Entrez Gene: 21923 Mouse

Entrez Gene: 116640 Rat

Omim: 187380 Human

SwissProt: P24821 Human

SwissProt: Q80YX1 Mouse

SwissProt: B2LYI9 Rat

Unigene: 143250 Human

Unigene: 454219 Mouse

Unigene: 980 Mouse

Unigene: 12723 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

细胞粘合素抗体(C端)腱糖蛋白-C(固生蛋白)抗体 

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hz-0299R Adenylate Kinase 1/AK1  腺苷酸激酶-1抗体

hz-4095R CTNNBIP1  β链接素相互作用蛋白1抗体

hz-5265R phospho-CTNNBIP1 (Ser36)  磷酸化β链接素相互作用蛋白1抗体

hz-5266R phospho-CTNNBIP1 (Thr43/Ser50)  磷酸化β链接素相互作用蛋白1抗体

hz-5026R AKR1D1  醛固酮还原酶家族1成员D1抗体

hz-5133R ALDH1B1  乙醛脱氢酶5抗体

hz-4026R ALDOB  醛缩酶2抗体

hz-2406R Aldolase A  醛缩酶A抗体

hz-3976R Aldolase C  醛缩酶C抗体

hz-5139R ALF/GTF2A1LF  通用转录因子IIA样因子抗体

hz-0097R ALK/CD246  间变型淋巴瘤激酶抗体

hz-4096R CDC27/ANAPC3  后期促进复合蛋白3抗体

hz-7501R CO4A2  胶原蛋白4a2亚基抗体

hz-7502R Rhz/GTP binding protein Rhz1  GTP结合蛋白Rhz1抗体

hz-7503R Laminin 1+2  层粘连蛋白1+2抗体

hz-7504R Laminin Beta 2/Laminin S  层粘连蛋白β2抗体

hz-7505R Plakophilin 1  桥粒斑菲素蛋白1抗体

hz-3022R phospho-ALK/CD246(Tyr1604)  磷酸化间变型淋巴瘤激酶抗体

hz-3021R phospho-ALK/CD246(Tyr1278/1282/1283)  磷酸化间变型淋巴瘤激酶抗体

hz-3047R phospho-ALK/CD246(Tyr1586)  磷酸化间变型淋巴瘤激酶抗体

hz-7506R SMOC2  分泌模块化钙结合蛋白2抗体（平滑肌相关蛋白2）

hz-7507R Sprouty 2  快速发育生长因子同源蛋白2抗体

hz-7508R THSD1  血小板跨膜反应蛋白1抗体

hz-7509R VG5Q/AGGF1  血管生长因子VG5Q抗体

hz-7510R stabilin1/STAB 1  淋巴管内皮细胞和血管内皮细胞受体1抗体

hz-7511R UTS2D  尾加压素2相关肽抗体

hz-7512R Hyp/hydroxyproline  羟脯氨酸抗体

hz-7513R BAI1  脑特异性血管生成抑制蛋白1抗体

hz-7514R BAI2/Brain Specific Angiogenesis Inhibitor 2  脑特异性血管生成抑制蛋白2抗体

hz-7515R KLHL20  Kelch样蛋白20抗体

hz-7516R LECT1  白细胞衍生化学吸引素抗体

hz-7517R Natriuretic Peptide Receptor A  利钠肽受体A抗体

hz-7518R Ribonuclease Inhibitor  核糖核酸酶抑制因子1抗体

hz-7519R ShzA4A  跨膜蛋白ShzA4A抗体