睾丸特异定蛋白质编码Y1抗体

英文名称    TSPY1    

中文名称    睾丸特异定蛋白质编码Y1抗体    

别    名    DYS14; pJA 923; pJA923; Testis specific protein Y linked 1; Testis specific Y encoded protein 1; TSPY 1; TSPY; TSPY1_HUMAN.    

 睾丸特异定蛋白质编码Y1抗体     

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  细胞生物  发育生物学  染色质和核信号  干细胞      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    34kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human TSPY1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

 睾丸特异定蛋白质编码Y1抗体产品介绍    background:
The function of this protein is unknown. TSPY genes are located on the Y-chromosome of several mammalian species. TSPY encodes a testis-specific protein 1, which probably acts as nucleosome-binding transcription factor. Homology with the SET/NAP/DENTT oncogene family suggest a role in spermatogonic cell division and seminal oncogenesis.

Function:
May be involved in sperm differentiation and proliferation.

Subcellular Location:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Also found in nucleus.

Tissue Specificity:
Specifically expressed in testicular tissues. Isoform 1 and isoform 2 are expressed in spermatogonia and spermatocytes. Found in early testicular carcinoma in situ, spermatogonial cells in testicular tissues of 46,X,Y female and in prostate cancer cell lines.

Post-translational modifications:
Phosphorylated.

Similarity:
Belongs to the nucleosome assembly protein (NAP) family.

Database links:
 

UniProtKB/Swiss-Prot: Q01534.4

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

 睾丸特异定蛋白质编码Y1抗体

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