味觉2型受体蛋白家族49抗体

英文名称    TAS2R49    

中文名称    味觉2型受体蛋白家族49抗体    

别    名    T2R20; T2R20_HUMAN; T2R49; T2R56; TAS2R20; Taste receptor type 2 member 20; Taste receptor type 2 member 49; Taste receptor type 2 member 56    

味觉2型受体蛋白家族49抗体    

说 明 书    0.2ml      

研究领域    细胞生物  神经生物学  信号转导  通道蛋白  细胞膜受体  G蛋白偶联受体  G蛋白信号  细胞膜蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    35kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human TAS2R49    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

味觉2型受体蛋白家族49抗体 产品介绍    background:
The sense of taste provides animals with valuable information about the quality and nutritional value of food. A family of G protein coupled receptors are involved in taste perception and include T1R, which is involved in sweet and umami taste perception and T2R, which is involved in bitter taste perception. Both types of taste receptors couple to various G proteins to initiate signal transduction cascades. T2R49 plays a role in sensing the chemical composition of the gastrointestinal content. T2R49 is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.

Function:
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.

Similarity:
Belongs to the G-protein coupled receptor T2R family.

Database links:
UniProtKB/Swiss-Prot: P59543.2

Important Note:
This product as supplied is in    

味觉2型受体蛋白家族49抗体 

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