等上游刺激因子1抗体

英文名称    USF-1    

中文名称    等上游刺激因子1抗体    

别    名    bHLHb11; USF1; USF 1; Class B basic helix-loop-helix protein 11; FCHL 1; FCHL; FCHL1; HGNC:12593; HYPLIP 1; HYPLIP1; Major late transcription factor 1; Major late transcription factor; MLTF; MLTF I; MLTFI; Transcription factor USF-1; UEF; Upstream stimulatory factor 1; Upstream transcription factor 1; Upstream transcription factor 1, isoform CRA_a; USF; USF1_HUMAN.    

等上游刺激因子1抗体            

说 明 书    0.1ml  0.2ml      

研究领域    心血管      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    34kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human USF-1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

等上游刺激因子1抗体    产品介绍    background:
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this gene. Alternate Names: upstream stimulatory factor 1; transcription factor USF-1; bHLHb11; Upstream stimulatory factor 1; Major late transcription factor 1.

Function:
Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.

Subunit:
Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a homodimer or a heterodimer (USF1/USF2). Interacts with varicella-zoster virus IE62 protein.

Subcellular Location:
Nucleus.

DISEASE:
Hyperlipidemia combined 1 (HYPLIP1) [MIM:602491]: A disorder characterized by a variable pattern of elevated levels of serum total cholesterol, triglycerides or both. It is observed in a percentage of individuals with premature coronary heart disease. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Similarity:
Contains 1 bHLH (basic helix-loop-helix) domain.

Gene ID:
7391

Database links:

Entrez Gene: 7391 Human

Entrez Gene: 22278 Mouse

Entrez Gene: 83586 Rat

Omim: 191523 Human

SwissProt: P22415 Human

SwissProt: Q61069 Mouse

Unigene: 414880 Human

Unigene: 8 Mouse

Unigene: 10845 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

等上游刺激因子1抗体    

hz-0293M-hzy5.5 Mouse Anti-rat IgG/Cy5.5  Cy5.5标记的小鼠抗大鼠IgG

hz-0293M-hzy7 Mouse Anti-rat IgG/Cy7  Cy7标记的小鼠抗大鼠IgG

hz-0293M-PE Mouse Anti-rat IgG/PE  PE标记的小鼠抗大鼠IgG

hz-0293M-PE-hzy3 Mouse Anti-rat IgG/PE-Cy3  PE-Cy3标记的小鼠抗大鼠IgG

hz-0293M-PE-hzY5 Mouse Anti-rat IgG/PE-CY5  PE-CY5标记的小鼠抗大鼠IgG

hz-0293M-APhz Mouse Anti-rat IgG/APC  APC标记的小鼠抗大鼠IgG

hz-0293M-AF350 Mouse Anti-rat IgG/Alexa Fluor 350  Alexa Fluor 350标记的小鼠抗大鼠IgG

hz-0293M-AF488 Mouse Anti-rat IgG/Alexa Fluor 488  Alexa Fluor 488标记的小鼠抗大鼠IgG

hz-0293M-AF555 Mouse Anti-rat IgG/Alexa Fluor 555  Alexa Fluor 555标记的小鼠抗大鼠IgG

hz-0293M-AF647 Mouse Anti-rat IgG/Alexa Fluor 647  Alexa Fluor 647标记的小鼠抗大鼠IgG

hz-0293M-PE-hzy5.5 Mouse Anti-rat IgG/PE-Cy5.5  PE-Cy5.5标记的小鼠抗大鼠IgG

hz-0293M-Gold Mouse Anti-rat IgG/Gold  胶体金标记的小鼠抗大鼠IgG

hz-0293M-AP Mouse Anti-rat IgG/AP  碱性磷酸酶（AP）标记的小鼠抗大鼠IgG

hz-0293M-FIThz Mouse Anti-rat IgG/FITC  FITC标记的小鼠抗大鼠IgG

hz-0293M-HRP Mouse Anti-rat IgG/HRP  辣根过氧化物酶标记的小鼠抗大鼠IgG

hz-0293M-RBIThz Mouse Anti-rat IgG/RBITC  罗丹明标记的小鼠抗大鼠IgG

hz-0293M-Bio Mouse Anti-rat IgG/Bio  生物素标记的小鼠抗大鼠IgG

hz-0293M-PE-hzy7 Mouse Anti-rat IgG/PE-Cy7  PE-Cy7标记的小鼠抗大鼠IgG

hz-0326M-Bio Mouse Anti-Bov IgG/Bio  生物素标记的小鼠抗牛IgG

hz-0326M-hzy3 Mouse Anti-Bov IgG/Cy3  Cy3标记的小鼠抗牛IgG

hz-0326M-AP Mouse Anti-Bov IgG/AP  碱性磷酸酶（AP）标记的小鼠抗牛IgG

hz-0326M-PE-hzy7 Mouse Anti-Bov IgG/PE-Cy7  PE-Cy7标记的小鼠抗牛IgG

hz-0326M-Gold Mouse Anti-Bov IgG/Gold  胶体金标记的小鼠抗牛IgG

hz-0326M-HRP Mouse Anti-Bov IgG/HRP  辣根过氧化物酶标记的小鼠抗牛IgG

hz-0326M-RBIThz Mouse Anti-Bov IgG/RBITC  罗丹明标记的小鼠抗牛IgG

hz-0326M-FIThz Mouse Anti-Bov IgG/FITC  FITC标记的小鼠抗牛IgG

hz-0326M-hzy5 Mouse Anti-Bov IgG/Cy5  Cy5标记的小鼠抗牛IgG

hz-0326M-hzy5.5 Mouse Anti-Bov IgG/Cy5.5  Cy5.5标记的小鼠抗牛IgG

hz-0326M-hzy7 Mouse Anti-Bov IgG/Cy7  Cy7标记的小鼠抗牛IgG

hz-0326M-PE Mouse Anti-Bov IgG/PE  PE标记的小鼠抗牛IgG

hz-0326M-PE-hzy3 Mouse Anti-Bov IgG/PE-Cy3  PE-Cy3标记的小鼠抗牛IgG

hz-0326M-PE-hzY5 Mouse Anti-Bov IgG/PE-CY5  PE-CY5标记的小鼠抗牛IgG

hz-0326M-APhz Mouse Anti-Bov IgG/APC  APC标记的小鼠抗牛IgG

hz-0326M-AF350 Mouse Anti-Bov IgG/Alexa Fluor 350  Alexa Fluor 350标记的小鼠抗牛IgG