长链脂肪酸转运蛋白1抗体

英文名称    SLC27A1    

中文名称    长链脂肪酸转运蛋白1抗体    

别    名    FATP1; ACSVL5; FATP 1; FATP; Fatty acid transport protein 1; Long chain fatty acid transport protein 1; Solute carrier family 27 (fatty acid transporter) member 1; Solute carrier family 27 member 1; S27A1_HUMAN.    

长链脂肪酸转运蛋白1抗体      

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  免疫学  染色质和核信号  信号转导  细胞骨架      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, Danio rerio    

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    71kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human SLC27A1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

长链脂肪酸转运蛋白1抗体 产品介绍    background:
SLC27A1 (Solute carrier family 27 member 1) is involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. SLC27A1 may act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. It also plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis and may be involved in regulation of cholesterol metabolism. 

Function:
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

Subunit:
Self-associates. May function as a homodimer.

Subcellular Location:
Cell membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Cytoplasm. Note=Plasma membrane and intracellular membranes, at least in adipocytes. Predominantly cytoplasmic in myocytes.

Tissue Specificity:
Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver.

Similarity:
Belongs to the calponin family. 
Contains 3 calponin-like repeats. 
Contains 1 CH (calponin-homology) domain.

Gene ID:
376497

Database links:

Entrez Gene: 376497 Human

Entrez Gene: 26457 Mouse

Omim: 600691 Human

SwissProt: Q6PCB7 Human

SwissProt: Q60714 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

长链脂肪酸转运蛋白1抗体 

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