纺锤体和着丝粒相关蛋白3抗体

英文名称    SKA3    

中文名称    纺锤体和着丝粒相关蛋白3抗体    

别    名    C13orf3; RAMA1; SKA3; SKA3_HUMAN; Spindle and kinetochore associated complex subunit 3; Spindle and kinetochore-associated protein 3.    

纺锤体和着丝粒相关蛋白3抗体        

说 明 书    0.2ml      

研究领域    细胞生物  细胞周期蛋白  细胞分化      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    46kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human SKA3    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

纺锤体和着丝粒相关蛋白3抗体 产品介绍    background:
Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization.

Function:
Component of the SKA1 complex, a microtubule-bindingsubcomplex of the outer kinetochore that is essential for properchromosome segregation. The SKA1 complex is a direct component ofthe kinetochore-microtubule interface and directly associates withmicrotubules as oligomeric assemblies. The complex facilitates theprocessive movement of microspheres along a microtubule in adepolymerization-coupled manner. In the complex, it mediates themicrotubule-stimulated oligomerization.

Subunit:
Component of the SKA1 complex, composed of SKA1, SKA2 andSKA3. The core SKA1 complex is composed of 2 SKA1-SKA2heterodimers, each heterodimer interacting with a molecule of theSKA3 homodimer. The core SKA1 complex associates with microtubulesand forms oligomeric assemblies. Interacts directly with SKA1.

Subcellular Location:
Cytoplasm, cytoskeleton, spindle.Chromosome, centromere, kinetochore. Note=Localizes to the outerkinetochore and spindle microtubules during mitosis in a NDC80complex-dependent manner. 

Similarity:
Belongs to the SKA3 family. 

Database links:
UniProtKB/Swiss-Prot: Q8IX90.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

纺锤体和着丝粒相关蛋白3抗体 

hz-7760R Factor VII light chain  凝血因子VII

hz-7761R Myosin VIIa/DFNB2  肌球蛋白7a/常染色体隐性耳聋蛋白2抗体

hz-7762R Factor X  凝血因子10抗体

hz-7763R NIR2  膜磷脂转移蛋白1抗体

hz-7764R NUSAP1  核仁和纺锤体相关蛋白1抗体

hz-7765R RAB35  RAS相关蛋白癌基因Rab35抗体

hz-7766R RACGAP1  Rho GTP酶激活蛋白GAP抗体

hz-7767R phospho-RACGAP1(Ser387)  磷酸化Rho GTP酶激活蛋白GAP抗体

hz-7768R RCC2  染色体浓缩调节蛋白2抗体

hz-7769R SEPT1  细胞分化蛋白SEP1抗体

hz-7770R SEPT10  细胞分化蛋白SEPT10抗体

hz-7771R SEPT12  细胞分化蛋白SEPT12抗体

hz-7772R SEPT14  细胞分化蛋白SEPT14抗体

hz-7773R SPECC1L  细胞质和纺锤体机化蛋白A抗体

hz-7774R Septin 3  神经元特异性蛋白3抗体

hz-7776R UCHL5IP  泛素羧基末端水解酶5互相作用蛋白1抗体

hz-7777R VPS4a  液泡分选蛋白4抗体

hz-7778R APC5  细胞分裂周期蛋白5抗体

hz-7779R BRD7  鼻咽癌相关转录调节蛋白抗体

hz-7780R BRRN1/CAPH  染色体相关蛋白H抗体

hz-7781R CDC123/C10orf7  细胞分裂周期蛋白CDC123抗体

hz-7782R CCDC16/zinc finger protein 830  锌指蛋白830抗体

hz-7783R CDC20B  细胞分裂周期蛋白20B抗体

hz-7784R ccnb1ip1  周期蛋白B1结合蛋白1抗体

hz-7785R CDC45L  细胞分裂周期调控蛋白45抗体

hz-7786R CDCA2  细胞分裂周期蛋白2抗体

hz-7787R CEP152  中心体蛋白152抗体

hz-7788R CEP76  中心体蛋白质76抗体

hz-7789R CHMP1B  染色质修饰蛋白1B抗体

hz-7790R CIRBP  冷诱导RNA结合蛋白抗体