Anti-MHC class I型抗体

Rabbit Anti-MHC class I型抗体 antibody

FROM:ABCAM

Catalog Number :RS-7335R

Quantity size : 0.1ml （dilute with pH 7.4 0.01 M PBS or antibody diluent ） Background: background:

MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.

Function:

Involved in the presentation of foreign antigens to the immune system.

Specificity :

–Anti-MHC class I is a rabbit polyclonal antibody

–specific for MHC class I of rat

– use for western blotting,elisa,immunoprecipitation and immunohistochemistry

–Protein G affinity chromatography purification, purity :>95%

– Isotype: IgG

– mol wt: 40 kDa

Application :

ELISA=1:500-1000

IHC-P=1:100-500

IHC-F=1:100-500

IF=1:150-200MHC class I型抗体，说明书

– not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user..

Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃MHC class I型抗体，说明书

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.