英文名称 Anti-GADD34
中文名称 生长抑制DNA损伤基因34抗体
生长抑制DNA损伤基因34抗体别 名 Growth arrest and DNA damage-inducible 34; Apoptosis associated protein; GADD 34; Growth arrest and DNA damage inducible 34; Growth arrest and DNA-damage-inducible 34; PPP1R15A; Protein phosphatase 1 regulatory (inhibitor) subunit 15A; Protein phosphatase 1 regulatory subunit 15A.
浓 度 1mg/1ml
规 格 0.1ml/100μg 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat
产品类型 一抗
公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体,产品货期短、生长抑制DNA损伤基因34抗体品质保证、全国免邮,并提供抗体相应实验技术指导。
研究领域 细胞生物 免疫学 信号转导 细胞凋亡 细胞周期蛋白 激酶和磷酸酶 表观遗传学
蛋白分子量 predicted molecular weight: 75(hu); 72(mo); 64(rat)kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human GADD34 (560-572aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with 生长抑制DNA损伤基因34抗体apoptosis following ionizing radiation.
Function : Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress.
Subunit : Interacts with PCNA (By similarity). Interacts with LYN and MLL. Interacts with PP1, PPP1R1A and SMARCB1. Interacts with SMAD7. Interacts with BAG1.
Subcellular Location : Endoplasmic reticulum.
Post-translational modifications : Phosphorylated on tyrosine by LYN; which impairs its antiproliferative activity.
Similarity : Belongs to the PPP1R15 family.
Database links : UniProtKB/Swiss-Prot: O75807.1
GADD34蛋白与细胞凋亡和死亡密切相关,在某种程度上决定了细胞周期的进程。
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ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
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ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
生长抑制DNA损伤基因34抗体ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2
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企业名称
上海研生生化试剂有限公司
企业信息已认证
企业类型
信用代码
310112001038197
成立日期
2011-01-12
注册资本
100
经营范围
上海研生实业有限公司
公司地址
上海市漕宝路66号20F
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