英文名称 Anti-eIF3K
中文名称 真核翻译起始因子3K抗体
真核翻译起始因子3K抗体别 名 ARG134; eIF 3 p25; eIF 3 p28; eIF-3 p25; eIF-3 p28; EIF3-p28; eIF3k; eif3k; EIF3K_HUMAN; EIF3S12; Eukaryotic translation initiation factor 3 subunit 12; Eukaryotic translation initiation factor 3 subunit K; HSPC029; M9; MSTP001; Muscle specific gene M9 protein; Muscle-specific gene M9 protein; PLAC 24; PLAC-24; PLAC24; PRO1474; PTD001; EIF3K_HUMAN.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Cow, Rabbit
产品类型 一抗
公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体,产品货期短、真核翻译起始因子3K抗体品质保证、全国免邮,并提供抗体相应实验技术指导。
研究领域 神经生物学 转录调节因子 细胞膜受体 G蛋白偶联受体 表观遗传学 G蛋白信号
蛋白分子量 predicted molecular weight: 25kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human eIF3K
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 eIF3K (Eukaryotic translation initiation factor 3 subunit K, Muscle-specific gene M9 protein) is a widely expressed translation initiation factor that belongs to the eIF3 subunit K family. Translation initiation factor 3 (eIF3) is a multisubunit 真核翻译起始因子3K抗体complex containing at least 12 subunits. eIF3 binds to the 40S ribosomal subunit, promotes the binding of methionyl-tRNAi and mRNA, and interacts with several other initiation factors to form the 40S initiation complex. eIF3K is the smallest subunit of eIF3 and it interacts with several other subunits of eIF3 and the 40S ribosomal subunit. eIF3K is conserved among high eukaryotes, including mammals, insects, and plants, and it is ubiquitously expressed in human tissues. eIF3K is distributed both in nucleus and cytoplasm and colocalizes with cyclin D3, a regulatory subunit of cyclin-dependent kinase 4 (Cdk4).
Function : Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Subunit : Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with CCND3, but not with CCND1 and CCND2.
Subcellular Location : Nucleus. Cytoplasm.
Tissue Specificity : Ubiquitous, with the highest levels of expression in brain, testis and kidney.
Similarity : Belongs to the eIF-3 subunit K family.
Database links : UniProtKB/Swiss-Prot: Q9UBQ5.1
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MMP-13 ELISA kit 大鼠基质金属蛋白酶13
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MMP11(Human matrix metalloproteinase 11) ELISA Kit 人基质金属蛋白酶11
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MMP-10(Human Matrix metalloproteinase 10) ELISA kit 人基质金属蛋白酶10
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MMP-10 ELISA kit 大鼠基质金属蛋白酶10
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MMP-1(Human Matrix metalloproteinase 1) ELISA kit 人基质金属蛋白酶1
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MMP-1 ELISA kit 大鼠基质金属蛋白酶1
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MMP-1 (Rabbit matrix metalloproteinase 1) ELISA Kit 兔基质金属蛋白酶1
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MLZE(Human melanomaderived leucine zipper extra-nuclear factor) ELISA Kit 人黑素瘤衍生亮氨酸拉链额外核因子
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MLKL(Human mixed lineage kinase domain-like) ELISA Kit 人混合系列蛋白激酶样结构域
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MLCK(Human myosin light chain kinase) ELISA Kit 人肌球蛋白轻链激酶
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MLC(Human Myosin light Chain) ELISA Kit 人肌球蛋白轻链
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MKK6(Human mitogen activated protein kinase kinase 6) ELISA Kit 人丝裂原活化蛋白激酶激酶6
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MK(Human Midkine) ELISA Kit 人中期因子
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MIS/AMH)ELISA Kit 大鼠缪勒管抑制物质/抗缪勒管激素
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MIS/AMH(Human Mullerian Inhibiting Substance/Anti-Mullerian hormone) ELISA Kit 人缪勒管抑制物质/抗缪勒管激素
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MIP-5(Human macrophage inflammatory protein 5) ELISA Kit 人巨噬细胞炎性蛋白5
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MIP-5 ELISA Kit 大鼠巨噬细胞炎症蛋白5
真核翻译起始因子3K抗体ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MIP-3 Beta/ELC/CCL19(Mouse macrophage inflammatory protein 3 Beta) ELISA Kit 小鼠巨噬细胞炎性蛋白3β
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MIP-3 Beta/ELC/CCL19(Human Macrophage Inflammatory Protein-3 Beta) ELISA kit 人巨噬细胞炎性蛋白3β
ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2 MIP-3 Beta/ELC/CCL19 ELISA Kit 大鼠巨噬细胞炎性蛋白3β
更多真核翻译起始因子3K抗体价格、 真核翻译起始因子3K抗体批发价、 真核翻译起始因子3K抗体品牌、厂家及抗体详细说明书,都可跟我们销售人员索取。