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当前位置: 上海研生 > 抗体/抗原 > 酪氨酸蛋白激酶受体B1抗体

酪氨酸蛋白激酶受体B1抗体

供货周期: 现货
品牌: GenWay
规格: 0.1ml/100μg 0.2ml/200μg
货号:
CAS号:
报价: ¥1
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产品介绍

英文名称  Anti-EphB1/Eph receptor B1 

中文名称  酪氨酸蛋白激酶受体B1抗体 

酪氨酸蛋白激酶受体B1抗体别    名  Cek 6; Elkh; Eph tyrosine kinase 2; EPH2; EphB1; Ephrin receptor Eph B1 precursor; Ephrin type B receptor 1; HEK 6; NET; Neuronally expressed EPH related tyrosine kinase; Tyrosine protein kinase receptor EPH 2. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg     

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit

产品类型  一抗    

公司全程供应AbcamCSTAbnovaBDGeneTexProteintechSBAbgentAbFrontierAnaSpecAgriseraAlomoneEpitomicsActive MotifAssaybiotechBiorbytBioVisionBenderCaymanChemicalCovanceChromoTekEnzoeBioscienceGlen ResearchMBLProSciPeproTechSwantVector等品牌公司抗体,产品货期短、酪氨酸蛋白激酶受体B1抗体品质保证、全国免邮,并提供抗体相应实验技术指导。

研究领域  心血管 细胞生物 神经生物学 信号转导 激酶和磷酸酶 细胞膜受体  

蛋白分子量  predicted molecular weight: 106kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human EphB1/Eph receptor B1 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  IF=1:100-500 

(石蜡切片需做抗原修复) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 EphB1, previously known as Elk (eph like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. EphB family proteins bind ephrins of the B class. EphB1 is expressed predominately in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, EphB1 signals regulation of cell attachment and cell to cell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.

Subunit : Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses. Interacts with EPHB6; transphosphorylates EPHB6 to form an active signaling complex. Interacts with PICK1. Interacts (through Tyr-594) with NCK1 (via SH2 domain); activates the JUN cascade to regulate cell adhesion. The 酪氨酸蛋白激酶受体B1抗体ligand-activated form interacts (through Tyr-928) with GRB7 and GRB10 (via SH2 domains). The ligand-activated form interacts (residues within the catalytic domain) with GRB2 (via SH2 domain). Interacts with GRB2, SHC1 and SRC; activates the MAPK/ERK cascade to regulate cell migration. Interacts with CBL; regulates receptor degradation through ubiquitination. Interacts with ACP1.

Subcellular Location : Membrane.

Tissue Specificity : Preferentially expressed in brain.

Similarity : Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.

Contains 1 Eph LBD (Eph ligand-binding) domain.

Contains 2 fibronectin type-III domains.

Contains 1 protein kinase domain.

Contains 1 SAM (sterile alpha motif) domain.

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ANG-2 (Rabbit Angiopoietin 2) ELISA Kit  兔血管生成素2 SDA(Human salivary duct autoantibody) ELISA Kit

更多酪氨酸蛋白激酶受体B1抗体价格、 酪氨酸蛋白激酶受体B1抗体批发价、 酪氨酸蛋白激酶受体B1抗体品牌、厂家及抗体详细说明书,都可跟我们销售人员索取。


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企业名称

上海研生生化试剂有限公司

企业信息已认证

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信用代码

310112001038197

成立日期

2011-01-12

注册资本

100

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