英文名称 Anti-EZH1
中文名称 组蛋白赖氨酸N-甲基EZH1抗体
组蛋白赖氨酸N-甲基EZH1抗体别 名 Enhancer of zeste homolog 1(Drosophila); Enhancer of zeste homolog 1; ENX-2; ENX2; EZH1; EZH1: enhancer of zeste homolog 1 (Drosophila); EZH1_HUMAN; Histone-lysine N-methyltransferase EZH1; KIAA0388.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Guinea Pig
产品类型 一抗
公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体,产品货期短、组蛋白赖氨酸N-甲基EZH1抗体品质保证、全国免邮,并提供抗体相应实验技术指导。
研究领域 肿瘤 染色质和核信号 肿瘤细胞生物标志物 表观遗传学
蛋白分子量 predicted molecular weight: 95kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human EZH1 (471-510aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
组蛋白赖氨酸N-甲基EZH1抗体产品介绍 Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Sequence similarities
Belongs to the histone-lysine methyltransferase family. EZ subfamily. Contains 1 SET domain.
Function : Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Subunit : Component of the PRC2/EED-EZH1 complex, which includes EED, EZH1, SUZ12, RBBP4 and AEBP2. The PRC2/EED-EZH1 is less abundant than the PRC2/EED-EZH2 complex, has weak methyltransferase activity and compacts chromatin in the absence of the methyltransferase cofactor S-adenosyl-L-methionine (SAM).
Subcellular Location : Nucleus. Note=Colocalizes with trimethylated 'Lys-27' of histone H3.
Similarity : Belongs to the histone-lysine methyltransferase family. EZ subfamily.
Contains 1 CXC domain.
Contains 1 SET domain.
Human estrogen ELISA Kit 人雌激素(estrogen)
Human Estradiol ELISA Kit 人雌二醇(E2)
Human SOD ELISA Kit 人超氧化物歧化酶(SOD)ELISA试剂盒
Human High sensitivity C-reactive protein ELISA Kit 人超敏C反应蛋白(hs-CRP)ELISA Kit
Human iFABP ELISA Kit 人肠脂肪酸结合蛋白(iFABP)ELISA试剂盒
Laminin 人层粘连蛋白
Human Laminin ELISA KIT 人层连蛋白(Laminin)
Human ADMA ELISA Kit 人不对称二甲基精氨酸(ADMA)
Human C5a ELISA Kit 人补体片断C5a(C5a)
Human C4a ELISA Kit 人补体片断C4a(C4a)
Human C3a ELISA Kit 人补体片断C3a(C3a)
Human C1q ELISA Kit 人补体1q(C1q)
Human Pyruvate Kinase M2 ELISA Kit 人丙酮酸激酶M2型同工酶(M2-PK)
Human malondialchehyche ELISA Kit 人丙二醛(MDA)ELISA试剂盒
Human Epidermal Growth Factor Receptor ELISA kit 人表皮细胞生长因子受体(EGFR)
Human Epidermal growth factor ELISA Kit 人表皮细胞生长因子(EGF)
Human EGF ELISA Kit 人表皮生长因子(EGF)
Human PyriLinks ELISA Kit 人吡啶吩(PyriLinks)
Human LIFR ELISA Kit 人白血病抑制因子受体(LIFR)
Human Leukemia inhibitory factor, LIF ELISA kit 人白血病抑制因子(LIF)
Human leucocyte antigen-B27 ELISA Kit 人白细胞抗原B27(HLA-B27)
Human ALCAM Elisa Kit 人白细胞活化黏附因子(ALCAM)
Human LTC4 ELISA Kit 人白三烯C4(LTC4)
Human LTB4 ELISA Kit 人白三烯B4(LTB4)ELISA试剂盒
Human Interleukin-9,IL-9 ELISA KIT 人白介素-9(IL-9)
Human Interleukin-8,IL-8 ELISA KIT 人白介素-8(IL-8)ELISA KIT
Human Interleukin-6 ELISA KIT 人白介素6(IL-6) ELISA KIT
Human Interleukin-4,IL-4 ELISA KIT 人白介素4(IL-4)
Human Interleukin-3,IL-3 ELISA KIT 人白介素3(IL-3)
组蛋白赖氨酸N-甲基EZH1抗体Human Interleukin-2 soluble receptor alpha chain,IL-2sRβ ELISA kit 人白介素2可溶性受体β链(IL-2sRβ )
Human Interleukin-2 soluble receptor alpha chain,IL-2sRα ELISA kit 人白介素2可溶性受体α链(CD25) (IL-2sRα )
human Interleukin27 ELISA Kit 人白介素27(IL-27)
Human Interleukin23 ELISA Kit 人白介素23(IL-23)
更多组蛋白赖氨酸N-甲基EZH1抗体价格、 组蛋白赖氨酸N-甲基EZH1抗体批发价、 组蛋白赖氨酸N-甲基EZH1抗体品牌、厂家及抗体详细说明书,都可跟我们销售人员索取。
更多
企业名称
上海研生生化试剂有限公司
企业信息已认证
企业类型
信用代码
310112001038197
成立日期
2011-01-12
注册资本
100
经营范围
上海研生实业有限公司
公司地址
上海市漕宝路66号20F
客服电话