抑癌蛋白DKK3抗体

供货周期： 7天

品牌： Abcam

型号： 0.2ml/200μg

货号：

报价： ¥1

留言咨询

产品介绍

抑癌蛋白DKK3抗体英文名称 Anti-DKK3

中文名称抑癌蛋白DKK3抗体

别名 Dickkopf 3; Dickkopf homolog 3; Dickkopf related protein 3; Dickkopf related protein 3 Precursor; Dickkopf3; DKK 3; DKK3; hDkk 3; hDkk3; REIC; RIG-like 5-6; RIG-like 7-1.

公司抑癌蛋白DKK3抗体应用于医学免疫学、动物免疫学、分子生物学、生物化学、临床医学、检验医学、动物医学、药学、理工、农学、环境学等生命科学密切相关的专业。

浓度 1mg/1ml

规格 0.1ml/100μg 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit

产品类型一抗

研究领域肿瘤细胞生物免疫学信号转导转录调节因子

蛋白分子量 predicted molecular weight: 36kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human DKK3

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

抑癌蛋白DKK3抗体产品介绍 Dickkopf 3, like DKK1, DKK2, and DKK4, possesses an N terminal signal peptide and 2 conserved cysteine rich domains, which are separated by a linker region and contain 10 cysteine residues each. The second cysteine region has a putative lipid binding function that may facilitate WNT/DKK interactions at the plasma membrane. The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids. All DKKs have several potential sites for cleavage by furin type proteases.

Subunit : Interacts with LRP5 and LRP6.

Subcellular Location : Secreted.

Tissue Specificity : Highest expression in heart, brain, and spinal cord.

Similarity : Belongs to the dickkopf family.

【存储要求】连续使用时4°C存储，保质期六个月；抑癌蛋白DKK3抗体期存储时建议分装为10ul以上小包装-20°C存储，并避免反复冻融，保质期一年。

实验的用途：

1）WB：Western Blotting 免疫印迹

2）IH：Immunohistochemistry 免疫组化

3）IH(P)：Immunohistochemistry Parraffin sections 免疫组化(石蜡)

4）IH(F)：Immunohistochemistry Frozen sections 免疫组化(冰冻)

5）IC：Immunocytochemistry 免疫细胞化学