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丝氨酸/苏氨酸蛋白激酶17A/DAP凋亡诱导蛋白激酶1抗体

供货周期：一周

品牌： Abcam

规格： 0.2ml/200μg

货号：

CAS号：

报价： ¥1

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产品介绍

丝氨酸/苏氨酸蛋白激酶17A/DAP凋亡诱导蛋白激酶1抗体英文名称 Anti-DRAK1/STK17A

中文名称丝氨酸/苏氨酸蛋白激酶17A/DAP凋亡诱导蛋白激酶1抗体

别名 DAP kinase-related apoptosis-inducing protein kinase 1; death-associated protein kinase-related 1; EC 2.7.11.1; Serine / threonine kinase 17a death associated protein kinase related 1; Serine/threonine kinase 17a; Serine/threonine protein kinase 17a; STK17 A; STK17A; ST17A_HUMAN.

公司丝氨酸/苏氨酸蛋白激酶17A/DAP凋亡诱导蛋白激酶1抗体应用于医学免疫学、动物免疫学、分子生物学、生物化学、临床医学、检验医学、动物医学、药学、理工、农学、环境学等生命科学密切相关的专业。

浓度 1mg/1ml

规格 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat

产品类型一抗

研究领域细胞生物信号转导细胞凋亡激酶和磷酸酶

蛋白分子量 predicted molecular weight: 50kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human DRAK1/STK17A

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

丝氨酸/苏氨酸蛋白激酶17A/DAP凋亡诱导蛋白激酶1抗体产品介绍 DRAK1 (DAP kinase-related apoptosis-inducing protein kinase 1) is a novel member of the ser/thr protein kinase family, which mediate apoptosis through their catalytic activities. The full-length cDNA encodes a deduced 414-amino acid protein with a molecular mass of 46.56 kD. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. DRAK1 messenger RNA appears to be ubiquitously expressed in human tissues. Overexpression of DRAK1 induces apoptosis. It has been shown in vitro that DRAK1 is capable of autophosphorylation and of phosphorylating the myosin light chain as an exogenous substrate, and that the noncatalytic C terminus is crucial for full kinase activity.

Function : Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species.

Subcellular Location : Nucleus.

Tissue Specificity : Highly expressed in placenta. Lower levels in heart, lung, skeletal muscle, kidney and pancreas.

Post-translational modifications : Autophosphorylated.

Similarity : Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.

Contains 1 protein kinase domain.

Database links : UniProtKB/Swiss-Prot: Q9UEE5.2

【存储要求】连续使用时4°C存储，保质期六个月；丝氨酸/苏氨酸蛋白激酶17A/DAP凋亡诱导蛋白激酶1抗体期存储时建议分装为10ul以上小包装-20°C存储，并避免反复冻融，保质期一年。

实验的用途：

1）WB：Western Blotting 免疫印迹

2）IH：Immunohistochemistry 免疫组化

3）IH(P)：Immunohistochemistry Parraffin sections 免疫组化(石蜡)

4）IH(F)：Immunohistochemistry Frozen sections 免疫组化(冰冻)

5）IC：Immunocytochemistry 免疫细胞化学