21号染色体开放阅读框106抗体

21号染色体开放阅读框106抗体英文名称  Anti-DIP2A/C21orf106 

中文名称  21号染色体开放阅读框106抗体 

别    名  C21orf106; DIP 2A; DIP2; DIP2 disco interacting protein 2 homolog A; DIP2 homolog A; DIP2 like protein; Disco interacting protein 2 homolog; KIAA0184; DIP2A_HUMAN. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg          

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Chicken, Cow, Sheep   

产品类型  一抗    

研究领域  细胞生物 细胞周期蛋白 转录调节因子 细胞分化 表观遗传学  

蛋白分子量  predicted molecular weight: 170kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human DIP2A/C21orf106 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

21号染色体开放阅读框106抗体产品介绍 DIP2A, also known as DIP2, is a 1571 amino acid nuclear protein. It is one of three human homologs (DIP2A, DIP2B and DIP2C) of the Drosophila dip2 (disconnected-interacting protein 2) protein. In Drosophila, dip2 interacts with disco, a protein required for neuronal connections in the visual systems of larvae and adults. The closest vertebrate homologs to disco are the basonuclin genes. In mice, DIP2 homologs show restricted expression to the brain. This suggests that, similar to the function of Drosophila dip2, vertebrate DIP2 homologs may play a role in the development of the nervous system. Expressed ubiquitously with highest expression in the brain, DIP2A is thought to function in signaling throughout the central nervous system by providing positional clues for axon patterning and pathfinding. Four isoforms of DIP2A exist due to alternative splicing events.

Function : May provide positional cues for axon pathfinding and patterning in the central nervous system. 

Subcellular Location : Nuclear

Tissue Specificity : Low expression in all tissues tested. 

Similarity : Belongs to the DIP2 family.

Database links : UniProtKB/Swiss-Prot: Q14689.2