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ProSpec（蛋白质专家）是以色列一家具有超过16年历史的，专业从事细菌来源重组蛋白生产的先进生物技术公司。ProSpec生产多种细胞因子、生长因子、趋化因子、激素、酶、病毒抗原和许多其他重组蛋白。在研究团队和科学家们的努力下，ProSpec已经拥有超过1700种可用于癌症、细胞凋亡、发育、内分泌学、免疫学、神经科学、蛋白酶及干细胞研究用重组蛋白、多肽和抗体。10多年蛋白纯化方面的经验使ProSpec公司生产成本低、产量高、效率高，其蛋白产品不仅纯度高、生物活性高，价格也非常具有优势。同时ProSpec针对客户的需要提供自定义重组蛋白生产服务。
ProSpec向客户提供蛋白质产品、服务和技术授权。因为创新的产品、卓越的客户服务和对细节的注重，ProSpec在科学界建立了良好的信誉，具有广泛的客户群，包括世界各地的学术、政府研究机构，生物技术和制药企业以及医院和基准实验室。
热门产品
Adiponectin 脂连蛋白；
BDNF 神经营养因子
bFGF碱性成纤维生长因子
BMP-7 骨形态发生蛋白-7
EGF上表皮生长因子
follistatin卵泡休止素
GMCSF粒—巨噬细胞集落刺激因子
IGF1胰岛素样生长因子1
Leptin 瘦素
PDGF-BB血小板源性生长因子-BB
Myostatin 肌肉生长抑制素
Prolactin 催乳素
RANKL细胞核因子κB受体活化因子配基
SCF 干细胞因子
TGF Beta3转化生长因子-β3
TNF Alpha 肿瘤坏死因子α
VEGF 血管内皮生长因子
白介素系列
产品详情：
重组人生长分化因子15|Human GDF15
Recombinant Human Growth and Differentiation factor 15
| Catalogue Number | CYT-335 |
| Synonyms | GDF-15, MIC1, MIC-1, NAG-1, PDF, PLAB, PTGFB, Growth/differentiation factor 15, Placental bone morphogenetic protein, Placental TGF-beta, Macrophage inhibitory cytokine 1, Prostate differentiation factor, NSAID-activated gene 1 protein, NSAID-regulated gene 1 protein, NRG-1, GDF15. |
| Introduction | GDF15 is part of the TGF-Beta superfamily that is involved in regulating inflammatory and apoptotic pathways in injured tissues and throughout disease processes. GDF15 is most abundant in the liver. Its expression in liver can be considerably up-regulated in during injury of organs such as liver, kidney, heart and lung. GDF-15 promotes proliferation or growth arrest and differentiation due to differences in cellular differentiation. GDF15 prevents apoptosis in cerebellar granule neurons by activating Akt and inhibiting endogenously active ERK. GDF15 is a novel autocrine/endocrine factor that antagonizes the hypertrophic response and loss of ventricular performance. |
| Description | GDF15 Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated, Polypeptide chain containing 2x113 amino acids and having a molecular mass of 24.5 kDa. The GDF15 is purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearence | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Fomrulation | GDF15 is lyophilized without additives. |
| Solubility | It is recommended to reconstitute the lyophilized GDF15 in sterile 5mM AcOH (acetic Acid) at a concentration of 100μg/ml, which can then be further diluted to other aqueous solutions. |
| Stability | Lyophilized GDF15 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GDF15 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Purity | Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
| Biological Activity | The biological activity was assessed by the inhibition of DU-145 cells and was found to be 1-2μg/ml. |
| Amino Acid Sequence | MARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLI QKTDTGVSLQ TYDDLLAKDC HCI. |
| Usage | ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
| Related Products | ? 重组人生长分化因子15D/GDF15 D Human ? 重组人生长分化因子15/GDF15 Human, His |
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企业名称
上海高创化学科技有限公司
企业信息已认证
企业类型
信用代码
310228001353263
成立日期
2010-06-05
注册资本
10
经营范围
从事化学科技、计算机领域内技术开发、技术咨询、技术服务,从事生物科技领域内技术开发、技术咨询,化学试剂、化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备(除医疗器械),仪器仪表,Ⅰ类医疗器械,金属制品,电子产品,机电产品销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海高创化学科技有限公司
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上海市涞亭南路888弄238号
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公司名称： 上海高创化学科技有限公司
公司地址： 上海市涞亭南路888弄238号 联系人： 范先生 邮编： 201615
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