ProSpec(蛋白质专家)是以色列一家具有超过16年历史的,专业从事细菌来源重组蛋白生产的先进生物技术公司。ProSpec生产多种细胞因子、生长因子、趋化因子、激素、酶、病毒抗原和许多其他重组蛋白。在研究团队和科学家们的努力下,ProSpec已经拥有超过1700种可用于癌症、细胞凋亡、发育、内分泌学、免疫学、神经科学、蛋白酶及干细胞研究用重组蛋白、多肽和抗体。10多年蛋白纯化方面的经验使ProSpec公司生产成本低、产量高、效率高,其蛋白产品不仅纯度高、生物活性高,价格也非常具有优势。同时ProSpec针对客户的需要提供自定义重组蛋白生产服务。
ProSpec向客户提供蛋白质产品、服务和技术授权。因为创新的产品、卓越的客户服务和对细节的注重,ProSpec在科学界建立了良好的信誉,具有广泛的客户群,包括世界各地的学术、政府研究机构,生物技术和制药企业以及医院和基准实验室。
热门产品
Adiponectin 脂连蛋白;
BDNF 神经营养因子
bFGF碱性成纤维生长因子
BMP-7 骨形态发生蛋白-7
EGF上表皮生长因子
follistatin卵泡休止素
GMCSF粒—巨噬细胞集落刺激因子
IGF1胰岛素样生长因子1
Leptin 瘦素
PDGF-BB血小板源性生长因子-BB
Myostatin 肌肉生长抑制素
Prolactin 催乳素
RANKL细胞核因子κB受体活化因子配基
SCF 干细胞因子
TGF Beta3转化生长因子-β3
TNF Alpha 肿瘤坏死因子α
VEGF 血管内皮生长因子
白介素系列
产品详情:
重组人生长分化因子15|Human GDF15 His
Recombinant Human Growth and Differentiation factor 15 His Tag
Catalogue Number | CYT-691 |
Synonyms | GDF-15, MIC1, MIC-1, NAG-1, PDF, PLAB, PTGFB, Growth/differentiation factor 15, Placental bone morphogenetic protein, Placental TGF-beta, Macrophage inhibitory cytokine 1, Prostate differentiation factor, NSAID-activated gene 1 protein, NSAID-regulated gene 1 protein, NRG-1, GDF15. |
Introduction | GDF15 is part of the TGF-Beta superfamily that is involved in regulating inflammatory and apoptotic pathways in injured tissues and throughout disease processes. GDF15 is most abundant in the liver. Its expression in liver can be considerably up-regulated in during injury of organs such as liver, kidney, heart and lung. GDF-15 promotes proliferation or growth arrest and differentiation due to differences in cellular differentiation. GDF15 prevents apoptosis in cerebellar granule neurons by activating Akt and inhibiting endogenously active ERK. GDF15 is a novel autocrine/endocrine factor that antagonizes the hypertrophic response and loss of ventricular performance. |
Description | Recombinant Human GDF15 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 151 amino acids (195-308) and having a molecular mass of 16.7 kDa(molecular weight on SDS-PAGE will appear higher). GDF15 is expressed with a 36 amino acid His tag fused at N-Terminus and purified by proprietary chromatographic techniques. |
Source | Escherichia Coli. |
Physical Appearance | Sterile filtered colorless solution. |
Formulation | The GDF15 protein solution contains 10mM sodium citrate, pH-3.5 & 10% glycerol. |
Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
Purity | Greater than 95.0% as determined by SDS-PAGE. |
Amino Acid Sequence | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMARA RNGDHCPLGP GRCCRLHTVR ASLEDLGWAD WVLSPREVQV TMCIGACPSQ FRAANMHAQI KTSLHRLKPD TVPAPCCVPA SYNPMVLIQK TDTGVSLQTY DDLLAKDCHC I. |
Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
Related Products | ? 重组人生长分化因子10/GDF10 Human ? 重组人生长分化因子15D/GDF15 D Human ? 重组人生长分化因子15/GDF15 Human ? 重组人生长分化因子3/GDF3 Human ? 重组人生长分化因子5/GDF5 Human ? 重组人生长分化因子5/GDF5 Human, His |
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企业名称
上海高创化学科技有限公司
企业信息已认证
企业类型
信用代码
310228001353263
成立日期
2010-06-05
注册资本
10
经营范围
从事化学科技、计算机领域内技术开发、技术咨询、技术服务,从事生物科技领域内技术开发、技术咨询,化学试剂、化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备(除医疗器械),仪器仪表,Ⅰ类医疗器械,金属制品,电子产品,机电产品销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海高创化学科技有限公司
公司地址
上海市涞亭南路888弄238号
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