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当前位置: 上海高创 > 蛋白质/多肽 > 重组人分泌型磷脂酶A2-VII|Human PLA2G7

重组人分泌型磷脂酶A2-VII|Human PLA2G7

供货周期: 一周
品牌: Prospec-Tany
规格: 10UG
货号: enz-436
CAS号:
报价: ¥1820
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产品介绍
Synonyms Platelet-activating factor acetylhydrolase, PAF acetylhydrolase, PAF 2-acylhydrolase, LDL-associated phospholipase A2, LDL-PLA(2), 2-acetyl-1-alkylglycerophosphocholine esterase, 1-alkyl-2-acetylglycerophosphocholine esterase, PLA2G7, PAFAH, LP-PLA2, LDL-PLA2.
Introduction PLA2G7 is a secreted enzyme which catalyzes the degradation of platelet-activating factor to biologically inactive products. The PLA2G7 enzyme is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. In the blood, PLA2G7 goes mainly with LDL and less than 20% is coupled with HDL.
PLA2G7 is implicated in the development of atherosclerosis and is also a marker for cardiac disease. PLA2G7 might have a major physiologic effect in the presence of inflammatory bodily responses.
PLA2G7 alters the action of PAF (platelet-activating factor) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. PLA2G7 has specificity for substrates with a short residue at the sn-2 position. PLA2G7 is inactive against long-chain phospholipids.
PLA2G7 gene defects are the source of platelet-activating factor acetylhydrolase deficiency, which is a trait that is present in 27% of the Japanese population.
Description PLA2G7 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 420 amino acids fragment (22-441) having a total molecular mass of 52.29kDa and fused with a 4.5kDa amino-terminal hexahistidine tag.
The PLA2G7 is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered clear solution.
Formulation PLA2G7 protein is supplied in 20mM Tris-HCl pH-8.0, 1mM EDTA and 50% glycerol.
Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.
Purity Greater than 95.0% as determined by SDS-PAGE.
Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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上海高创化学科技有限公司

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信用代码

310228001353263

成立日期

2010-06-05

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10

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重组人分泌型磷脂酶A2-VII|Human PLA2G7由上海高创化学科技有限公司为您提供,货号enz-436,规格:10UG,CAS号:,如您想了解更多关于重组人分泌型磷脂酶A2-VII|Human PLA2G7价格、重组人分泌型磷脂酶A2-VII|Human PLA2G7结构式、批发、用途等信息,欢迎咨询。除供应重组人分泌型磷脂酶A2-VII|Human PLA2G7外,还可为您提供重组人HRAS样抑制3(PLA2G16)(Human HRASLS3)、重组人分泌磷脂酶A2-X(Human PLA2G10)、重组人分泌磷脂酶A2-XII(Human PLA2G12)等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海高创客户服务电话,售前、售后均可联系。
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