Solubility:DMSO 47 mg/mL, Water <1 mg/mL, Ethanol 47 mg/mL
Purity:>99%
Storage:2 years at -20 degrees centigrade
CAS No.:13010-47-4
Synonyms:CeeNU
Chemical NameN/A
Biological Activity
Description
By damaging the DNA, lomustine inhibits cancer cells and stops cells from dividing. Lomustine inhibits the growth of ZR-75-1 and U373 with IC50 of 12 uM and 15 uM, respectively. Lomustine reduces the level of expression of the DNA repair protein O6-alkylguanine-DNA alkyltransferase.