Loratadine|10mg|K1378-上海高创化学科技有限公司

SKU:K1378		M. Wt:382.88
Formula:C22H23ClN2O2		Solubility:No
Purity:>99%		Storage:2 years at -20 degrees centigrade
CAS No.:79794-75-5		Synonyms:Alavert, Claritin
Chemical NameN/A

Description	Loratadine
Targets	N/A
IC50	N/A
In vitro	Loratadine(SCH 29851) is discovered as part of a search for a new antihistamine without effects on the central nervous system (CHS). SCH 29851 has antihistamine activity in the tests used with a potency at least comparable to most standards.[1]
In vivo	Loratadine exhibits a more pronounced inhibition of histamine wheal formation than placebo or chlorpheniramine maleate (p less than 0.003). Loratadine inhibited the response for the entire observation period between 1 and 24 h post-dose. [2]SCH 29851 at 80 mg/kg po in mice, a dose about 50 times its ED50 for blocking histamine-induced paw edema in the same species, potentiated the anticonvulsant effects of diazepam. At the high dose of 320 mg/kg po, about 80 times its ED50 for antihistamine effects, SCH 29851 potentiated the ability of high doses of ethanol and hexobarbital to induce loss of righting reflexes (LRR).[3]
Clinical Trials	N/A
Features	N/A

Description

Loratadine

Targets

N/A

IC50

N/A

In vitro

Loratadine(SCH 29851) is discovered as part of a search for a new antihistamine without effects on the central nervous system (CHS). SCH 29851 has antihistamine activity in the tests used with a potency at least comparable to most standards.[1]

In vivo

Loratadine exhibits a more pronounced inhibition of histamine wheal formation than placebo or chlorpheniramine maleate (p less than 0.003). Loratadine inhibited the response for the entire observation period between 1 and 24 h post-dose. [2]SCH 29851 at 80 mg/kg po in mice, a dose about 50 times its ED50 for blocking histamine-induced paw edema in the same species, potentiated the anticonvulsant effects of diazepam. At the high dose of 320 mg/kg po, about 80 times its ED50 for antihistamine effects, SCH 29851 potentiated the ability of high doses of ethanol and hexobarbital to induce loss of righting reflexes (LRR).[3]

Clinical Trials

N/A

Features

N/A

工商信息

企业名称

上海高创化学科技有限公司

企业信息已认证

企业类型

信用代码

310228001353263

成立日期

2010-06-05

注册资本

经营范围

从事化学科技、计算机领域内技术开发、技术咨询、技术服务,从事生物科技领域内技术开发、技术咨询,化学试剂、化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备(除医疗器械),仪器仪表,Ⅰ类医疗器械,金属制品,电子产品,机电产品销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

Loratadine由上海高创化学科技有限公司为您提供，货号K1378，规格：10mg，CAS号：79794-75-5，如您想了解更多关于Loratadine价格、Loratadine结构式、批发、用途等信息，欢迎咨询。除供应Loratadine外，还可为您提供国产特级胎牛血清（无噬菌体低内毒素）、重组大鼠抵抗素(Rat Resistin)、重组人半乳糖凝集素3/Human LGALS3 His等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海高创客户服务电话，售前、售后均可联系。