TAK-700 (Orteronel)|2mg|K1377-上海高创化学科技有限公司

SKU:K1377		M. Wt:307.35
Formula:C18H17N3O2		Solubility:No
Purity:>99%		Storage:2 years at -20 degrees centigrade
CAS No.:566939-85-3		Synonyms:N/A
Chemical NameN/A

Description	TAK-700 (Orteronel)
Targets	CYP17
IC50	28 nM
In vitro	TAK-700 is a non-steroidal imidazole inhibitor and TAK-700 can inhibit CYP17 with IC50 of 28 nM. TAK-700 is a selective inhibitor for CYP17 over 11beta-hydroxylase by an impressive 260-fold.[1] TAK-700 can reduce testosterone and DHEA levels.
In vivo	TAK-700 exhibits suppressive effects on testosterone biosynthesis in rats and reduction in the weight of prostate and seminal vesicles in the rat. TAK-700 is also capable of reducing serum testosterone levels down to castration level after 8 hours following a single oral administration of 1 mg/kg to monkeys.[1]
Clinical Trials	N/A
Features	N/A

Description

TAK-700 (Orteronel)

Targets

CYP17

IC50

28 nM

In vitro

TAK-700 is a non-steroidal imidazole inhibitor and TAK-700 can inhibit CYP17 with IC50 of 28 nM. TAK-700 is a selective inhibitor for CYP17 over 11beta-hydroxylase by an impressive 260-fold.[1] TAK-700 can reduce testosterone and DHEA levels.

In vivo

TAK-700 exhibits suppressive effects on testosterone biosynthesis in rats and reduction in the weight of prostate and seminal vesicles in the rat. TAK-700 is also capable of reducing serum testosterone levels down to castration level after 8 hours following a single oral administration of 1 mg/kg to monkeys.[1]

Clinical Trials

N/A

Features

N/A

工商信息

企业名称

上海高创化学科技有限公司

企业信息已认证

企业类型

信用代码

310228001353263

成立日期

2010-06-05

注册资本

经营范围

从事化学科技、计算机领域内技术开发、技术咨询、技术服务,从事生物科技领域内技术开发、技术咨询,化学试剂、化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备(除医疗器械),仪器仪表,Ⅰ类医疗器械,金属制品,电子产品,机电产品销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

TAK-700 (Orteronel)由上海高创化学科技有限公司为您提供，货号K1377，规格：2mg，CAS号：566939-85-3，如您想了解更多关于TAK-700 (Orteronel)价格、TAK-700 (Orteronel)结构式、批发、用途等信息，欢迎咨询。除供应TAK-700 (Orteronel)外，还可为您提供重组人半乳糖凝集素8/Human LGALS8 His、优级胎牛血清（无支原体）、重组人半乳糖凝集素16/LGALS16 Human等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海高创客户服务电话，售前、售后均可联系。