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产品介绍
重组人4-羟基丙酮酸加双氧酶/HPD Human
产品编号：ENZ-015
产品规格：2ug/10ug/1mg
产品规格：2ug/10ug/1mg
| Catalogue Number | ENZ-015 |
| Synonyms | 4HPPD, GLOD3, 4-HPPD, PPD, HPPDase, Glyoxalase Domain Containing 3, 4-HydroxyphenylpYruvate Dioxygenase. |
| Introduction | 4-Hydroxyphenylpyruvate Dioxygenase Isoform-1 is an Fe-containing enzyme, which catalyzes the second reaction in the catabolism of tyrosine the conversion of 4-hydroxyphenylpyruvate to homogentisate. Present as a homodimer, HPD uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. Flaws in the gene encoding HPD result in tyrosinemia type 3 and hawkinsinuria, two inborn defects of metabolism which are related to a number of symptoms, like mental retardation and seizures and hair and urine abnormalities. |
| Description |
HPD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 413 amino acids (1-393a.a.) and having a molecular mass of 47kDa. HPD is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered clear solution. |
| Formulation | The HPD protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH 8.0) 1mM DTT, 50mM NaCl and 20% glycerol. |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MTTYSDKGAK PERGRFLHFH SVTFWVGNAK QAASFYCSKM GFEPLAYRGL ETGSREVVSH VIKQGKIVFV LSSALNPWNK EMGDHLVKHG DGVKDIAFEV EDCDYIVQKA RERGAKIMRE PWVEQDKFGK VKFAVLQTYG DTTHTLVEKM NYIGQFLPGY EAPAFMDPLL PKLPKCSLEM IDHIVGNQPD QEMVSASEWY LKNLQFHRFW SVDDTQVHTE YSSLRSIVVA NYEESIKMPI NEPAPGKKKS QIQEYVDYNG GAGVQHIALK TEDIITAIRH LRERGLEFLS VPSTYYKQLR EKLKTAKIKV KENIDALEEL KILVDYDEKG YLLQIFTKPV QDRPTLFLEV IQRHNHQGFG AGNFNSLFKA FEEEQNLRGN LTNMETNGVV PGM |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage |
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
| Usage | ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
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厦门慧嘉生物科技有限公司
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成立日期
2009-06-05
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100000
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重组人4-羟基丙酮酸加双氧酶/HPD Human由厦门慧嘉生物科技有限公司为您提供，货号ENZ-015，规格：2ug/10ug/1mg，CAS号：，如您想了解更多关于重组人4-羟基丙酮酸加双氧酶/HPD Human价格、重组人4-羟基丙酮酸加双氧酶/HPD Human结构式、批发、用途等信息，欢迎咨询。除供应重组人4-羟基丙酮酸加双氧酶/HPD Human外，还可为您提供人糖原合成酶激酶(GSK)ELISA试剂盒Human GSK ELISA试剂盒、人羧化不全骨钙素(ucOC)ELISA试剂盒Human ucOC ELISA试剂盒、人胃泌素(Gastrin)ELISA试剂盒Human Gastrin ELISA Kit等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，厦门慧嘉科技客户服务电话，售前、售后均可联系。
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