重组人肌酸激酶同工酶2(Human CKMB Type-2)

CKMBITII Human
Creatine Kinase MB Isoenzyme Type-II Human Recombinant
Catalog No. CKI-270

Synonyms:
Creatine Kinase MB Isoenzyme Type-II, CKMBITII, CKMBI, CKMB.

Introduction:
CK-MB Type II possesses the naturally occurring carboxy-terminal amino acid lysine.
This occurs during a myocardial infarct (MI or heart attack) when CK-MB Type II is released from damaged heart muscle, and the C-terminal lysine is cleaved in the blood stream, thus creating CK-MB Type I. This difference can be exploited in diagnosis of an MI.

Description:
CKMBITII Human Recombinant produced in Pichia Pastoris is a glycosylated polypeptide chain having an identical amino acid sequence compared to the native enzyme, purified under non-denaturing conditions and reacts with polyclonal antibodies to MB Isoenzyme in ELISA.
The CKMBITII is purified by proprietary chromatographic techniques.

Source:
Pichia Pastoris

Physical Appearance:
Sterile Filtered colourless liquid formulation.

Formulation:
Each mg of protein contains 20mM Tris-HCl, pH-6.8, 1mM EDTA and 1mM DTT.

Stability:
CKMBITII although stable at 15°C for 7 days, should be stored desiccated below -18°C.
Please prevent freeze-thaw cycles.

Purity:
Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Biological Activity:
The biological activity measured by the enzymatic activity of Creatine phosphokinase procedure No.45-UV, 1IU-1 µmole creatine phosphate was 892 IU/mg at 37 degrees celsius.

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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» CKBBI Human
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