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当前位置: 上海希美化学 > 蛋白质/多肽 > Recombinant Human Epithelial Neutrophil-Activating Protein 78(CXCL5)

Recombinant Human Epithelial Neutrophil-Activating Protein 78(CXCL5)

供货周期: 一周
品牌: Prospect Biosystems
规格: 5µg
货号: CHM-331
CAS号:
报价: 面议
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产品介绍

ENA 78 Human
Epithelial Neutrophil-Activating Protein 78 Human Recombinant (CXCL5)
Catalog No. CHM-331

Synonyms:
Small inducible cytokine B5, CXCL5, Epithelial-derived neutrophil-activating protein 78, Neutrophil-activating peptide ENA-78, ENA-78(1-78), chemokine (C-X-C motif) ligand 5, SCYB5.

Introduction:
Chemokine (C-X-C motif) ligand 5 (CXCL5) is a small cytokine belonging to the CXC chemokine family that is also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). It is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. Expression of CXCL5 has also been observed in eosinophils, and can be inhibited with the type II interferon IFN-γ. This chemokine stimulates the chemotaxis of neutrophils possesses angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2. The gene for CXCL5 is encoded on four exons and is located on human chromosome 4 amongst several other CXC chemokine genes. CXCL5 has been implicated in connective tissue remodelling.

Description:
Epithelial Neutrophil-Activating Protein 78 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 74 amino acids and having a molecular mass of 8020 Dalton.
The CXCL5 is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation:
The CXCL5 was lyophilized from a concentrated (1mg/ml) solution in water containing no additives.

Solubility:
It is recommended to reconstitute the lyophilized ENA-78 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability:
Lyophilized ENA78 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL5 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Purity:
Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Amino acid sequence:
The sequence of the first five N-terminal amino acids was determined and was found to be, Ala- Ala -Val-Leu-Arg.

Biological Activity:
The biological activity was determined by measuring the dose dependent mobilization of intracellular calcium (calcium flux) with human neutrophils. Significant calcium mobilization is observed with ≥100ng/mL of recombinant human ENA-78.

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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信用代码

310228001203103

成立日期

2009-05-31

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10

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Recombinant Human Epithelial Neutrophil-Activating Protein 78(CXCL5)由上海希美化学有限公司为您提供,货号CHM-331,规格:5µg,CAS号:,如您想了解更多关于Recombinant Human Epithelial Neutrophil-Activating Protein 78(CXCL5)价格、Recombinant Human Epithelial Neutrophil-Activating Protein 78(CXCL5)结构式、批发、用途等信息,欢迎咨询。除供应Recombinant Human Epithelial Neutrophil-Activating Protein 78(CXCL5)外,还可为您提供Recombinant Mouse Epithelial Neutrophil-Activating Protein 78(CXCL5)、人上皮中性粒细胞活化肽78(ENA-78/CXCL5)ELISA Kit、大鼠上皮中性粒细胞活化肽78(ENA-78/CXCL5)ELISA Kit等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海希美化学客户服务电话,售前、售后均可联系。
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