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当前位置: 上海希美化学 > 蛋白质/多肽 > 小鼠β防御素-1

小鼠β防御素-1

供货周期: 一周
品牌:
规格: 5ug
货号: cyt-044
CAS号:
报价: ¥800
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产品介绍
小鼠β防御素-1

Recombinant Mouse Beta Defensin -1(BD-1)






























































Catalogue Number

CYT-044

Synonyms

Beta-defensin 1, BD-1, Defensin beta 1, hBD-1, HBD1, HBP1, DEFB1, HBD-1, HBP-1, DEFB101, DEFB-1, MGC51822.

Introduction

The Defensin family are highly similar in their protein sequence and are microbicidal & cytotoxic peptides made by neutrophils. Beta Defensin-1 is an antimicrobial peptide having the resistance of epithelial surfaces to microbial colonization. Beta Defensin-1 has close proximity to Defensin Alpha-1 and has been implicated in the pathogenesis of cystic fibrosis.

Skin of patients having atopic dermatitis patients and mycosis fungoides (non-lesional and lesional) show lower human Beta Defensin-1 mRNA expression and higher human Beta Defensin-2 and human Beta Defensin-3 mRNA expression.

Beta Defensin is highly expressed by epithelial cells.

Beta-defensin 1 may play a role in the pathogenesis of severe sepsis.

Description

BD 1 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 37 amino acids and having a molecular mass of 4.1 KDa.

The BD 1 Mouse is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH7.4.

Solubility


It is recommended to reconstitute the lyophilized Mouse BD-1 in sterile 18M?-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.



Stability


Lyophilized Mouse BD 1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BD 1 should be stored at 4°C between 2-7 days and for future use below -18°C.

For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Please prevent freeze-thaw cycles.



Purity

Greater than 97.0% as determined by:

(a) Analysis by HPLC.

(b) Analysis by SDS-PAGE.

Amino acid sequence

DQYKCLQHGG FCLRSSCPSN TKLQGTCKPD KPNCCKS.

Biological Activity

Measured by its ability to chemoattract CD34+ dendritic cells using a concentration range of 0.1-1.0 ug/ml.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products











» BD 1 Human

» BD 1 Rat


工商信息

企业名称

上海希美化学有限公司

企业信息已认证

企业类型

信用代码

310228001203103

成立日期

2009-05-31

注册资本

10

经营范围

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小鼠β防御素-1由上海希美化学有限公司为您提供,货号cyt-044,规格:5ug,CAS号:,如您想了解更多关于小鼠β防御素-1价格、小鼠β防御素-1结构式、批发、用途等信息,欢迎咨询。除供应小鼠β防御素-1外,还可为您提供大鼠β防御素-1、小鼠β防御素-2、小鼠β防御素-3等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海希美化学客户服务电话,售前、售后均可联系。
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