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Atg5(ATG5)antibody
Cat.#: 3167-1
Rabbit Monoclonal Antibody
Clone ID: EPR1755(2)
Swiss Prot: Q9H1Y0
Mol Weight: 32/55kDa
Size: 100ul
Description
Atg5 (Autophagy protein 5) is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Atg5 may also play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity (1).
Recommended Applications
WB, IHC, ICC, IP
Applications and Recommended Dilution Factors
WB: 1:1,000 - 10,000
IHC: 1:100 - 250
ICC: 1:100 - 250
IP: 1:10 - 100
Species Reactivity
Human, Mouse, Rat
Mouse cross reactivity tested by western blot and IHC
Rat cross reactivity tested by western blot only
Products Data
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Western blot analysis on (A) Raji, (B) HeLa, (C) HT-1080, (D) fetal kidney, (E) C6, (F) Raw264.7, (G) PC-12, (H) NIH/3T3 cell lysates using anti-Atg5 RabMAb (cat. #3167-1).
Immunohistochemical analysis of paraffin-embedded human hepatocellular carcinoma tissue using anti-Atg5 RabMAb (cat. #3167-1).
Immunohistochemical analysis of paraffin-embedded human ovarian adenocarcinoma tissue using anti-Atg5 RabMAb (cat. #3167-1).
Specificity
A synthetic peptide corresponding to residues in human Atg5 was used as an immunogen.
Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Alternative Names
ATG5 antibody, APG5 antibody, APG5-LIKE antibody, APG5L antibody, ASP antibody, hAPG5 antibody, Autophagy protein 5 antibody, APG5-like antibody, Apoptosis-specific protein antibody
Description References
1. The UniProt Consortium. The Universal Protein Resource (UniProt). Nucleic Acids Res. 36:D190-D195 (2010)
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企业名称
上海希美化学有限公司
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企业类型
信用代码
310228001203103
成立日期
2009-05-31
注册资本
10
经营范围
化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海希美化学有限公司
公司地址
上海市松江区陆家圈路168弄113号
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公司名称： 上海希美化学有限公司
公司地址： 上海市松江区陆家圈路168弄113号 联系人： 李保平 邮编： 201619
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