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ACVR1B antibody
Cat.#: 3521-1
Rabbit Monoclonal Antibody
Clone ID: EPR4816
Swiss Prot: P36896
Mol Weight: 52kDa
Size: 100ul
Description
ACVR1B is an activin A type IB receptor. Activins are dimeric growth and differentiation factors that belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases, which include at least two type I and two type II receptors. ACVR1B is a type I receptor that is essential for signaling. Mutations in this protein are associated with pituitary tumors.
Recommended Applications
WB, FC
Applications and Recommended Dilution Factors
WB: 1:10,000-50,000
FC: 1:10 - 100
Species Reactivity
Human, Mouse, Rat
Species cross-reactivity is based on WB analysis
Products Data
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Western blot analysis on (A) HepG2, (B) SH-SY5Y, (C) U87-MG, and (D) 293T cell lysates using anti-ACVR1B RabMAb (cat. #3521-1).
Flow cytometric analysis of permeabilized 293T cells using anti-ACVR1B RabMAb (red) (catalog # 3521-1) or a rabbit IgG (negative) (green).
Specificity
A synthetic peptide corresponding to residues in the intracellular domain of human ACVR1B was used as an immunogen.
Storage Condition and Buffer
Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Alternative Names
ACVR1B antibody, ACTRIB antibody, ACVRLK4 antibody, ALK4 antibody, SKR2 antibody, Activin receptor type-1B antibody, Serine/threonine-protein kinase receptor R2 antibody
Description References
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8.
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企业名称
上海希美化学有限公司
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信用代码
310228001203103
成立日期
2009-05-31
注册资本
10
经营范围
化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海希美化学有限公司
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上海市松江区陆家圈路168弄113号
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公司名称： 上海希美化学有限公司
公司地址： 上海市松江区陆家圈路168弄113号 联系人： 李保平 邮编： 201619
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