采用经典的阳离子交换色谱分离、茚三酮柱后衍生法，对蛋白质水解液及各种游离氨基酸的组分含量进行分析。仪器基本结构同普通HPLC相似，但针对氨基酸分析进行了细节优化（例如氮气保护、惰性管路、在线脱气、洗脱梯度及柱温梯度控制等等， 现在有很多厂家生产氨基酸分析仪，如何选择，是使用者必须考虑的问题。

Phenylketonuria (PKU) is a genetic inborn error of metabolism, that is detectable during the first days of life with appropriate blood testing. The absence or deficiency of an enzyme that is responsible for processing the essential amino acid phenylalanine characterizes PKU. Without treatment, most infants with PKU develop mental retardation. Early detection of PKU can allow patient treatment to prevent mental retardation, as well as other associated problems. Treatment consists of a carefully-controlled pherestricted diet begun during the first days or weeks of life. Frequent blood monitoring of PKU patients is necessary, especially during infancy and early childhood when it is important to keep the blood phenylalanine levels at the safest level. Biochrom Amino Acid Analysers are widely used for the routine analysis of phenylalanine. Clinical laboratories have a continuous requirement for analyses of large numbers of samples. Rapid, accurate analysis is critical to meet the demand of the screening programmes. Improvements in peak resolution, accuracy, run times, and quantitation by using a dedicated instrument has enabled clinical laboratories to screen large numbers of samples per week. Using the Biochrom 30 Amino Acid Analyser phenylalanine can be rapidly and accurately quantified using norleucine as internal standard. The separation is carried out using a 20 cm x 4.6 mm high performance physiological column using buffer DII predominantly. The program enables 25 analyses to be performed a day. In addition tyrosine and homocystine are also well resolved thus enabling screening for the other metabolic diseases such as Tyronisis and Homocystinuria.

低钻井液水活度是有效进行"化学反渗透"防 塌措施的前提。利用Thennoconstanter Novasina 活 度仪测定了不同浓度和模数硅酸盐梅液的水活度。 实验结果表明，模数和加量对硅酸盐榕液的活度影 响不大。随放度增加，硅酸盐钻井液水活度略有降 低;随模数增大，钻井液水活度先增加后减小，介于 0.92 -0.95。