生物分子相互作用仪SPR200 OTSO

BioNavis生物分子相互作用分析仪应用领域再创新高度

BioNavis生物分子相互作用分析仪应用领域再创新高度，主要内容是有关BioNavis在生命科学、材料科学和传感器等领域的应用分析。

生物大分子相互作用分析仪SPR表征大面积的原子层石墨烯膜

用生物大分子相互作用分析仪SPR表征大面积的原子层石墨烯膜 SPR表征大面积的原子层石墨烯膜 详情请点击右上角：免费下载！ 生物大分子，分子间相互作用，表面等离子体共振，生物分子相互作用

AN # 140使用MP-SPR测量自组装金纳米粒子

Gold nanoparticles were immobilized on a monolayer self-assembled on gold. Functional groups on the chain ends of the monolayer facilitated an anchoring of gold nanoparticles to the layer. Multi-Parametric Surface Plasmon Resonance (MP-SPR) enabled a real-time measurement of the binding of the gold nanoparticles to the surface layer.

AN # 139使用MP-SPR表征脂质支持膜

Protein - antibody interactions are extremely important research area for pharmaceutical industry and protein research. Anti-body-based biotechnology drugs have been shown to be effective treatments to some obstinate diseases, like Bevacizumab for cancer therapy and Adalimumab for rheumatoid arthritis.

AN # 138使用MP-SPR测量抗体和抗原的相互作用

Introduction Protein - antibody interactions are extremely important research area for pharmaceutical industry and protein research. Anti-body-based biotechnology drugs have been shown to be effective treatments to some obstinate diseases, like Bevacizumab for cancer therapy and Adalimumab for rheumatoid arthritis.

AN#137使用MP-SPR测量药物与细胞单层的相互作用

Cell monolayer was deposited on a SPR sensor slide. Multi-Parametric Surface Plasmon Resonance (MP-SPR) was used to measure drugs (propranolol and D-mannitol) interaction with the cell monolayer in real time and in controlled flow conditions. It was possible to distinguish between paracellular and transcellular drug absorption routes.

AN#136使用MP-SPR监测聚合物坍塌和扩展

Cell monolayer was deposited on a SPR sensor slide. Multi-Parametric Surface Plasmon Resonance (MP-SPR) was used to measure drugs (propranolol and D-mannitol) interaction with the cell monolayer in real time and in controlled flow conditions. It was possible to distinguish between paracellular and transcellular drug absorption routes.

AN#135使用MP-SPR测量气体诱导的表面变化

MP-SPR instrument was used to characterize changes in a polymer film induced by different gases. Different humidities showed concentration dependent interaction with polymer and ethanol vapour seemed to penetrate to the polymer layer.

AN # 132通过MP-SPR测定功能层的结合能力

Clinical diagnostics is moving from centralized laboratories closer to the patient, into the doctor’s office, pharmacies, homes. The requirements for such point-of-care (POC) devices differ greatly from centralized laboratory demands. POC devices should provide low-cost and easy to use analytical tool for rapid analysis of analytes with clinical relevance. Many paper electronics opens up possibilities to do electronic platforms for cheap, disposable and recyclable applications that can be utilized in biosensing or medical diagnostic.

AN # 131使用MP-SPR技术的深扫描光学现象测定微米尺度层的光学特性和相互作用

Optical biosensor techniques based on evanescent field sensing, like surface plasmon resonance (SPR) have typically an effective detection depth of a hundred nanometers. For many coating-interaction studies coatings of this thickness can be difficult to achieve. Optical waveguides are phenomenon that can occur in structures able to capture and internally reflect light. A related optical phenomena, so-called SPR waveguide mode, might occur when between metal and the sample medium is a dielectric guiding layer with sufficiently high dielectric constant (ε) and thickness (d) (Fig. 1). The plasmon excitation by the visible light can be exited at several angles which are dependent on the whole optical system properties, and an angular spectrum of reflected light intensity (SPR-angular curve) will show several minima (Fig. 2).

AN#129生物分子间相互作用和靶向药物输送的流体力学效应的研究

Blood stream hydrodynamics is known to be an important pharmacokinetic factor that varies in different vessels and organs throughout the body. Liposomes are used in drug delivery systems to carry drug molecules to the effective site with some products already on the market. Liposomes are also widely studied as drug delivery systems for new drug targeting applica?tions. Multi Parametric Surface Plasmon Resonance (MP-SPR) is an in vitro label free method capable of providing information about interfacial adsorption events and molecular interaction kinetics. The SPR Navi 200 instrument′s open design allows easy custom?ization and control of the hydrodynamic conditions inside the measurement chamber. The Quartz Crystal Microbalance technique (QCM) senses the amount of water dynamically coupled to biomolecules, which is sometimes a useful additional information, but which can also be a complicating factor in assays. The difference in the hydrodynamic flow conditions for SPR and QCM