本实验使用擅长在中性条件下分析碱性化合物的CAPCELL PAK MGII色谱柱,按照客户指定方法对其所提供注射用泮托拉唑钠样品进行分析。首先,按照有关物质项下方法进行分析,结果如图1、2。泮托拉唑钠峰理论塔板数为173948,远超标准要求的2500;杂质A与泮托拉唑钠主峰得到良好分离,分离度为7.83。 其次,按照有关物质项下杂质D、F的色谱条件与系统适用性方法进行分析,结果如图3、4。泮托拉唑钠峰理论塔板数为18314,杂质D、F之间分离度为1.24,符合分离度不小于1.2的要求。 接下来,按照含量测定项下方法进行分析,结果如图5。泮托拉唑钠峰理论塔板数为20149,超过要求的2500。
Thanks to confocal Raman spectroscopy we have been able to investigate in vivo the epidermis chemical composition in its thickness. In depth measurements allowed us to observe modifications of the relative concentration of some components (water, proteins) depending on the depth in the skin and on its state of hydration.The use of larger numerical aperture objectives would be helpful to emphasize the in-depth variations because of the possible gain in axial resolution and therefore in-depth discrimination. Indeed, the operator could then probe in depth with a smaller step size.As a possible gain on the above measurements, the use of more powerful commercially available NIR diode lasers would yield up to ten times more laser power at the sample (60-80 mW) and would result in a tremendous improvement in terms of signal collection and integration time.?
Selective ablation of biological tissue and single cells on a glass substrate by controlling the laser energy density of nanosecond 193 nm laser radiation. J Anal At Spectrom. 2019 34(10):1957–64.通过控制纳秒 193 nm 激光辐射的激光能量密度选择性剥蚀玻璃基板上的生物组织和单个细胞