硬盘克隆机

最高克隆速度可达18GB/分钟&bull 支持SAS、SATA、IDE、USB接口设备的克隆&bull 最大支持&ldquo 三对三&rdquo 克隆&bull Linux DD、E01格式数据输出及还原克隆&bull 自动检测并获取磁盘HPA、DCO区域隐藏数据&bull 支持MD5、CRC32、SHA-1、SHA-2多种数据校验模式&bull 支持SHA-1、SHA-2(256)硬件加速校验，不影响克隆速度&bull 克隆过程可实时加密 AES 192/256&bull 双重擦除模式：DoD安全模式、快速模式&bull 证据硬盘接口内置硬件写保护技术，有效防止原始检材污染&bull 简体中文触摸屏智能向导操作 外部尺寸（毫米）：270x98x194重量：2.43kg供电电压：100-240V/50-60Hz设备功率：9W工作温度：5-55摄氏度相对湿度：20%-60% 扩展盒

该文库克隆试剂盒利用安捷伦的 SureVector 化学方法，可以从已扩增的寡核苷酸库中快速生成质粒文库。试剂盒包含安捷伦线性化的 pSGLenti 载体骨架、感受态细胞、培养基以及克隆安捷伦混合的可直接克隆或可直接扩增文库所需的所有缓冲液和试剂。pSGLenti 与安捷伦的可直接克隆文库兼容，而单独提供的其他骨架也可用于克隆完全定制的可直接扩增文库。每个试剂盒包含充足的上述物质，可生成 4 个含 60000 个向导的质粒文库。生成的质粒文库经过优化可用于哺乳动物细胞中，其表达由人 U6 启动子驱动SureVector 克隆技术适用于将定制文库插入慢病毒质粒 pSGLenti 中根据您的需求量身定制。联系我们 返回页首/SpecificationsSectionPageletTemplate --/TechnologySectionPageletTemplate --技术var x=document.querySelector(' i="0 i联系我们 返回页首/SpecificationsSectionPageletTemplate --/TechnologySectionPageletTemplate --技术var x=document.querySelector(' i="0 i 返回页首

克隆枪电穿孔系统备件是无绳可再充电的手持式电穿孔仪器，实现了超过50％的活细胞与各种标准的哺乳动物细胞系的转染效率。克隆枪电穿孔系统MammoZapper完全便携式手持式设计，使得转染变成一个简单的过程。只要插上我们的革命性的一次性Pipectrode® 移液电极尖端到MammoZapper就可实现。克隆枪电穿孔系统MammoZapper采用人体工程学精密拨轮操作泵提取你的细胞/ DNA混合物输入到Pipectrode，拉动触发器使混合物快速运动，将喷射出的转染物变成瓶- 完成全部不到15秒！与其他系统不同，我们Pipectrode使用过时比色皿和移液管，花时间来回转化细胞/ DNA混合物。与传统电穿孔仪，比色皿和脂质体转染试剂相比，克隆枪电穿孔系统MammoZapper及其Pipectrode室的成本更低，每美元的转染效率有很大提高。如果考虑时间和便捷，特别是在高通量实验中，提高的效率是真的很大。最后，对每个科学家来说，电穿孔是一个简单的低成本的过程。不需要为其他厂商提供的过时技术付更多的钱。用户在自己的工作台上就可以使用克隆枪电穿孔系统MammoZapper，或把污染敏感的样品放入无菌罩。克隆枪电穿孔系统MammoZapper采用独特的非离子型，最低限度导电，近等压电介质和超短脉冲时间，增加了转染效率和打击后物的成活力。我们通过做电穿孔研究推测电参数。克隆枪的电压和时间的参数进行了优化，帮助哺乳动物细胞研究得到良好结果，细胞包括来自人，小鼠，大鼠和猴（见下文）的神经元，星形细胞，神经胶质细胞，淋巴细胞，单核细胞，成纤维细胞，上皮细胞和内皮细胞。只要问我们是否我们已经用你最喜欢的细胞验证过，或是有克隆枪，然后自己选择产品（所有的Tritech研究产品有30天内退款保障）。指轮泵和Pipectrode® 电穿孔室比比色皿和移液管更加方便用户操作，我们保证克隆枪电穿孔系统MammoZapper是最有效和方便的电穿孔仪，带给您使用的乐趣。克隆枪电穿孔系统MammoZapper主要特点：Pipectrodes成本比比色皿低，转染率TE更高（与电离铝电极相比，减少了薄不锈钢电极的细胞毒性），也更环保。作为“一次性用品”出售，使用Pipectrodes能够比重复使用试管节省更多时间。不需要示波器去知道仪器是否在工作 - 简单的红色，黄色和绿色指示灯让用户知道，样品和DNA是否按照正常参数进行工作。比任何其他电穿孔设备至少快十倍。人体工程学设计。小巧便携，无绳/充电。使用它在自己的板凳上或在无菌罩！与其它的方法，电穿孔只介绍您感兴趣的分子（没有额外的钙，清洁剂，油脂，射弹，或病毒颗粒）。极高的转染效率无需复杂昂贵的病毒-介导程序。更可靠和普遍适用的比CaPO4共沉淀。并不需要昂贵的基于脂质的产品。比CaPO4共沉淀更可靠和普遍适用。不需要昂贵的基于脂质的产品。 高转染率

北京绿百草科技现货供应分离佐匹克隆的手性色谱柱CHIRALCEL OD系列色谱柱。佐匹克隆，英文名： ZOPICLONE CAPSULES，其化学名称为：6-(5-氯吡啶-2-基)-7-[(4-甲基哌嗪-1-基)羰氧基]-5,6-二氢吡咯[3,4-b]吡嗪-5-酮。佐匹克隆，镇静催眠药，用于治疗失眠症，尤其适用于不能耐受次晨残余作用的患者。绿百草科技可提供使用OD-H、 OD-R、 OD-RH进行手性拆分的详细操作条件和谱图。

Agilent Bio MAb 液相柱 填料担体由硬质球形、高度交联的聚苯乙烯二乙烯基苯（PS/DVB）无孔微球组成 填料表面结合了亲水聚合物层，避免抗体蛋白的非特异性结合 填料的弱阳离子交换固定相层采用了不同工艺，使其比Agilent Bio WCX 柱填料的密度更高 专为单克隆抗体基于带电异构体的分离而设计单克隆抗体的全面表征，包括酸性和碱性亚型的鉴定和监测。Agilent Bio MAb 液相柱填充了专为单克隆抗体基于带电量的高分离度分离而设计的特殊树脂。与水性缓冲液、乙腈/丙酮/甲醇和水混合溶液兼容。常用缓冲液为：磷酸盐、三羟甲基氨基甲烷、MES 和醋酸盐。Bio MAb 柱有1.7、3、5 和10 μm 粒径可供选择，较小的粒径能够提供较高的分离度。订货信息：

克隆枪电穿孔系统配件是全球领先的无绳可再充电的手持电穿孔仪器，可实现E大肠杆菌细菌的每微克DNA转染效率Transformation Efficiencies（TE）达到100亿以上。克隆枪电穿孔系统配件完全便携式手持式设计，只需将我们的革命性的一次性Pipectrode移液电极尖端插入克隆枪，转染成为一个简单的过程。克隆枪电穿孔系统BactoZapper采用人体工程学精密拨轮操作泵提取你的DNA混合后放入Pipectrode，触动按钮使其快速运转和喷射出转染物成琼脂平板- 全部完成不到15秒！与其他克隆枪电穿孔系统不同，我们的Pipectrode使用移液管来回转染DNA混合物。与传统电转仪，试管和化学感受态细胞比较，克隆枪电穿孔系统BactoZapper及其Pipectrode的成本更低，每美元的转染效率提高很大。如果考虑时间和便利，特别是在高通量实验中，效率提高是真的很大。最后，用超高分子量质粒（18 KB）工作时，电穿孔是唯一的方法。对每个科学家来说，电穿孔是一个简单的低成本的过程。不要为其他厂商提供的过时技术支付更多了。就在自己的工作台上，您可以使用BactoZapper，至于污染敏感的样品，把它放入无菌罩。克隆枪电穿孔系统BactoZapper克隆枪彻底改变了E大肠杆菌的转化。该克隆枪电穿孔系统出厂时为转化预先设置了最佳参数。转染效率（ TE），在收获阶段，输入DNA的每微克收获大于100亿个细胞。即使有标准的固定相细胞，用我们革命性的，超级简单的细胞制备的特色解决方案CompBooster® ，过夜培养超出109每微克。克隆枪电穿孔系统BactoZapper 的主要特点：Pipectrodes成本比试管少，转染效率（TE）更高（与电离铝电极相比，减少了薄不锈钢电极的细胞毒性），也更环保。作为“一次性”产品出售，Pipectrodes比重复使用许多次的试管能节省更多时间。不需要示波器显示是否在工作 - 简单的红色，黄色和绿色指示灯就能显示，你的样品和DNA是否按照正常参数进行工作。比任何其他电穿孔设备至少快十倍。人体工程学设计。小巧便携，无绳/充电。在自己的工作台上或在无菌罩里使用！与市售的感受态细胞相比，每次转化花费更少。与自制氯化钙细胞相比，转化效率高100倍以上，样品制备更快。可用于革命性的固定相细胞制备，可以使用简单的过夜培养产生每微克超过2×109个转化物。

可录式硬盘摄像机是将摄制的内容直接保存在内置硬盘上，并随时刻录到光碟中，或通过附带的USB传输线直接拷贝到计算机上。

玻璃的克隆环由高硼硅玻璃borosilicate glass 3.3制造，克隆环是筛选单克隆细胞的一个简单易行的方法，用克隆环可以有效的从培养板或者培养皿等培养耗材获得单克隆细胞。这种玻璃克隆环在应用时，首先将克隆环灭菌，用无菌硅脂实现克隆环的密封，然后用胰酶消化，以获取单克隆。其中无菌硅脂可以用甘油替代，甘油可以正常的高温高压灭菌。另外，建议使用水晶胰酶，可以在消化细胞时减少对细胞的伤害。塑料的克隆环无菌包装（PS制造），底部环略大于顶部，形成一定收缩口样子，可提供3种大小。订购信息：货号产品名称规格HG1980004克隆环（Cloning cylinders，Cloning rings）OD6mmX8mm100个/包HG1980003克隆环（Cloning cylinders，Cloning rings）OD8mmX8mm100个/包我们也提供实验过程中密封需要的硅脂，硅脂是必须选择的产品，如果您的手上没有！

产品特点：MAbPac™ SCX-10 RS 单克隆抗体分析柱，5 μm为了高分辨率、高效率地分析单克隆抗体 (mAb) 和相关变异体，请使用 Thermo Scientific™ MAbPac™ SCX-10 RS 单克隆抗体分析柱 (5 μm)。独特的无孔薄膜树脂可提供足以将差异仅为一个带电残基的 mAb 变体分离开来的分辨力。亲水层环绕在聚合物珠周围，可避免其与树脂发生疏水相互作用，从而可使色谱柱达到超高柱效。一种获得专利的接枝型阳离子交换表面可提供 pH 选择性控制功能，从而实现高分离度分离。mAb 变体分析性能卓越对 mAb 变体表现出超高分离度非常适合 mAb 的表征和质控评估特别适合用来进行稳定性研究、mAb 治疗方法开发和高通量筛选无与伦比的柱到柱和批到批的可重现性避免了在稳定性和 QA/QC 测试中对色谱柱变异性的担忧。符合生物制药表征的法规要求在标准规格和 UHPLC 规格中，可选粒径为 3 μm、5 μm 和 10 μm。粒径减小的色谱柱不但可提供与 10 μm 色谱柱相同的分离度，而且还能显著缩短分析时间。MAbPac SCX-10 RSBioRS (Rapid Separation), strong cation exchange column designed for monoclonal antibodies and associated charged variants* UHPLC, high throughput analysis* Specially developed bio-inert PEEK lined stainless steel column hardware *High pressure compatibility* Suitable for operation up to 7,000 psiHigher resolution and throughput of mAb charge variant UHPLC separations can be achieved using the MAbPac SCX-10 RS strong cation-exchange phase with specially developed bio-inert PEEK lined stainless steel column hardware. These columns are designed to be used at higher UHPLC conditions to maximize the resolution of mAb variant separation. Higher pressure compatibility of the column hardware allows use of high flow rates for faster separation.订购信息：MAbPac SCX-10RSParticle Size (μm)FormatLength (mm)2.1mm ID4.6mm ID5UHPLC Column50082675082674150088242085209250082515082673

集先进的高速硬盘克隆机功能与快速定向取证功能于一体，充分发挥Solo4高速硬盘克隆机的强大计算能力。精心部署eFreeZ定向取证工具。为一线电子取证办案人员提供更加快速、灵活的综合技术手段。功能组成硬件平台&bull 硬盘高速克隆，数据安全擦除 支持SAS、SATA、IDE、USB接口设备的直接克隆 克隆速度可达18GB/分钟、最大支持&ldquo 三对三&rdquo 克隆 克隆过程可实时加密 AES 192/256 支持MD5、CRC32、SHA-1、SHA-2多种数据校验模式 支持Linux DD、E01格式直接克隆及还原 自动检测并获取磁盘HPA、DCO区域隐藏数据 双重擦除模式：DoD安全模式、快速模式eFreeZ快速取证软件&bull 预制定向任务，快速现场实施 关键字、类型、属性等多种特征复合排查 系统信息、网络状态、聊天记录、邮件数据等定向获取 已删除文件自动恢复并提取&bull 强化搜索引擎，提高执行效率 自定义搜索，包括按照文件后缀，文件签名，时间属性，关键字等 数据挖掘能力，自动匹配查找任意路径下的邮件数据，我的文档等关键数据 自动获取当前用户的EFS文件，充分利用在线最佳获取时机 自动获取有打开口令的文档，如Word、Excel、PPT、PDF等&bull 安全取证设计，自动清理痕迹 完全无痕取证，不在目标计算机上遗留任何痕迹 突发任务中断处理，已经提取的数据、报告不受影响 自定义工作顺序，工作耗时提示，灵活取舍&bull 丰富取证模式，兼容多种系统 无需拆机，同时支持在线、离线双重取证模式 支持Windows XP/Vista /2003/2008/7及Linux、Mac（离线）&bull 外部尺寸（毫米）：270x98x194&bull 净重：2.43kg&bull 供电电压：100-240V/50-60Hz&bull 设备功率：9W&bull 工作温度：5-55摄氏度&bull 相对湿度：20%-60%

亲和色谱柱填料, 颗粒大小90 μm,适用于重组蛋白质，单克隆抗体

MAbPac SCX-10 RS 色谱柱BioRS, 用于单克隆抗体和相关变异体的强阳离子交换色谱柱 UHPLC，高通量分析 特殊开发的生物惰性的、PEEK衬里的不锈钢色谱柱管 兼容高压力 可在 7,000 psi 条件下使用使用小粒径的 MAbPac 强阳离子交换色谱柱以及特殊设计生物惰性的 PEEK 衬里的不锈钢柱管，可以实现MAb 变体的高分离度、高通量分析。该色谱柱使用更小粒径的色谱填料以及更长的柱子，提高 MAb 变体的分离度，可以在高达 7000 psi 的压力下进行分析。耐高压的柱管使快速分析变为可能。订货信息：

MAbPac SCX-10 RS 色谱柱BioRS, 用于单克隆抗体和相关变异体的强阳离子交换色谱柱 UHPLC，高通量分析 特殊开发的生物惰性的、PEEK衬里的不锈钢色谱柱管 兼容高压力 可在 7,000 psi 条件下使用使用小粒径的 MAbPac 强阳离子交换色谱柱以及特殊设计生物惰性的 PEEK 衬里的不锈钢柱管，可以实现MAb 变体的高分离度、高通量分析。该色谱柱使用更小粒径的色谱填料以及更长的柱子，提高 MAb 变体的分离度，可以在高达 7000 psi 的压力下进行分析。耐高压的柱管使快速分析变为可能。订货信息：

EGFR单克隆抗体的弱阳离子交换柱TSKgel CM-STAT，货号为21965、21966，粒径分别为7&mu m和10&mu m。TSKgel CM-STAT以无孔聚合物为基体，有3.0*35mm、4.6*100mm两种规格。TSKgel CM-STAT色谱柱机械性能稳定，可用于大多数生物聚合物分析，尤其是抗体的分离。绿百草科技可提供TSKgel CM-STAT分析抗EGFR单克隆抗体的操作条件和谱图。货号柱名称官能团类型粒径尺寸mm21960TSK gel Q-STAT季铵盐阴离子103*3521961TSK gel Q-STAT季铵盐阴离子74.6*10021962TSKgel DNA-STAT季铵盐阴离子54.6*10021963TSK gel SP-STAT磺酸基强阳103*3521964TSK gel SP-STAT磺酸基强阳74.6*10021965TSK gel CM-STAT羧酸基弱阳103*3521966TSK gel CM-STAT羧酸基弱阳74.6*100

绿百草科技专业提供色谱柱YMC-BioPro QA-F和YMC-Pack Diol200色谱柱分离单克隆抗体 关键词：YMC-BioPro QA-F，YMC-Pack Diol200，单克隆抗体，绿百草科技 绿百草科技专业提供YMC-BioPro QA-F离子交换色谱柱和YMC-Pack Diol-200凝胶柱。YMC-BioPro QA离子交换色谱柱可使用离子交换模式分离抗人体单克隆抗体；YMC-Pack Diol-300+Diol-200凝胶柱可使用体积排除（SEC）模式分离抗人体单克隆抗体。 需要详细的信息请和绿百草科技联系：010-51659766 登录网站获得更多产品信息:www.greenherbs.com.cn

突破传统电子物证检验手段的时效限制，无需克隆嫌疑硬盘，直接利用嫌疑计算机进行调查，还原系统真实软硬件环境，且不会造成任何硬盘数据的更改。技术特点&bull 原生IDE、SATA双通道支持&bull 外置缓冲硬盘，可灵活替换，轻松适配任何容量的原始检材&bull 安全只读保护原始检材硬盘&bull 完全透明于计算机硬件环境，操作简单，独立工作&bull 支持任何计算机操作系统，不留任何痕迹&bull 系统再现后，可直接安装并运行其它检验工具&bull 应用eDEC彩虹6，高速破解开机口令外部尺寸（毫米）：75 x 85 x 35功率：40瓦工作温度：5-55摄氏度相对湿度：20%-60%

本试剂盒可通过测定待测抗体与不同亚型特异性的抗体的结合情况，找出可以与待测抗体特异性结合的抗体，依据结合抗体的特异性可以得出待测抗体的亚型。本试剂盒可鉴定小鼠lgG抗体的不同亚型，包括lgG1、lgG2a、lgG2b、lgG3、lg4。与传统ELISA法相比，基于NanoSPR的芯片技术能够通过一步法，无标记快速区分抗体亚型。

穿孔室Pipectrode配件是电穿孔仪器的一项重大的技术进步。最高转化效率的最重要的决定因素是电穿孔过程中样品的低毒性，温度控制，及电穿孔后样品的迅速恢复。在电穿孔过程中，由水冰温度稳定剂支持的薄外科不锈钢电极为细胞的提供优越环境。我们利用水融合的潜热（融化1克冰或加热1克水到80℃，需要相同的热量！），保持样本的低温是非常重要的，这样可以避免电弧。由于Pipectrode是一个试管，可以喷射出您的样品并立即放入回收缓冲区。

Extrem A Diamond是博格隆自主研发的新一代高耐碱Protein A抗体亲和介质。蛋白A配基是在大肠杆菌中表达，与上一代产品AT Protein A Diamond Plus相比，耐碱性更强（可耐受0.5~1.0 M NaOH 的CIP）、载量更高。在工艺放大过程可以选择更小的柱体积来降低生产成本。适合从大批量细胞培养液中捕获单克隆抗体或者Fc融合蛋白，也适合于从腹水或者血浆中捕获多克隆抗体。该介质具有以下特点： 相同接触时间的情况下，较常规产品具有更高的动态结合能力。 蛋白配基的高耐碱性，可在清洗过程耐受0.5~1.0 M NaOH 的CIP。 载量高，能降低生产成本，提高生产效率。

AT Protein A Diamond Plus是一种新型的由耐碱Protein A同高刚性琼脂糖基架通过环氧化学方式合成的亲和介质，优化的介质孔径有利于提高抗体的结合载量，该介质适合从大批量细胞培养液中捕获单克隆抗体或者Fc融合蛋白，也适合于从腹水或者血浆中捕获多克隆抗体。 AT Protein A Diamond Plus的配基为基因工程重组的蛋白A片段，在上游构建的时候采用了耐碱的氨基酸替换了不耐碱的氨基酸，并且替换了蛋白酶敏感的氨基酸，使得该配基具有良好的碱稳定性，配基发酵及后续的纯化过程均采用无任何动物源原材料。该介质可以用0.1~0.5M NaOH进行在位清洗，避免了使用昂贵且具有腐蚀性的在位清洗试剂，可有效节省成本，同时和AT Protein A Diamond相比载量更高，在工艺放大过程可以选择更小的柱体积来降低生产成本。 该介质具有以下特点： 硬度高、反压低、流速快，适合大规模生产应用。 载量高，能降低生产成本。 耐受碱清洗，使用寿命长。

AT Protein A Diamond Ultra是一种新型的由耐碱Protein A同高刚性琼脂糖基架通过环氧化学方式合成的亲和介质，优化的介质孔径有利于提高抗体的结合载量，该介质适合从大批量细胞培养液中捕获单克隆抗体或者Fc融合蛋白，也适合于从腹水或者血浆中捕获多克隆抗体。 AT Protein A Diamond Ultra的配基为基因工程重组的蛋白A片段，在上游构建的时候采用了耐碱的氨基酸替换了不耐碱的氨基酸，并且替换了蛋白酶敏感的氨基酸，使得该配基具有良好的碱稳定性，配基发酵及后续的纯化过程均采用无任何动物源原材料。该介质可以用0.1~0.5M NaOH进行在位清洗，避免了使用昂贵且具有腐蚀性的在位清洗试剂，可有效节省成本，同时和AT Protein A Diamond Plus相比载量更高，在工艺放大过程可以选择更小的柱体积来降低生产成本。 该介质具有以下特点： 硬度高、反压低、流速快，适合大规模生产应用。 载量高，能降低生产成本。 耐受碱清洗，使用寿命长。

AT Protein A Diamond是一种由耐碱Protein A同高刚性琼脂糖基架通过环氧活化方式偶联后制成的一种新型亲和层析介质，与传统的抗体亲和介质相比，配基更稳定，流速更快，反压更低，适用于从大批量细胞培养液中捕获单克隆抗体或者Fc融合蛋白，也适合于从腹水或者血浆中捕获多克隆抗体。AT Protein A Diamond的配基为大肠杆菌发酵获得的重组蛋白A片段，在上游构建的时候采用耐碱的氨基酸替换了不耐碱的氨基酸，并且去除了蛋白酶敏感的氨基酸，使得该配基具有良好的碱稳定性，配基发酵及后续的纯化过程均采用无任何动物源原材料。该介质可以采用0.1~0.5M NaOH进行在位清洗，避免了使用昂贵且具有腐蚀性的清洗试剂，可有效节省成本，同时易于进行工业化大规模生产使用。

Novo-A Diamond是博格隆自主研发的新一代高耐碱Protein A抗体亲和介质。蛋白A配基是在大肠杆菌中表达，与上一代产品AT Protein A Diamond Plus相比，耐碱性更强，（可耐受0.5~1.0 M NaOH 的CIP）、压力流速性能更好。适合从大批量细胞培养液中捕获单克隆抗体或者Fc融合蛋白，也适合于从腹水或者血浆中捕获多克隆抗体。该介质具有以下特点： 相同接触时间的情况下，较常规产品具有更高的动态结合能力。 蛋白配基的高耐碱性，可在清洗过程耐受0.5~1.0 M NaOH 的CIP。 载量高，能降低生产成本，提高生产效率。

MAbPac SCX-10 Monoclonal Antibody Analysis ColumnMAbPac SCX-10 Columns for the High-Resolution Separation and Analysis of Monoclonal Antibody VariantsThe Thermo Scientific™ MAbPac™ SCX-10 column line has been expanded to include 3 and 5 μm particle sizes for fast, high-resolution analysis as well as rapid separation (RS) columns for bio-UHPLC separations. These smaller-particle-size columns provide the same high resolution as the 10 μm columns, but with significantly faster analysis time. In addition, salt or pH gradients can be used to provide fast high-resolution, high-throughput analysis of monoclonal antibody (MAb) variant samples.The MAbPac SCX-10 columns are strong cation-exchange columns designed specifically for the high-resolution, high-efficiency analysis of MAbs and associated variants. The unique nonporous pellicular resin provides exceptionally high resolving power, permitting the separation of MAb variants that differ by as little as one charged residue. Hydrophobic interactions with the resin are eliminated for very efficient peaks.Features:? Unequalled high-resolution separations? Exceptionally high efficiency? Highest resolution of MAb variants? Unmatched column-to-column and lot-to-lot reproducibility? Elimination of hydrophobic interactions? Ideal for stability testingThe MAbPac resin technology is the basis for the superior performance of MAb variant analysis. The nonporous core particle provides high rates of mass transfer, which results in high-efficiency separations. A hydrophilic layer surrounds the polymeric beads, eliminating hydrophobic interactions between proteins and the resin while contributing to high-efficiency peaks. A proprietary grafted cation-exchange surface provides pH selectivity control, resulting in high-resolution separations. In addition, the MAbPac SCX-10 line of columns provides consistent column-to-column and lot-to-lot reproducibility for MAb variant separation results and is ideal for MAb therapeutic method development and high-throughput screening. The MAbPac SCX-10 RS columns are designed for use with the Thermo Scientific™ Dionex™ UltiMate™ 3000 BioRS system. These columns are packed in bioinert, PEEK-lined, stainless steel column hardware suitable for operation up to 10,000 psi. These columns are higher efficiency, and therefore provide higher-resolution separations.MAbPac SCX-10 columns are designed to address the regulatory requirements for biopharmaceutical characterization. The consistent manufacturing processes ensure reproducibility in methods development and data analysis.The MAbPac SCX-10 column is complimentary to the industry-leading Thermo Scientific™ ProPac™ WCX-10 column for MAb variant analysis. The MAbPac SCX-10 column offers alternative selectivity and provides higher resolution and efficiency for variant analysis of most MAb samples than the ProPac WCX-10 column.New MAbPac SCX Column Kits for Validation Now AvailableThree MAbPac SCX-10, 4 × 250 mm columns from one lot of resinThree MAbPac SCX-10, 4 × 250 mm columns, one each from three lots of resinThese MAbPac SCX-10 column kits will facilitate the validation process of MAbPac SCX-10 columns for MAb therapeutics development projects.The MAbPac SCX-10, 10 μm, 9 × 250 mm column is now available for semipreparative applications of MAb variant separations.Fast High-Resolution Analysis of MAb variants achieved in only 15 minutes!MAbPac SCX-10 Monoclonal Antibody Analysis Column SpecificationsColumn Dimensions10 μm: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm, 2 × 250 mm5 μm Analytical: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm5 μm Analytical RS: 4.6 × 250 mm, 4.6 × 150 mm, 4.6 x 50mm, 2.1 x 250mm, 2.1 x 150mm, 2.1 x 250mm3 μm: 4 × 50 mmBead SizeUniform 10 μm, 5 μm, 3 μm particlesSubstrateHighly crosslinked DVB mediaPellicular LayerProprietary hydrophilicFunctional GroupSulfonicFlow Rate Range:0.2 to 2 mL/min for: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm0.1 to 0.5 ml/min for: 2 × 250 mmPressure Limit3,000 psi for 10 μm columns: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm5,000 psi for Analytical 3 μm and 5 μm columns7,000 psi for Analytical RS 5 μm columnsTemperature Range:Ambient to 60 oCpH Range2–12Typical buffers:Sodium or potassium salts of phosphate, MESSolvents:50% acetonitrile if needed for cleaningShort Term Storage Solution (overnight):Your low salt concentration eluent (pH 3–10)Shipping Solution / Long Term Storage Solution:20 mM MES (pH 5.6) + 60 mM NaCl– + 0.1% sodium azideDetergent CompatibilityNonionic, anionic, or zwitterionic detergents. MAbPac SCX-10 RS ColumnsMAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 50 mm)082674MAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 150 mm)085209MAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 250 mm)082673MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 50mm)082675MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 150mm)088242MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 250mm)082515Analytical ColumnsMAbPac SCX-10, 3μm, Analytical Column (4 x 50 mm)077907MAbPac SCX-10, 5μm, Analytical Column (4 x 50 mm)078656MAbPac SCX-10, 5μm, Analytical Column (4 x 150 mm)085198MAbPac SCX-10, 5μm, Analytical Column (4 x 250 mm)078655MAbPac SCX-10, 10 μm, Analytical Column (4 x 250mm)074625MAbPac SCX-10, 10μm, Analytical Column (4 x 150mm)075602MAbPac SCX-10HT, 10μm, Analytical Column (4 x 50mm)075603MAbPac SCX-10, 10μm, Analytical Column (2 x 250mm)075604MAbPac SCX-10, 10μm, 9 x 250 MM columnSP6866MAbPac SCX-10, 10μm, Lot Select 3 Column Set (4 x 250 mm) (1 Lot of Resin)SP6864MAPac SCX-10, 10μm, Lot Select 3 Column Set (4 x 250 mm) (3 Lots of Resin)SP6865Guard ColumnsMAbPac SCX-10G, 10μm, Guard Column (4 x 50 mm)074631MAbPac SCX-10G, 10μm, Guard Column (2 x 50 mm)075749

MAbPac SCX-10 Monoclonal Antibody Analysis ColumnMAbPac SCX-10 Columns for the High-Resolution Separation and Analysis of Monoclonal Antibody VariantsThe Thermo Scientific™ MAbPac™ SCX-10 column line has been expanded to include 3 and 5 μm particle sizes for fast, high-resolution analysis as well as rapid separation (RS) columns for bio-UHPLC separations. These smaller-particle-size columns provide the same high resolution as the 10 μm columns, but with significantly faster analysis time. In addition, salt or pH gradients can be used to provide fast high-resolution, high-throughput analysis of monoclonal antibody (MAb) variant samples.The MAbPac SCX-10 columns are strong cation-exchange columns designed specifically for the high-resolution, high-efficiency analysis of MAbs and associated variants. The unique nonporous pellicular resin provides exceptionally high resolving power, permitting the separation of MAb variants that differ by as little as one charged residue. Hydrophobic interactions with the resin are eliminated for very efficient peaks.Features:? Unequalled high-resolution separations? Exceptionally high efficiency? Highest resolution of MAb variants? Unmatched column-to-column and lot-to-lot reproducibility? Elimination of hydrophobic interactions? Ideal for stability testingThe MAbPac resin technology is the basis for the superior performance of MAb variant analysis. The nonporous core particle provides high rates of mass transfer, which results in high-efficiency separations. A hydrophilic layer surrounds the polymeric beads, eliminating hydrophobic interactions between proteins and the resin while contributing to high-efficiency peaks. A proprietary grafted cation-exchange surface provides pH selectivity control, resulting in high-resolution separations. In addition, the MAbPac SCX-10 line of columns provides consistent column-to-column and lot-to-lot reproducibility for MAb variant separation results and is ideal for MAb therapeutic method development and high-throughput screening. The MAbPac SCX-10 RS columns are designed for use with the Thermo Scientific™ Dionex™ UltiMate™ 3000 BioRS system. These columns are packed in bioinert, PEEK-lined, stainless steel column hardware suitable for operation up to 10,000 psi. These columns are higher efficiency, and therefore provide higher-resolution separations.MAbPac SCX-10 columns are designed to address the regulatory requirements for biopharmaceutical characterization. The consistent manufacturing processes ensure reproducibility in methods development and data analysis.The MAbPac SCX-10 column is complimentary to the industry-leading Thermo Scientific™ ProPac™ WCX-10 column for MAb variant analysis. The MAbPac SCX-10 column offers alternative selectivity and provides higher resolution and efficiency for variant analysis of most MAb samples than the ProPac WCX-10 column.New MAbPac SCX Column Kits for Validation Now AvailableThree MAbPac SCX-10, 4 × 250 mm columns from one lot of resinThree MAbPac SCX-10, 4 × 250 mm columns, one each from three lots of resinThese MAbPac SCX-10 column kits will facilitate the validation process of MAbPac SCX-10 columns for MAb therapeutics development projects.The MAbPac SCX-10, 10 μm, 9 × 250 mm column is now available for semipreparative applications of MAb variant separations.Fast High-Resolution Analysis of MAb variants achieved in only 15 minutes!MAbPac SCX-10 Monoclonal Antibody Analysis Column SpecificationsColumn Dimensions10 μm: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm, 2 × 250 mm5 μm Analytical: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm5 μm Analytical RS: 4.6 × 250 mm, 4.6 × 150 mm, 4.6 x 50mm, 2.1 x 250mm, 2.1 x 150mm, 2.1 x 250mm3 μm: 4 × 50 mmBead SizeUniform 10 μm, 5 μm, 3 μm particlesSubstrateHighly crosslinked DVB mediaPellicular LayerProprietary hydrophilicFunctional GroupSulfonicFlow Rate Range:0.2 to 2 mL/min for: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm0.1 to 0.5 ml/min for: 2 × 250 mmPressure Limit3,000 psi for 10 μm columns: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm5,000 psi for Analytical 3 μm and 5 μm columns7,000 psi for Analytical RS 5 μm columnsTemperature Range:Ambient to 60 oCpH Range2–12Typical buffers:Sodium or potassium salts of phosphate, MESSolvents:50% acetonitrile if needed for cleaningShort Term Storage Solution (overnight):Your low salt concentration eluent (pH 3–10)Shipping Solution / Long Term Storage Solution:20 mM MES (pH 5.6) + 60 mM NaCl– + 0.1% sodium azideDetergent CompatibilityNonionic, anionic, or zwitterionic detergents. MAbPac SCX-10 RS ColumnsMAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 50 mm)082674MAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 150 mm)085209MAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 250 mm)082673MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 50mm)082675MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 150mm)088242MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 250mm)082515Analytical ColumnsMAbPac SCX-10, 3μm, Analytical Column (4 x 50 mm)077907MAbPac SCX-10, 5μm, Analytical Column (4 x 50 mm)078656MAbPac SCX-10, 5μm, Analytical Column (4 x 150 mm)085198MAbPac SCX-10, 5μm, Analytical Column (4 x 250 mm)078655MAbPac SCX-10, 10 μm, Analytical Column (4 x 250mm)074625MAbPac SCX-10, 10μm, Analytical Column (4 x 150mm)075602MAbPac SCX-10HT, 10μm, Analytical Column (4 x 50mm)075603MAbPac SCX-10, 10μm, Analytical Column (2 x 250mm)075604MAbPac SCX-10, 10μm, 9 x 250 MM columnSP6866MAbPac SCX-10, 10μm, Lot Select 3 Column Set (4 x 250 mm) (1 Lot of Resin)SP6864MAPac SCX-10, 10μm, Lot Select 3 Column Set (4 x 250 mm) (3 Lots of Resin)SP6865Guard ColumnsMAbPac SCX-10G, 10μm, Guard Column (4 x 50 mm)074631MAbPac SCX-10G, 10μm, Guard Column (2 x 50 mm)075749

MAbPac SCX-10 Monoclonal Antibody Analysis ColumnMAbPac SCX-10 Columns for the High-Resolution Separation and Analysis of Monoclonal Antibody VariantsThe Thermo Scientific™ MAbPac™ SCX-10 column line has been expanded to include 3 and 5 μm particle sizes for fast, high-resolution analysis as well as rapid separation (RS) columns for bio-UHPLC separations. These smaller-particle-size columns provide the same high resolution as the 10 μm columns, but with significantly faster analysis time. In addition, salt or pH gradients can be used to provide fast high-resolution, high-throughput analysis of monoclonal antibody (MAb) variant samples.The MAbPac SCX-10 columns are strong cation-exchange columns designed specifically for the high-resolution, high-efficiency analysis of MAbs and associated variants. The unique nonporous pellicular resin provides exceptionally high resolving power, permitting the separation of MAb variants that differ by as little as one charged residue. Hydrophobic interactions with the resin are eliminated for very efficient peaks.Features:? Unequalled high-resolution separations? Exceptionally high efficiency? Highest resolution of MAb variants? Unmatched column-to-column and lot-to-lot reproducibility? Elimination of hydrophobic interactions? Ideal for stability testingThe MAbPac resin technology is the basis for the superior performance of MAb variant analysis. The nonporous core particle provides high rates of mass transfer, which results in high-efficiency separations. A hydrophilic layer surrounds the polymeric beads, eliminating hydrophobic interactions between proteins and the resin while contributing to high-efficiency peaks. A proprietary grafted cation-exchange surface provides pH selectivity control, resulting in high-resolution separations. In addition, the MAbPac SCX-10 line of columns provides consistent column-to-column and lot-to-lot reproducibility for MAb variant separation results and is ideal for MAb therapeutic method development and high-throughput screening. The MAbPac SCX-10 RS columns are designed for use with the Thermo Scientific™ Dionex™ UltiMate™ 3000 BioRS system. These columns are packed in bioinert, PEEK-lined, stainless steel column hardware suitable for operation up to 10,000 psi. These columns are higher efficiency, and therefore provide higher-resolution separations.MAbPac SCX-10 columns are designed to address the regulatory requirements for biopharmaceutical characterization. The consistent manufacturing processes ensure reproducibility in methods development and data analysis.The MAbPac SCX-10 column is complimentary to the industry-leading Thermo Scientific™ ProPac™ WCX-10 column for MAb variant analysis. The MAbPac SCX-10 column offers alternative selectivity and provides higher resolution and efficiency for variant analysis of most MAb samples than the ProPac WCX-10 column.New MAbPac SCX Column Kits for Validation Now AvailableThree MAbPac SCX-10, 4 × 250 mm columns from one lot of resinThree MAbPac SCX-10, 4 × 250 mm columns, one each from three lots of resinThese MAbPac SCX-10 column kits will facilitate the validation process of MAbPac SCX-10 columns for MAb therapeutics development projects.The MAbPac SCX-10, 10 μm, 9 × 250 mm column is now available for semipreparative applications of MAb variant separations.Fast High-Resolution Analysis of MAb variants achieved in only 15 minutes!MAbPac SCX-10 Monoclonal Antibody Analysis Column SpecificationsColumn Dimensions10 μm: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm, 2 × 250 mm5 μm Analytical: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm5 μm Analytical RS: 4.6 × 250 mm, 4.6 × 150 mm, 4.6 x 50mm, 2.1 x 250mm, 2.1 x 150mm, 2.1 x 250mm3 μm: 4 × 50 mmBead SizeUniform 10 μm, 5 μm, 3 μm particlesSubstrateHighly crosslinked DVB mediaPellicular LayerProprietary hydrophilicFunctional GroupSulfonicFlow Rate Range:0.2 to 2 mL/min for: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm0.1 to 0.5 ml/min for: 2 × 250 mmPressure Limit3,000 psi for 10 μm columns: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm5,000 psi for Analytical 3 μm and 5 μm columns7,000 psi for Analytical RS 5 μm columnsTemperature Range:Ambient to 60 oCpH Range2–12Typical buffers:Sodium or potassium salts of phosphate, MESSolvents:50% acetonitrile if needed for cleaningShort Term Storage Solution (overnight):Your low salt concentration eluent (pH 3–10)Shipping Solution / Long Term Storage Solution:20 mM MES (pH 5.6) + 60 mM NaCl– + 0.1% sodium azideDetergent CompatibilityNonionic, anionic, or zwitterionic detergents. MAbPac SCX-10 RS ColumnsMAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 50 mm)082674MAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 150 mm)085209MAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 250 mm)082673MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 50mm)082675MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 150mm)088242MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 250mm)082515Analytical ColumnsMAbPac SCX-10, 3μm, Analytical Column (4 x 50 mm)077907MAbPac SCX-10, 5μm, Analytical Column (4 x 50 mm)078656MAbPac SCX-10, 5μm, Analytical Column (4 x 150 mm)085198MAbPac SCX-10, 5μm, Analytical Column (4 x 250 mm)078655MAbPac SCX-10, 10 μm, Analytical Column (4 x 250mm)074625MAbPac SCX-10, 10μm, Analytical Column (4 x 150mm)075602MAbPac SCX-10HT, 10μm, Analytical Column (4 x 50mm)075603MAbPac SCX-10, 10μm, Analytical Column (2 x 250mm)075604MAbPac SCX-10, 10μm, 9 x 250 MM columnSP6866MAbPac SCX-10, 10μm, Lot Select 3 Column Set (4 x 250 mm) (1 Lot of Resin)SP6864MAPac SCX-10, 10μm, Lot Select 3 Column Set (4 x 250 mm) (3 Lots of Resin)SP6865Guard ColumnsMAbPac SCX-10G, 10μm, Guard Column (4 x 50 mm)074631MAbPac SCX-10G, 10μm, Guard Column (2 x 50 mm)075749

MAbPac SCX-10 Monoclonal Antibody Analysis ColumnMAbPac SCX-10 Columns for the High-Resolution Separation and Analysis of Monoclonal Antibody VariantsThe Thermo Scientific™ MAbPac™ SCX-10 column line has been expanded to include 3 and 5 μm particle sizes for fast, high-resolution analysis as well as rapid separation (RS) columns for bio-UHPLC separations. These smaller-particle-size columns provide the same high resolution as the 10 μm columns, but with significantly faster analysis time. In addition, salt or pH gradients can be used to provide fast high-resolution, high-throughput analysis of monoclonal antibody (MAb) variant samples.The MAbPac SCX-10 columns are strong cation-exchange columns designed specifically for the high-resolution, high-efficiency analysis of MAbs and associated variants. The unique nonporous pellicular resin provides exceptionally high resolving power, permitting the separation of MAb variants that differ by as little as one charged residue. Hydrophobic interactions with the resin are eliminated for very efficient peaks.Features:? Unequalled high-resolution separations? Exceptionally high efficiency? Highest resolution of MAb variants? Unmatched column-to-column and lot-to-lot reproducibility? Elimination of hydrophobic interactions? Ideal for stability testingThe MAbPac resin technology is the basis for the superior performance of MAb variant analysis. The nonporous core particle provides high rates of mass transfer, which results in high-efficiency separations. A hydrophilic layer surrounds the polymeric beads, eliminating hydrophobic interactions between proteins and the resin while contributing to high-efficiency peaks. A proprietary grafted cation-exchange surface provides pH selectivity control, resulting in high-resolution separations. In addition, the MAbPac SCX-10 line of columns provides consistent column-to-column and lot-to-lot reproducibility for MAb variant separation results and is ideal for MAb therapeutic method development and high-throughput screening. The MAbPac SCX-10 RS columns are designed for use with the Thermo Scientific™ Dionex™ UltiMate™ 3000 BioRS system. These columns are packed in bioinert, PEEK-lined, stainless steel column hardware suitable for operation up to 10,000 psi. These columns are higher efficiency, and therefore provide higher-resolution separations.MAbPac SCX-10 columns are designed to address the regulatory requirements for biopharmaceutical characterization. The consistent manufacturing processes ensure reproducibility in methods development and data analysis.The MAbPac SCX-10 column is complimentary to the industry-leading Thermo Scientific™ ProPac™ WCX-10 column for MAb variant analysis. The MAbPac SCX-10 column offers alternative selectivity and provides higher resolution and efficiency for variant analysis of most MAb samples than the ProPac WCX-10 column.New MAbPac SCX Column Kits for Validation Now AvailableThree MAbPac SCX-10, 4 × 250 mm columns from one lot of resinThree MAbPac SCX-10, 4 × 250 mm columns, one each from three lots of resinThese MAbPac SCX-10 column kits will facilitate the validation process of MAbPac SCX-10 columns for MAb therapeutics development projects.The MAbPac SCX-10, 10 μm, 9 × 250 mm column is now available for semipreparative applications of MAb variant separations.Fast High-Resolution Analysis of MAb variants achieved in only 15 minutes!MAbPac SCX-10 Monoclonal Antibody Analysis Column SpecificationsColumn Dimensions10 μm: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm, 2 × 250 mm5 μm Analytical: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm5 μm Analytical RS: 4.6 × 250 mm, 4.6 × 150 mm, 4.6 x 50mm, 2.1 x 250mm, 2.1 x 150mm, 2.1 x 250mm3 μm: 4 × 50 mmBead SizeUniform 10 μm, 5 μm, 3 μm particlesSubstrateHighly crosslinked DVB mediaPellicular LayerProprietary hydrophilicFunctional GroupSulfonicFlow Rate Range:0.2 to 2 mL/min for: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm0.1 to 0.5 ml/min for: 2 × 250 mmPressure Limit3,000 psi for 10 μm columns: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm5,000 psi for Analytical 3 μm and 5 μm columns7,000 psi for Analytical RS 5 μm columnsTemperature Range:Ambient to 60 oCpH Range2–12Typical buffers:Sodium or potassium salts of phosphate, MESSolvents:50% acetonitrile if needed for cleaningShort Term Storage Solution (overnight):Your low salt concentration eluent (pH 3–10)Shipping Solution / Long Term Storage Solution:20 mM MES (pH 5.6) + 60 mM NaCl– + 0.1% sodium azideDetergent CompatibilityNonionic, anionic, or zwitterionic detergents. MAbPac SCX-10 RS ColumnsMAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 50 mm)082674MAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 150 mm)085209MAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 250 mm)082673MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 50mm)082675MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 150mm)088242MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 250mm)082515Analytical ColumnsMAbPac SCX-10, 3μm, Analytical Column (4 x 50 mm)077907MAbPac SCX-10, 5μm, Analytical Column (4 x 50 mm)078656MAbPac SCX-10, 5μm, Analytical Column (4 x 150 mm)085198MAbPac SCX-10, 5μm, Analytical Column (4 x 250 mm)078655MAbPac SCX-10, 10 μm, Analytical Column (4 x 250mm)074625MAbPac SCX-10, 10μm, Analytical Column (4 x 150mm)075602MAbPac SCX-10HT, 10μm, Analytical Column (4 x 50mm)075603MAbPac SCX-10, 10μm, Analytical Column (2 x 250mm)075604MAbPac SCX-10, 10μm, 9 x 250 MM columnSP6866MAbPac SCX-10, 10μm, Lot Select 3 Column Set (4 x 250 mm) (1 Lot of Resin)SP6864MAPac SCX-10, 10μm, Lot Select 3 Column Set (4 x 250 mm) (3 Lots of Resin)SP6865Guard ColumnsMAbPac SCX-10G, 10μm, Guard Column (4 x 50 mm)074631MAbPac SCX-10G, 10μm, Guard Column (2 x 50 mm)075749

MAbPac SCX-10 Monoclonal Antibody Analysis ColumnMAbPac SCX-10 Columns for the High-Resolution Separation and Analysis of Monoclonal Antibody VariantsThe Thermo Scientific™ MAbPac™ SCX-10 column line has been expanded to include 3 and 5 μm particle sizes for fast, high-resolution analysis as well as rapid separation (RS) columns for bio-UHPLC separations. These smaller-particle-size columns provide the same high resolution as the 10 μm columns, but with significantly faster analysis time. In addition, salt or pH gradients can be used to provide fast high-resolution, high-throughput analysis of monoclonal antibody (MAb) variant samples.The MAbPac SCX-10 columns are strong cation-exchange columns designed specifically for the high-resolution, high-efficiency analysis of MAbs and associated variants. The unique nonporous pellicular resin provides exceptionally high resolving power, permitting the separation of MAb variants that differ by as little as one charged residue. Hydrophobic interactions with the resin are eliminated for very efficient peaks.Features:? Unequalled high-resolution separations? Exceptionally high efficiency? Highest resolution of MAb variants? Unmatched column-to-column and lot-to-lot reproducibility? Elimination of hydrophobic interactions? Ideal for stability testingThe MAbPac resin technology is the basis for the superior performance of MAb variant analysis. The nonporous core particle provides high rates of mass transfer, which results in high-efficiency separations. A hydrophilic layer surrounds the polymeric beads, eliminating hydrophobic interactions between proteins and the resin while contributing to high-efficiency peaks. A proprietary grafted cation-exchange surface provides pH selectivity control, resulting in high-resolution separations. In addition, the MAbPac SCX-10 line of columns provides consistent column-to-column and lot-to-lot reproducibility for MAb variant separation results and is ideal for MAb therapeutic method development and high-throughput screening. The MAbPac SCX-10 RS columns are designed for use with the Thermo Scientific™ Dionex™ UltiMate™ 3000 BioRS system. These columns are packed in bioinert, PEEK-lined, stainless steel column hardware suitable for operation up to 10,000 psi. These columns are higher efficiency, and therefore provide higher-resolution separations.MAbPac SCX-10 columns are designed to address the regulatory requirements for biopharmaceutical characterization. The consistent manufacturing processes ensure reproducibility in methods development and data analysis.The MAbPac SCX-10 column is complimentary to the industry-leading Thermo Scientific™ ProPac™ WCX-10 column for MAb variant analysis. The MAbPac SCX-10 column offers alternative selectivity and provides higher resolution and efficiency for variant analysis of most MAb samples than the ProPac WCX-10 column.New MAbPac SCX Column Kits for Validation Now AvailableThree MAbPac SCX-10, 4 × 250 mm columns from one lot of resinThree MAbPac SCX-10, 4 × 250 mm columns, one each from three lots of resinThese MAbPac SCX-10 column kits will facilitate the validation process of MAbPac SCX-10 columns for MAb therapeutics development projects.The MAbPac SCX-10, 10 μm, 9 × 250 mm column is now available for semipreparative applications of MAb variant separations.Fast High-Resolution Analysis of MAb variants achieved in only 15 minutes!MAbPac SCX-10 Monoclonal Antibody Analysis Column SpecificationsColumn Dimensions10 μm: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm, 2 × 250 mm5 μm Analytical: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm5 μm Analytical RS: 4.6 × 250 mm, 4.6 × 150 mm, 4.6 x 50mm, 2.1 x 250mm, 2.1 x 150mm, 2.1 x 250mm3 μm: 4 × 50 mmBead SizeUniform 10 μm, 5 μm, 3 μm particlesSubstrateHighly crosslinked DVB mediaPellicular LayerProprietary hydrophilicFunctional GroupSulfonicFlow Rate Range:0.2 to 2 mL/min for: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm0.1 to 0.5 ml/min for: 2 × 250 mmPressure Limit3,000 psi for 10 μm columns: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm5,000 psi for Analytical 3 μm and 5 μm columns7,000 psi for Analytical RS 5 μm columnsTemperature Range:Ambient to 60 oCpH Range2–12Typical buffers:Sodium or potassium salts of phosphate, MESSolvents:50% acetonitrile if needed for cleaningShort Term Storage Solution (overnight):Your low salt concentration eluent (pH 3–10)Shipping Solution / Long Term Storage Solution:20 mM MES (pH 5.6) + 60 mM NaCl– + 0.1% sodium azideDetergent CompatibilityNonionic, anionic, or zwitterionic detergents. MAbPac SCX-10 RS ColumnsMAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 50 mm)082674MAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 150 mm)085209MAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 250 mm)082673MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 50mm)082675MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 150mm)088242MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 250mm)082515Analytical ColumnsMAbPac SCX-10, 3μm, Analytical Column (4 x 50 mm)077907MAbPac SCX-10, 5μm, Analytical Column (4 x 50 mm)078656MAbPac SCX-10, 5μm, Analytical Column (4 x 150 mm)085198MAbPac SCX-10, 5μm, Analytical Column (4 x 250 mm)078655MAbPac SCX-10, 10 μm, Analytical Column (4 x 250mm)074625MAbPac SCX-10, 10μm, Analytical Column (4 x 150mm)075602MAbPac SCX-10HT, 10μm, Analytical Column (4 x 50mm)075603MAbPac SCX-10, 10μm, Analytical Column (2 x 250mm)075604MAbPac SCX-10, 10μm, 9 x 250 MM columnSP6866MAbPac SCX-10, 10μm, Lot Select 3 Column Set (4 x 250 mm) (1 Lot of Resin)SP6864MAPac SCX-10, 10μm, Lot Select 3 Column Set (4 x 250 mm) (3 Lots of Resin)SP6865Guard ColumnsMAbPac SCX-10G, 10μm, Guard Column (4 x 50 mm)074631MAbPac SCX-10G, 10μm, Guard Column (2 x 50 mm)075749

MAbPac SCX-10 Monoclonal Antibody Analysis ColumnMAbPac SCX-10 Columns for the High-Resolution Separation and Analysis of Monoclonal Antibody VariantsThe Thermo Scientific™ MAbPac™ SCX-10 column line has been expanded to include 3 and 5 μm particle sizes for fast, high-resolution analysis as well as rapid separation (RS) columns for bio-UHPLC separations. These smaller-particle-size columns provide the same high resolution as the 10 μm columns, but with significantly faster analysis time. In addition, salt or pH gradients can be used to provide fast high-resolution, high-throughput analysis of monoclonal antibody (MAb) variant samples.The MAbPac SCX-10 columns are strong cation-exchange columns designed specifically for the high-resolution, high-efficiency analysis of MAbs and associated variants. The unique nonporous pellicular resin provides exceptionally high resolving power, permitting the separation of MAb variants that differ by as little as one charged residue. Hydrophobic interactions with the resin are eliminated for very efficient peaks.Features:? Unequalled high-resolution separations? Exceptionally high efficiency? Highest resolution of MAb variants? Unmatched column-to-column and lot-to-lot reproducibility? Elimination of hydrophobic interactions? Ideal for stability testingThe MAbPac resin technology is the basis for the superior performance of MAb variant analysis. The nonporous core particle provides high rates of mass transfer, which results in high-efficiency separations. A hydrophilic layer surrounds the polymeric beads, eliminating hydrophobic interactions between proteins and the resin while contributing to high-efficiency peaks. A proprietary grafted cation-exchange surface provides pH selectivity control, resulting in high-resolution separations. In addition, the MAbPac SCX-10 line of columns provides consistent column-to-column and lot-to-lot reproducibility for MAb variant separation results and is ideal for MAb therapeutic method development and high-throughput screening. The MAbPac SCX-10 RS columns are designed for use with the Thermo Scientific™ Dionex™ UltiMate™ 3000 BioRS system. These columns are packed in bioinert, PEEK-lined, stainless steel column hardware suitable for operation up to 10,000 psi. These columns are higher efficiency, and therefore provide higher-resolution separations.MAbPac SCX-10 columns are designed to address the regulatory requirements for biopharmaceutical characterization. The consistent manufacturing processes ensure reproducibility in methods development and data analysis.The MAbPac SCX-10 column is complimentary to the industry-leading Thermo Scientific™ ProPac™ WCX-10 column for MAb variant analysis. The MAbPac SCX-10 column offers alternative selectivity and provides higher resolution and efficiency for variant analysis of most MAb samples than the ProPac WCX-10 column.New MAbPac SCX Column Kits for Validation Now AvailableThree MAbPac SCX-10, 4 × 250 mm columns from one lot of resinThree MAbPac SCX-10, 4 × 250 mm columns, one each from three lots of resinThese MAbPac SCX-10 column kits will facilitate the validation process of MAbPac SCX-10 columns for MAb therapeutics development projects.The MAbPac SCX-10, 10 μm, 9 × 250 mm column is now available for semipreparative applications of MAb variant separations.Fast High-Resolution Analysis of MAb variants achieved in only 15 minutes!MAbPac SCX-10 Monoclonal Antibody Analysis Column SpecificationsColumn Dimensions10 μm: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm, 2 × 250 mm5 μm Analytical: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm5 μm Analytical RS: 4.6 × 250 mm, 4.6 × 150 mm, 4.6 x 50mm, 2.1 x 250mm, 2.1 x 150mm, 2.1 x 250mm3 μm: 4 × 50 mmBead SizeUniform 10 μm, 5 μm, 3 μm particlesSubstrateHighly crosslinked DVB mediaPellicular LayerProprietary hydrophilicFunctional GroupSulfonicFlow Rate Range:0.2 to 2 mL/min for: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm0.1 to 0.5 ml/min for: 2 × 250 mmPressure Limit3,000 psi for 10 μm columns: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm5,000 psi for Analytical 3 μm and 5 μm columns7,000 psi for Analytical RS 5 μm columnsTemperature Range:Ambient to 60 oCpH Range2–12Typical buffers:Sodium or potassium salts of phosphate, MESSolvents:50% acetonitrile if needed for cleaningShort Term Storage Solution (overnight):Your low salt concentration eluent (pH 3–10)Shipping Solution / Long Term Storage Solution:20 mM MES (pH 5.6) + 60 mM NaCl– + 0.1% sodium azideDetergent CompatibilityNonionic, anionic, or zwitterionic detergents. MAbPac SCX-10 RS ColumnsMAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 50 mm)082674MAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 150 mm)085209MAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 250 mm)082673MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 50mm)082675MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 150mm)088242MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 250mm)082515Analytical ColumnsMAbPac SCX-10, 3μm, Analytical Column (4 x 50 mm)077907MAbPac SCX-10, 5μm, Analytical Column (4 x 50 mm)078656MAbPac SCX-10, 5μm, Analytical Column (4 x 150 mm)085198MAbPac SCX-10, 5μm, Analytical Column (4 x 250 mm)078655MAbPac SCX-10, 10 μm, Analytical Column (4 x 250mm)074625MAbPac SCX-10, 10μm, Analytical Column (4 x 150mm)075602MAbPac SCX-10HT, 10μm, Analytical Column (4 x 50mm)075603MAbPac SCX-10, 10μm, Analytical Column (2 x 250mm)075604MAbPac SCX-10, 10μm, 9 x 250 MM columnSP6866MAbPac SCX-10, 10μm, Lot Select 3 Column Set (4 x 250 mm) (1 Lot of Resin)SP6864MAPac SCX-10, 10μm, Lot Select 3 Column Set (4 x 250 mm) (3 Lots of Resin)SP6865Guard ColumnsMAbPac SCX-10G, 10μm, Guard Column (4 x 50 mm)074631MAbPac SCX-10G, 10μm, Guard Column (2 x 50 mm)075749

MAbPac SCX-10 Monoclonal Antibody Analysis ColumnMAbPac SCX-10 Columns for the High-Resolution Separation and Analysis of Monoclonal Antibody VariantsThe Thermo Scientific™ MAbPac™ SCX-10 column line has been expanded to include 3 and 5 μm particle sizes for fast, high-resolution analysis as well as rapid separation (RS) columns for bio-UHPLC separations. These smaller-particle-size columns provide the same high resolution as the 10 μm columns, but with significantly faster analysis time. In addition, salt or pH gradients can be used to provide fast high-resolution, high-throughput analysis of monoclonal antibody (MAb) variant samples.The MAbPac SCX-10 columns are strong cation-exchange columns designed specifically for the high-resolution, high-efficiency analysis of MAbs and associated variants. The unique nonporous pellicular resin provides exceptionally high resolving power, permitting the separation of MAb variants that differ by as little as one charged residue. Hydrophobic interactions with the resin are eliminated for very efficient peaks.Features:? Unequalled high-resolution separations? Exceptionally high efficiency? Highest resolution of MAb variants? Unmatched column-to-column and lot-to-lot reproducibility? Elimination of hydrophobic interactions? Ideal for stability testingThe MAbPac resin technology is the basis for the superior performance of MAb variant analysis. The nonporous core particle provides high rates of mass transfer, which results in high-efficiency separations. A hydrophilic layer surrounds the polymeric beads, eliminating hydrophobic interactions between proteins and the resin while contributing to high-efficiency peaks. A proprietary grafted cation-exchange surface provides pH selectivity control, resulting in high-resolution separations. In addition, the MAbPac SCX-10 line of columns provides consistent column-to-column and lot-to-lot reproducibility for MAb variant separation results and is ideal for MAb therapeutic method development and high-throughput screening. The MAbPac SCX-10 RS columns are designed for use with the Thermo Scientific™ Dionex™ UltiMate™ 3000 BioRS system. These columns are packed in bioinert, PEEK-lined, stainless steel column hardware suitable for operation up to 10,000 psi. These columns are higher efficiency, and therefore provide higher-resolution separations.MAbPac SCX-10 columns are designed to address the regulatory requirements for biopharmaceutical characterization. The consistent manufacturing processes ensure reproducibility in methods development and data analysis.The MAbPac SCX-10 column is complimentary to the industry-leading Thermo Scientific™ ProPac™ WCX-10 column for MAb variant analysis. The MAbPac SCX-10 column offers alternative selectivity and provides higher resolution and efficiency for variant analysis of most MAb samples than the ProPac WCX-10 column.New MAbPac SCX Column Kits for Validation Now AvailableThree MAbPac SCX-10, 4 × 250 mm columns from one lot of resinThree MAbPac SCX-10, 4 × 250 mm columns, one each from three lots of resinThese MAbPac SCX-10 column kits will facilitate the validation process of MAbPac SCX-10 columns for MAb therapeutics development projects.The MAbPac SCX-10, 10 μm, 9 × 250 mm column is now available for semipreparative applications of MAb variant separations.Fast High-Resolution Analysis of MAb variants achieved in only 15 minutes!MAbPac SCX-10 Monoclonal Antibody Analysis Column SpecificationsColumn Dimensions10 μm: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm, 2 × 250 mm5 μm Analytical: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm5 μm Analytical RS: 4.6 × 250 mm, 4.6 × 150 mm, 4.6 x 50mm, 2.1 x 250mm, 2.1 x 150mm, 2.1 x 250mm3 μm: 4 × 50 mmBead SizeUniform 10 μm, 5 μm, 3 μm particlesSubstrateHighly crosslinked DVB mediaPellicular LayerProprietary hydrophilicFunctional GroupSulfonicFlow Rate Range:0.2 to 2 mL/min for: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm0.1 to 0.5 ml/min for: 2 × 250 mmPressure Limit3,000 psi for 10 μm columns: 4 × 250 mm, 4 × 150 mm, 4 × 50 mm5,000 psi for Analytical 3 μm and 5 μm columns7,000 psi for Analytical RS 5 μm columnsTemperature Range:Ambient to 60 oCpH Range2–12Typical buffers:Sodium or potassium salts of phosphate, MESSolvents:50% acetonitrile if needed for cleaningShort Term Storage Solution (overnight):Your low salt concentration eluent (pH 3–10)Shipping Solution / Long Term Storage Solution:20 mM MES (pH 5.6) + 60 mM NaCl– + 0.1% sodium azideDetergent CompatibilityNonionic, anionic, or zwitterionic detergents. MAbPac SCX-10 RS ColumnsMAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 50 mm)082674MAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 150 mm)085209MAbPac SCX-10 RS, 5μm, Analytical Column (4.6 x 250 mm)082673MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 50mm)082675MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 150mm)088242MAbPac SCX-10 RS, 5μm, Analytical Column (2.1 x 250mm)082515Analytical ColumnsMAbPac SCX-10, 3μm, Analytical Column (4 x 50 mm)077907MAbPac SCX-10, 5μm, Analytical Column (4 x 50 mm)078656MAbPac SCX-10, 5μm, Analytical Column (4 x 150 mm)085198MAbPac SCX-10, 5μm, Analytical Column (4 x 250 mm)078655MAbPac SCX-10, 10 μm, Analytical Column (4 x 250mm)074625MAbPac SCX-10, 10μm, Analytical Column (4 x 150mm)075602MAbPac SCX-10HT, 10μm, Analytical Column (4 x 50mm)075603MAbPac SCX-10, 10μm, Analytical Column (2 x 250mm)075604MAbPac SCX-10, 10μm, 9 x 250 MM columnSP6866MAbPac SCX-10, 10μm, Lot Select 3 Column Set (4 x 250 mm) (1 Lot of Resin)SP6864MAPac SCX-10, 10μm, Lot Select 3 Column Set (4 x 250 mm) (3 Lots of Resin)SP6865Guard ColumnsMAbPac SCX-10G, 10μm, Guard Column (4 x 50 mm)074631MAbPac SCX-10G, 10μm, Guard Column (2 x 50 mm)075749