![1.png 1.png](https://img1.17img.cn/17img/images/201906/uepic/d13c6712-03e2-43bf-8f7d-f7d9438be7a4.jpg)
丝裂原活化蛋白激酶激酶2单克隆抗体
英文名称 MEK2
中文名称 丝裂原活化蛋白激酶激酶2单克隆抗体
别 名 Cardiofaciocutaneous syndrome; CFC syndrome; Dual specificity mitogen activated protein kinase kinase 2; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; FLJ26075; MAP kinase kinase 2; MAP2K 2; map2k2; MAPK / ERK kinase 2; MAPK/ERK kinase 2; MAPKK 2; MAPKK2; MEK 2; MEK2; Microtubule Associated Protein Kinase Kinase 2; Mitogen activated protein kinase kinase 2; Mitogen activated protein kinase kinase 2 p45; MKK 2; MKK2; MP2K2_HUMAN; OTTHUMP00000165826; OTTHUMP00000165827; PRKMK 2; PRKMK2 V.
研究领域 肿瘤 细胞生物 免疫学 神经生物学 信号转导 激酶和磷酸酶
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 4C3
交叉反应 Human, Mouse, Rat,
产品应用 WB=1:1000-2000 IHC-P=1:200-1000 IHC-F=1:200-1000 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
细胞定位 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/ml
免 疫 原 Recombinant human MEK2 Protein:
亚 型 IgG
纯化方法 affinity purified by Protein G
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008].
丝裂原活化蛋白激酶激酶(MAPKK)是信号转导途径中的重要成员。
丝裂原活化蛋白激酶激酶2单克隆抗体信息由上海联迈生物工程有限公司为您提供,如您想了解更多关于丝裂原活化蛋白激酶激酶2单克隆抗体报价、型号、参数等信息,欢迎来电或留言咨询。除供应丝裂原活化蛋白激酶激酶2单克隆抗体外,上海联迈生物工程有限公司还可为您提供热休克蛋白90α单克隆抗体、磷酸化酪氨酸单克隆抗体、环腺苷酸应答元件结合蛋白单克隆抗体等产品,公司有专业的客户服务团队,是您值得信赖的合作伙伴。