核纤层蛋白B单克隆抗体(细胞核膜标志物)

核纤层蛋白B单克隆抗体(细胞核膜标志物)

英文名称    Lamin B    

中文名称    核纤层蛋白B单克隆抗体(细胞核膜标志物)    

别    名    lamin B1; LMB1; LMN; LMN2; LMNB 1; LMNB; LMNB1; MGC111419; LMNB1_HUMAN; Lamin-B1.      

产品类型    内参抗体     

研究领域    细胞生物  染色质和核信号  信号转导  细胞凋亡  细胞类型标志物      

抗体来源    Mouse    

克隆类型    Monoclonal    

克 隆 号    9C11    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:500-1000 ELISA=1:500-1000  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    64kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    Recombinant human Lamin B Protein:     

亚    型    IgG1    

纯化方法    affinity purified by Protein G    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq, Oct 2010].