胰淀粉酶抗体

胰淀粉酶抗体

英文名称    Pancreatic Amylase    

中文名称    胰淀粉酶抗体    

别    名    Alpha amylase; Alpha amylase pancreatic precursor; AMY2; AMY2A; AMY2B; Amylase alpha 2A; Amylase alpha 2A pancreatic; Amylase alpha 2B; Amylase alpha 2B pancreatic; Amylase pancreatic alpha 2A; Amylase pancreatic alpha 2B; Pancreatic alpha amylase; AMYP_HUMAN.      

研究领域    肿瘤  细胞生物  免疫学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    56kDa    

细胞定位    细胞外基质 分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Pancreatic Amylase:151-250/511     

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    Pancreatic amylase is a digestive enzyme secreted by the pancreas. It consists of a single polypeptide chain with a molecular weight of 54 kDa.Pancreatic amylase and salivary amylase are the products of separate genes and, although they share 98% amino acid sequence homology, they differ in molecular size, isoelectric point and antigenic properties. Measurement of amylase concentrations in serum is a diagnostic test for various pancreatic disorders (especially acute and relapsing pancreatitis).    

胰淀粉酶由胰腺以活性状态排入消化道，是最重要的水解碳水化合物的酶，和唾液腺分泌的淀粉酶一样都属于α-淀粉酶，作用于α-1，4糖苷键，对分支上的α-1，6糖苷键无作用，故又称淀粉内切酶，其作用的最适pH为6.9，可通过肾小球滤过，是一能在正常时于尿中出现的血浆酶。
    人体的其他组织如卵巢、输卵管、肺、睾丸、精液、乳腺等的提取物中都发现有淀粉酶活性;血液、尿液、乳液中也含淀粉酶。血液淀粉酶中主要来自胰腺、唾液腺，尿液中淀粉酶则来自于血液.。当罹患胰腺疾病，或有胰腺外分泌功能障碍时都可引起其活性升高或降低，有助于胰腺疾病的诊断。尿淀粉酶水平波动较大，所以用血清淀粉酶检测为好，或两者同时测定。淀粉酶活性变化亦可见于某些非胰腺疾患。