有丝分裂激酶B抗体

有丝分裂激酶B抗体

英文名称    Aurora B    

中文名称    有丝分裂激酶B抗体    

别    名    STK-1; serine/threonine kinase 12; aurora-B; aurora-1; aurora kinase B-Sv1; aurora kinase B-Sv2; ARK-2; STK-1; STK1; aurora-related kinase 2; aurora/IPL1-related kinase 2; serine/threonine-protein kinase aurora-B; aurora- and Ipl1-like midbody-associated protein 1; AURKB; AIK2; AIM-1; AIM1; ARK2; AurB; aurkb-sv1; aurkb-sv2; IPL1; STK12; STK5; AIRK2; AURKB_HUMAN.      

研究领域    肿瘤  细胞生物  神经生物学  信号转导  细胞周期蛋白  激酶和磷酸酶      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:500-2000 ELISA=1:500-1000 Flow-Cyt=3ug/Test  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    39kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Aurora B:51-150/344     

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromsomes 19 and 20. These kinases participate in the regulation of segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].    

细胞的有丝分裂是生物体最基本的生命活动过程,能将复制的基因组精确地分配到下一代子细胞中,在长期的生物进化过程中，生物体形成了一整套完善的监测机制以确保遗传物质精确地分配到子细胞中。
Aurora激酶(极光激酶)是细胞有丝分裂调控网络中的一类重要的丝氨酸/苏氨酸激酶，Aurora酪氨酸激酶B也是丝氨酸/苏氨酸激酶家族成员之一，目前分为aurora A，B及C。