微管蛋白α 1A/1B抗体

微管蛋白α 1A/1B抗体

英文名称    Tubulin alpha    

中文名称    微管蛋白α 1A/1B抗体    

别    名    TUBA1A + TUBA1B; Tubulin, Alpha 1b; Tubulin Alpha-Ubiquitous Chain; Alpha-Tubulin Ubiquitous; Tubulin K-Alpha-1; Tubulin, Alpha, Ubiquitous; Tubulin Alpha-1B Chain; Alpha Tubulin; Ubiquitous; K-ALPHA-1; Tubulin Alpha; TBA1B_HUMAN; Tubulin, Alpha 1a; TUBA3; Tubulin Alpha-3 Chain; Tubulin B-Alpha-1; LIS3; Tubulin, Alpha, Brain-Specific; Tubulin Alpha-1A Chain; Alpha-Tubulin 3, Brain-Specific; Hum-A-Tub1; Hum-A-Tub2; B-ALPHA-1; TBA1A_HUMAN;       

产品类型    内参抗体     

研究领域    细胞生物  免疫学  细胞骨架      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Pig, Cow,     

产品应用    WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    50kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/ml    

免 疫 原    KLH conjugated synthetic peptide derived from human TUBA1A + TUBA1B:401-451/451     

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

PubMed    PubMed    

产品介绍    Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]