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Reversed-Phase and Weak Anion-Exchange Properties on a Single Column
The novel column chemistry of the Acclaim® Mixed-Mode WAX-1 results in a multimode separation mechanism including hydrophobic, anion-exchange, and cation-exclusion interactions. Consequently, retention of basic, neutral, and acidic molecules can be either independently or concurrently adjusted by changing ionic strength, pH, and organic solvent content in the mobile phase.
Adjustable selectivity
Selectivity orthogonal to reversed-phase (RP) columns
Ideal selectivity for anionic molecules
Simultaneous separation of acidic, basic, and neutral molecules
Multimode retention mechanisms: reversed- and normal phase, anion-exchange, cation-exclusion, and HILIC modes
The Acclaim Mixed-Mode WAX-1 column combines hydrophobic and anion-exchange characteristics, on a 5 μm high-purity, porous silica with 120-? diameter pores. Because of this unique chemistry, the Acclaim Mixed-Mode WAX-1 column also provides complimentary selectivity to C18 reversed-phase columns.
Hydrophilic organic acids are often difficult to separate with common RP columns, since hydrophobic retention alone is inadequate to differentiate molecules with similar hydrophobicities. This can be overcome using the Acclaim Mixed-Mode WAX-1 column; it provides sufficient retention, and ideal selectivity for a variety of anionic molecules, even for weakly charged molecules.
Multi-Mode Separation Mechanism
Retention of basic, neutral and acidic molecules can be either independently or concurrently adjusted by changing ionic strength, pH, and organic solvents content in the mobile phase. The presence of anion-exchange functionality control through electrostatic attraction (anions), repulsion (cations). The alkyl chain controls separation by hydrophobic interaction.
A broad range of samples in the pharmaceutical, food and beverage and chemical industries can be separated. Separation of basic active ingredients and its counter-ion can be simultaneously determined, as well as separation of ingredients containing basic, neutral, and acidic ingredients.
| Acclaim Mixed-Mode WAX-1 Columns: A simple solution to difficult separations Specifications | |
|---|---|
| Column Chemistry | Alkyl amine |
| Base silica | Spherical, high-purity |
| Particle size | 5 μm |
| Pore size | 120 ? |
| Surface area | 300 m2/g |
| Analytical Columns | |
|---|---|
| Acclaim Mixed-Mode WAX-1, 3μm Analytical, (3.0 x 150mm) | 070088 |
| Acclaim Mixed-Mode WAX-1, 3μm Analytical, (3.0 x 50mm) | 071908 |
| Acclaim Mixed-Mode WAX-1, 3μm Analytical, (2.1 x 150mm) | 070089 |
| Acclaim Mixed-Mode WAX-1, 5 μm (4.6 x 150 mm) | 064984 |
| Acclaim Mixed-Mode WAX-1, 5 μm (4.6 x 250 mm) | 064985 |
| Acclaim Mixed-Mode WAX-1, 5 μm, 2.1 x 150 mm | 067084 |
| Guard Columns | |
|---|---|
| Acclaim Mixed-Mode WAX-1, 5 μm Guard Cartridges (4.6 x 10 mm), 2 ea (use V-2 Holder) | 069704 |
| Acclaim Mixed-Mode WAX-1, 5μm Guards (3 x 10mm), 2ea, requires holder 069580 | 071909 |
| Acclaim Mixed-Mode WAX-1, 5μm, Guards (2.1 x 10mm), 2 ea; requires holder 069580 | 069686 |
| Acclaim SST Guard Cartridge Holder V-2 | 069580 |
| Acclaim Guard Kit (Holder and coupler) V-2 | 069707 |
| Guard to Analytical Column Coupler V-2 | |
企业名称
上海希言科学仪器有限公司
企业信息已认证
企业类型
有限责任公司(自然人投资或控股)
信用代码
91310117301434080L
成立日期
2014-05-26
注册资本
人民币100.0000万元整
经营范围
一般项目:技术服务、技术开发、技术咨询、技术交流、技术转让、技术推广;仪器仪表销售;实验分析仪器销售;光学仪器销售;货物进出口;技术进出口。(除依法须经批准的项目外，凭营业执照依法自主开展经营活动)
上海希言科学仪器有限公司
公司地址
上海市松江区九亭镇涞寅路1025号立同国际商务大厦3067室
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