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GlycanPac AXR-1 Glycan Analysis Column
GlycanPac AXR-1 Columns for the High-Resolution Separation and Analysis of Glycans
The Thermo Scientific™ GlycanPac™ AXR-1 column is a high-performance, silica-based HPLC column for the simultaneous separation of glycans by charge, isomerism, and size. It is designed to provide industry-leading resolution with unique selectivities for biologically important glycans, either labeled or native, using either fluorescence and/or mass spectrometry (MS) detection.
Features:
? Unique glycan selectivity based on charge, branch/linkage isomerism, and size
? Exceptional resolution for either native or derivatized glycans
? Utility for both high-resolution glycan structural characterization and glycan quantification
? Compatibility with both MS and fluorescence detection methods
? Reliable column performance
? Available in HPLC (3 μm) and UHPLC (1.9 μm) formats.
The GlycanPac AXR-1 column, based on innovative, mixed-mode surface chemistry, combines both weak anion-exchange (WAX) and reversed-phase interaction mechanisms to produce exceptional glycan selectivity and industry-leading resolution. The WAX functionality provides retention of negatively charged glycans that elute in order of increasing charge, and the reversed-phase mode facilitates resolution of glycans of the same charge according to their isomerism and size. These attributes produce unparalleled glycan separations. The GlycanPac AXR-1 column is designed for HPLC and UHPLC methods using either fluorescence or MS detection, and uses volatile aqueous buffers (e.g., ammonium acetate or ammonium formate) and acetonitrile, presenting the eluting glycans ready for introduction into MS instruments.
GlycanPac AXR-1 columns are based on high-purity and spherical silica substrates in both 1.9 and 3 μm sizes for UHPLC and standard HPLC applications, respectively. GlycanPac AXR-1 columns are available in various dimensions for applications with different resolutions, throughput, and instrument requirements.
| GlycanPac AXR-1 Column Specifications | |
|---|---|
| Column Dimensions | 1.9 μm: 2.1 × 250mm, 2.1 × 150mm 3 μm: 4.6 × 150mm, 3.0 × 150mm, 2.1 × 150mm |
| Particle Size | Spherical 1.9 μm, 3 μm particles |
| Substrate | High-purity, Porous, Spherical Silica |
| Surface Area | 220 m2/g |
| Pore size | 175 ? |
| Functional Group | WAX and RP Mixed-Mode |
| Recommended Flow Rate Range: | 1.9 μm: 0.2 to 0.4 mL/min. for: all 2.1 mm columns 3 μm: 0.8 to 1.2 ml/min for 4.6 × 150 mm 0.3 to 0.6 ml/min for 3.0 × 150 mm 0.1 to 0.3 ml/min. for 2.1 × 150 mm |
| Pressure Limit | 1.9 μm: 10,000 psi for 2.1 ×150mm 15,000 psi for 2.1 × 250mm 3 μm: 6,000 psi for all 3 μm columns |
| Temperature Range: | Ambient to < 60 oC |
| pH Range | 2.0 - 8.0 |
| Analytical Columns | |
|---|---|
| GlycanPac AXR-1, Analytical, 1.9μm, 2.1x150mm | 088136 |
| GlycanPac AXR-1, Analytical, 1.9μm, 2.1x250mm | 088135 |
| GlycanPac AXR-1, Analytical, 3.0μm, 2.1x150mm | 088251 |
| GlycanPac AXR-1, Analytical, 3.0μm, 3.0x150mm | 088252 |
| GlycanPac AXR-1, Analytical, 3.0μm, 4.6 x150mm | 088255 |
| Guard Columns | |
|---|---|
| GlycanPac AXR-1, Guard, 3.0μm, 2.1 x10mm,2EA | 088258 |
| GlycanPac AXR-1, Guard, 3.0μm, 3.0 x10mm,2EA | 088259 |
| GlycanPac AXR-1, Guard, 3.0μm, 4.6 x10mm,2EA | 088260 |
| Acclaim SST Guard Cartridge Holder V-2 | 069580 |
| Acclaim Guard Kit (Holder and coupler) V-2 | 069707 |
| Guard to Analytical Column Coupler V-2 | |
企业名称
上海希言科学仪器有限公司
企业信息已认证
企业类型
有限责任公司(自然人投资或控股)
信用代码
91310117301434080L
成立日期
2014-05-26
注册资本
人民币100.0000万元整
经营范围
一般项目:技术服务、技术开发、技术咨询、技术交流、技术转让、技术推广;仪器仪表销售;实验分析仪器销售;光学仪器销售;货物进出口;技术进出口。(除依法须经批准的项目外，凭营业执照依法自主开展经营活动)
上海希言科学仪器有限公司
公司地址
上海市松江区九亭镇涞寅路1025号立同国际商务大厦3067室
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