Quantity size:
0.2ml
Concentration:
1mg/ml DNA拓扑异构酶2-β/TOP2B抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoiningDNA拓扑异构酶2-β/TOP2B抗体 of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, beta, is localized to chromosome 3 and the alpha form is localized to chromosome 17. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have beenDNA拓扑异构酶2-β/TOP2B抗体 associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. Alternative splicing of this gene results in two transcript variants; however, the second variant has not yet been fully described. [provided by RefSeq, Jul 2008]
DNA拓扑异构酶2-β/TOP2B抗体Also known as:
Antigen MLAA 44; beta isozyme; DNA topoisomerase 2 beta; DNA topoisomerase 2-beta; DNA topoisomerase II 180 kD; DNA topoisomerase II; DNA topoisomerase II beta; DNA topoisomerase II beta isozyme; Top 2; TOP 2B; TOP IIB; Top2 beta; TOP2B; TOP2B_HUMAN; Top2beta; TOPIIB; Topo II beta; Topoisomerase (DNA) II beta 180kDa; Topoisomerase (DNA) II beta; Topoisomerase IIb; U937 associated antigen.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Chimpanzee, .
●
Immunogen: KLH conjugated synthetic peptide derived from human Topoisomerase II beta.
●
Predicted Molecular Weight: 183kDa.
DNA拓扑异构酶2-β/TOP2B抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
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kl063Po01白介素17(IL17)多克隆抗体Polyclonal Antibody to Interleukin 17 (IL17)
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kl064Cp01白介素18(IL18)多克隆抗体Polyclonal Antibody to Interleukin 18 (IL18)
kl064Eq01白介素18(IL18)多克隆抗体Polyclonal Antibody to Interleukin 18 (IL18)
kl064Ga01白介素18(IL18)多克隆抗体Polyclonal Antibody to Interleukin 18 (IL18)
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kl065Mu01白介素1受体Ⅱ(IL1R2)多克隆抗体Polyclonal Antibody to Interleukin 1 Receptor Type II (IL1R2)
kl065Ra01白介素1受体Ⅱ(IL1R2)多克隆抗体Polyclonal Antibody to Interleukin 1 Receptor Type II (IL1R2)
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企业名称
上海康朗生物科技有限公司
企业信息已认证
企业类型
信用代码
310112001510759
成立日期
2015-05-29
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100
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