Quantity size:
0.1ml
Concentration:
1mg/ml 磷酸化肌动蛋白相关蛋白2抗体 Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Actin polymerization is required for a variety of cell functions, including chemotaxis, cell migration, cell adhesion, and platelet activation. Cells trigger actin polymerization through either the de novo nucleation of filaments from monomeric actin, the severing of existing filaments to create uncapped barbed ends, or the uncapping of existing barbed ends. The nucleation of actin is a rate-limiting and unfavorable reaction in磷酸化肌动蛋白相关蛋白2抗体 actin polymerization and therefore requires the involvement of the Arp2/3 complex, which helps create new filaments and promotes the end-to-side cross-linking of actin filaments into the branching meshwork. The Arp2/3 complex consists of the actin-related proteins Arp2 and Arp3, and various other accessory proteins. The Arp2/3 complex promotes actin nucleation by binding the pointed end of actin filaments, or by associating with the side磷酸化肌动蛋白相关蛋白2抗体 of an existing filament, and nucleates growth in the barbed direction. In addition, the Arp2/3 complex also mediates actin cytoskeletal outgrowths that are regulated by the Rho family of small GTPases. In response to GTP-binding Cdc42, the Arp2/3 complex binds the Cdc42 substrates, namely the WASP proteins, and initiates the formation of lamellipodia and filopodia.
磷酸化肌动蛋白相关蛋白2抗体Also known as:
Arp2 (phospho T237 + T238);p-Arp2 (phospho T237 + T238); Actin like protein 2; Actin related protein 2; Actin-like protein 2; ACTIN-RELATED PROTEIN 2; ACTR2; ARP2 actin related protein 2 homolog (yeast); ARP2; ARP2/3 COMPLEX; ARP2_HUMAN; OTTHUMP00000159937; OTTHUMP00000202270.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Cow, Sheep, Fish, .
●
Immunogen: KLH conjugated synthesised phosphopeptide derived from human ARP2 around the phosphorylation site of Thr237.
●
Predicted Molecular Weight: 45kDa.
磷酸化肌动蛋白相关蛋白2抗体Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
kl482Po01内皮素1(EDN1)多克隆抗体Polyclonal Antibody to Endothelin 1 (EDN1)
kl028Si01红细胞生成素(EPO)多克隆抗体Polyclonal Antibody to Erythropoietin (EPO)
kl028Ca01红细胞生成素(EPO)多克隆抗体Polyclonal Antibody to Erythropoietin (EPO)
kl028Po01红细胞生成素(EPO)多克隆抗体Polyclonal Antibody to Erythropoietin (EPO)
kl028Cp01红细胞生成素(EPO)多克隆抗体Polyclonal Antibody to Erythropoietin (EPO)
kl028Eq01红细胞生成素(EPO)多克隆抗体Polyclonal Antibody to Erythropoietin (EPO)
kl116Hu01红细胞过氧化氢酶(EC)多克隆抗体Polyclonal Antibody to Erythrocyte Catalase (EC)
kl116Po01红细胞过氧化氢酶(EC)多克隆抗体Polyclonal Antibody to Erythrocyte Catalase (EC)
kl003Ge01雌酮(E1)多克隆抗体Polyclonal Antibody to Estrone (E1)
kl037Gu01纤连蛋白(FN)多克隆抗体Polyclonal Antibody to Fibronectin (FN)
kl037Ca01纤连蛋白(FN)多克隆抗体Polyclonal Antibody to Fibronectin (FN)
kl037Po01纤连蛋白(FN)多克隆抗体Polyclonal Antibody to Fibronectin (FN)
kl037Bo01纤连蛋白(FN)多克隆抗体Polyclonal Antibody to Fibronectin (FN)
kl037Cp01纤连蛋白(FN)多克隆抗体Polyclonal Antibody to Fibronectin (FN)
kl037Eq01纤连蛋白(FN)多克隆抗体Polyclonal Antibody to Fibronectin (FN)
kl610Ge01叶酸(FA)多克隆抗体Polyclonal Antibody to Folic Acid (FA)
kl759Ge01赤霉素(GA)多克隆抗体Polyclonal Antibody to Gibberellic Acid (GA)
kl084Hu01甘丙肽(GAL)多克隆抗体Polyclonal Antibody to Galanin (GAL)
kl084Mu01甘丙肽(GAL)多克隆抗体Polyclonal Antibody to Galanin (GAL)
kl084Ra01甘丙肽(GAL)多克隆抗体Polyclonal Antibody to Galanin (GAL)
kl900Ge01γ-氨基丁酸(γABA)多克隆抗体Polyclonal Antibody to Gamma-Aminobutyric Acid (gABA)
kl506Hu01胃泌素释放肽(GRP)多克隆抗体Polyclonal Antibody to Gastrin Releasing Peptide (GRP)
kl506Mu01胃泌素释放肽(GRP)多克隆抗体Polyclonal Antibody to Gastrin Releasing Peptide (GRP)
kl506Ra01胃泌素释放肽(GRP)多克隆抗体Polyclonal Antibody to Gastrin Releasing Peptide (GRP)
kl882Hu01胃泌素抑制肽(GIP)多克隆抗体Polyclonal Antibody to Gastric Inhibitory Polypeptide (GIP)
kl882Mu01胃泌素抑制肽(GIP)多克隆抗体Polyclonal Antibody to Gastric Inhibitory Polypeptide (GIP)
kl882Ra01胃泌素抑制肽(GIP)多克隆抗体Polyclonal Antibody to Gastric Inhibitory Polypeptide (GIP)
kl224Hu01胃泌素(GT)多克隆抗体Polyclonal Antibody to Gastrin (GT)
kl224Mu01胃泌素(GT)多克隆抗体Polyclonal Antibody to Gastrin (GT)
更多
企业名称
上海康朗生物科技有限公司
企业信息已认证
企业类型
信用代码
310112001510759
成立日期
2015-05-29
注册资本
100
经营范围
从事生物科技技术领域内技术开发、技术咨询、技术服务、技术转让,实验分析仪器、化工产品及原料(除危险化学品、监控化学品、烟花爆竹、民用爆竹物品、易制毒化学品)、仪器仪表、环保设备、酒店用品、皮革制品、床上用品、电子产品的销售。【依法须经批准的项目,经相关部门批准后方可开展经营活动】
上海康朗生物科技有限公司
公司地址
上海市闵行区闵北路88弄1-30号第22栋BV145室
客服电话